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BioLiP
Download all results in tab-seperated text for 20 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3uo9:A (2.3) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22049910 PDBbind: -logKd/Ki=7.10, IC50=0.08uM
    BindingDB: IC50=100nM, Kd=200nM
    2 3uo9:B (2.3) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22049910 MOAD: ic50=0.08uM
    PDBbind: -logKd/Ki=7.10, IC50=0.08uM
    BindingDB: IC50=100nM, Kd=200nM
    3 3uo9:C (2.3) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22049910 MOAD: ic50=0.08uM
    BindingDB: IC50=100nM, Kd=200nM
    4 3uo9:D (2.3) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22049910 PDBbind: -logKd/Ki=7.10, IC50=0.08uM
    BindingDB: IC50=100nM, Kd=200nM
    5 3voz:A (2.4) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22538822 MOAD: ic50=0.14uM
    PDBbind: -logKd/Ki=6.85, IC50=0.14uM
    BindingDB: IC50=100nM, Kd=200nM
    6 3vp1:A (2.3) BS01 04A 3.5.1.2 GO:0004359 ... O94925 22538822 PDBbind: -logKd/Ki=5.48, IC50=3.3uM
    BindingDB: IC50=100nM, Kd=200nM
    7 4jkt:A (2.77) BS01 04A 3.5.1.2 GO:0004359 ... D3Z7P3 23935106 PDBbind: -logKd/Ki=7.09, IC50=80.4nM
    8 4jkt:B (2.77) BS01 04A 3.5.1.2 GO:0004359 ... D3Z7P3 23935106 PDBbind: -logKd/Ki=7.09, IC50=80.4nM
    9 4jkt:C (2.77) BS01 04A 3.5.1.2 GO:0004359 ... D3Z7P3 23935106 PDBbind: -logKd/Ki=7.09, IC50=80.4nM
    10 4jkt:D (2.77) BS01 04A 3.5.1.2 GO:0004359 ... D3Z7P3 23935106 PDBbind: -logKd/Ki=7.09, IC50=80.4nM
    11 5uqe:A (3.6) BS01 04A 3.5.1.2 GO:0004359 ... O94925 28526749 BindingDB: IC50=100nM, Kd=200nM
    12 5uqe:B (3.6) BS01 04A 3.5.1.2 GO:0004359 ... O94925 28526749 BindingDB: IC50=100nM, Kd=200nM
    13 5uqe:C (3.6) BS01 04A 3.5.1.2 GO:0004359 ... O94925 28526749 BindingDB: IC50=100nM, Kd=200nM
    14 5uqe:D (3.6) BS01 04A 3.5.1.2 GO:0004359 ... O94925 28526749 BindingDB: IC50=100nM, Kd=200nM
    15 5uqe:F (3.6) BS01 04A 3.5.1.2 GO:0004359 ... O94925 28526749 BindingDB: IC50=100nM, Kd=200nM
    16 7rgg:A (3.0) BS01 04A 3.5.1.2 GO:0004359 ... O94925 34954143
    17 7rgg:B (3.0) BS01 04A 3.5.1.2 GO:0004359 ... O94925 34954143
    18 7rgg:C (3.0) BS01 04A 3.5.1.2 GO:0004359 ... O94925 34954143
    19 7rgg:D (3.0) BS01 04A 3.5.1.2 GO:0004359 ... O94925 34954143
    20 8bsk:A (2.1) BS01 04A 3.5.1.2 GO:0004359 ... O94925 31199640
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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