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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 101m:A (2.07) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    2 102m:A (1.84) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    3 103m:A (2.07) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    4 104m:A (1.71) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    5 105m:A (2.02) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    6 106m:A (1.99) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    7 107m:A (2.09) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    8 108m:A (2.67) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    9 109m:A (1.83) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    10 10gs:A (2.2) BS01 VWW 2.5.1.18 GO:0000302 ... P09211 9398518 MOAD: Ki=0.4uM
    PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    BindingDB: Ki=420nM
    11 10gs:B (2.2) BS01 VWW 2.5.1.18 GO:0000302 ... P09211 9398518 MOAD: Ki=0.4uM
    PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    BindingDB: Ki=420nM
    12 110m:A (1.77) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    13 110m:A (1.77) BS02 MNC 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    14 111m:A (1.88) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    15 112m:A (2.34) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    16 112m:A (2.34) BS02 NPN 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 N/A
    17 117e:A (2.15) BS01 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    18 117e:A (2.15) BS02 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    19 117e:A (2.15) BS03 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    20 117e:A (2.15) BS04 PO4 3.6.1.1 GO:0000287 ... P00817 9878371
    21 117e:A (2.15) BS05 PO4 3.6.1.1 GO:0000287 ... P00817 9878371
    22 117e:B (2.15) BS01 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    23 117e:B (2.15) BS02 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    24 117e:B (2.15) BS03 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    25 117e:B (2.15) BS04 MN 3.6.1.1 GO:0000287 ... P00817 9878371
    26 117e:B (2.15) BS05 PO4 3.6.1.1 GO:0000287 ... P00817 9878371
    27 11as:A (2.5) BS01 ASN 6.3.1.1 GO:0004071 ... P00963 9437423
    28 11as:B (2.5) BS01 ASN 6.3.1.1 GO:0004071 ... P00963 9437423
    29 11ba:A (2.06) BS01 UPA 4.6.1.18 GO:0003676 ... P00669 10082366
    30 11ba:B (2.06) BS01 UPA 4.6.1.18 GO:0003676 ... P00669 10082366
    31 11bg:A (1.9) BS01 U2G 4.6.1.18 GO:0003676 ... P00669 10543951
    32 11bg:A (1.9) BS02 U2G 4.6.1.18 GO:0003676 ... P00669 10543951
    33 11bg:A (1.9) BS03 U2G 4.6.1.18 GO:0003676 ... P00669 10543951
    34 11bg:B (1.9) BS01 U2G 4.6.1.18 GO:0003676 ... P00669 10543951
    35 11bg:B (1.9) BS02 U2G 4.6.1.18 GO:0003676 ... P00669 10543951
    36 11gs:A (2.3) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    37 11gs:A (2.3) BS02 EAA 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    BindingDB: IC50=2.6e+4nM
    38 11gs:B (2.3) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    39 11gs:B (2.3) BS02 EAA 2.5.1.18 GO:0000302 ... P09211 9426214 PDBbind: -logKd/Ki=5.82, Ki=1.5uM
    BindingDB: IC50=2.6e+4nM
    40 121p:A (1.54) BS01 MG 3.6.5.2 GO:0003924 ... P01112 N/A
    41 12as:A (2.2) BS01 ASN 6.3.1.1 GO:0004071 ... P00963 9437423
    42 12as:A (2.2) BS02 AMP 6.3.1.1 GO:0004071 ... P00963 9437423
    43 12as:B (2.2) BS01 ASN 6.3.1.1 GO:0004071 ... P00963 9437423
    44 12as:B (2.2) BS02 AMP 6.3.1.1 GO:0004071 ... P00963 9437423
    45 12ca:A (2.4) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 1910042
    46 12gs:A (2.1) BS01 0HH 2.5.1.18 GO:0000302 ... P09211 10452896
    47 12gs:B (2.1) BS01 0HH 2.5.1.18 GO:0000302 ... P09211 10452896
    48 13gs:A (1.9) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 10452896
    49 13gs:A (1.9) BS02 SAS 2.5.1.18 GO:0000302 ... P09211 10452896 MOAD: Ki=24uM
    PDBbind: -logKd/Ki=4.62, Ki=24uM
    50 13gs:B (1.9) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 10452896
    51 13gs:B (1.9) BS02 SAS 2.5.1.18 GO:0000302 ... P09211 10452896 MOAD: Ki=24uM
    52 13pk:A (2.5) BS01 ADP 2.7.2.3 GO:0004618 ... P07378 9000079
    53 13pk:B (2.5) BS01 ADP 2.7.2.3 GO:0004618 ... P07378 9000079
    54 13pk:C (2.5) BS01 ADP 2.7.2.3 GO:0004618 ... P07378 9000079
    55 13pk:D (2.5) BS01 ADP 2.7.2.3 GO:0004618 ... P07378 9000079
    56 148l:E (1.9) BS01 peptide 3.2.1.17 GO:0003796 ... P00720 8266098
    57 148l:E (1.9) BS02 MUB 3.2.1.17 GO:0003796 ... P00720 8266098
    58 16pk:A (1.6) BS01 BIS 2.7.2.3 GO:0004618 ... P07378 9642090 PDBbind: -logKd/Ki=5.22, Ki=6uM
    59 17gs:A (1.9) BS01 GTX 2.5.1.18 GO:0000302 ... P09211 N/A
    60 17gs:B (1.9) BS01 GTX 2.5.1.18 GO:0000302 ... P09211 N/A
    61 182l:A (1.8) BS01 BZF 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Ka=8900M^-1
    62 183l:A (1.8) BS01 DEN 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Ka=5170M^-1
    63 184l:A (1.8) BS01 I4B 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Ka=51000M^-1
    PDBbind: -logKd/Ki=4.72, Kd=19uM
    64 185l:A (1.8) BS01 IND 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Kd=289uM
    PDBbind: -logKd/Ki=3.54, Kd=290uM
    65 186l:A (1.8) BS01 N4B 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Kd=14uM
    PDBbind: -logKd/Ki=4.85, Kd=14uM
    66 187l:A (1.8) BS01 PXY 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Kd=422uM
    PDBbind: -logKd/Ki=3.37, Kd=422uM
    BindingDB: Kd=151000nM
    67 188l:A (1.8) BS01 OXE 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Kd=469uM
    PDBbind: -logKd/Ki=3.33, Kd=470uM
    68 18gs:A (1.9) BS01 GDN 2.5.1.18 GO:0000302 ... P09211 10452896
    69 18gs:B (1.9) BS01 GDN 2.5.1.18 GO:0000302 ... P09211 10452896
    70 193l:A (1.33) BS01 NA 3.2.1.17 GO:0003796 ... P00698 15299672
    71 194l:A (1.4) BS01 NA 3.2.1.17 GO:0003796 ... P00698 15299672
    72 19gs:A (1.9) BS01 BSP 2.5.1.18 GO:0000302 ... P09211 10452896
    73 19gs:A (1.9) BS02 GSH 2.5.1.18 GO:0000302 ... P09211 10452896
    74 19gs:B (1.9) BS01 BSP 2.5.1.18 GO:0000302 ... P09211 10452896
    75 19gs:B (1.9) BS02 GSH 2.5.1.18 GO:0000302 ... P09211 10452896
    76 19hc:A (1.8) BS01 HEM ? GO:0009055 ... Q9RN68 10368280
    77 19hc:A (1.8) BS02 HEM ? GO:0009055 ... Q9RN68 10368280
    78 19hc:A (1.8) BS03 HEM ? GO:0009055 ... Q9RN68 10368280
    79 19hc:A (1.8) BS04 HEM ? GO:0009055 ... Q9RN68 10368280
    80 19hc:A (1.8) BS05 HEM ? GO:0009055 ... Q9RN68 10368280
    81 19hc:A (1.8) BS06 HEM ? GO:0009055 ... Q9RN68 10368280
    82 19hc:A (1.8) BS07 HEM ? GO:0009055 ... Q9RN68 10368280
    83 19hc:A (1.8) BS08 HEM ? GO:0009055 ... Q9RN68 10368280
    84 19hc:A (1.8) BS09 HEM ? GO:0009055 ... Q9RN68 10368280
    85 19hc:A (1.8) BS10 HEM ? GO:0009055 ... Q9RN68 10368280
    86 19hc:B (1.8) BS01 HEM ? GO:0009055 ... Q9RN68 10368280
    87 19hc:B (1.8) BS02 HEM ? GO:0009055 ... Q9RN68 10368280
    88 19hc:B (1.8) BS03 HEM ? GO:0009055 ... Q9RN68 10368280
    89 19hc:B (1.8) BS04 HEM ? GO:0009055 ... Q9RN68 10368280
    90 19hc:B (1.8) BS05 HEM ? GO:0009055 ... Q9RN68 10368280
    91 19hc:B (1.8) BS06 HEM ? GO:0009055 ... Q9RN68 10368280
    92 19hc:B (1.8) BS07 HEM ? GO:0009055 ... Q9RN68 10368280
    93 19hc:B (1.8) BS08 HEM ? GO:0009055 ... Q9RN68 10368280
    94 19hc:B (1.8) BS09 HEM ? GO:0009055 ... Q9RN68 10368280
    95 1a00:A (2.0) BS01 HEM ? GO:0004601 ... P69905 9521756
    96 1a00:B (2.0) BS01 HEM ? GO:0004601 ... P68871 9521756
    97 1a00:C (2.0) BS01 HEM ? GO:0004601 ... P69905 9521756
    98 1a00:D (2.0) BS01 HEM ? GO:0004601 ... P68871 9521756
    99 1a01:A (1.8) BS01 HEM ? GO:0004601 ... P69905 9521756
    100 1a01:B (1.8) BS01 HEM ? GO:0004601 ... P68871 9521756
    101 1a01:C (1.8) BS01 HEM ? GO:0004601 ... P69905 9521756
    102 1a01:D (1.8) BS01 HEM ? GO:0004601 ... P68871 9521756
    103 1a05:A (2.0) BS01 IPM 1.1.1.85 GO:0000287 ... Q56268 9739088
    104 1a05:B (2.0) BS01 IPM 1.1.1.85 GO:0000287 ... Q56268 9739088
    105 1a0c:A (2.5) BS01 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    106 1a0c:A (2.5) BS02 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    107 1a0c:B (2.5) BS01 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    108 1a0c:B (2.5) BS02 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    109 1a0c:C (2.5) BS01 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    110 1a0c:C (2.5) BS02 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    111 1a0c:D (2.5) BS01 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    112 1a0c:D (2.5) BS02 CO 5.3.1.5 GO:0000287 ... P19148 N/A
    113 1a0d:A (3.0) BS01 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    114 1a0d:A (3.0) BS02 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    115 1a0d:B (3.0) BS01 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    116 1a0d:B (3.0) BS02 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    117 1a0d:C (3.0) BS01 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    118 1a0d:C (3.0) BS02 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    119 1a0d:D (3.0) BS01 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    120 1a0d:D (3.0) BS02 MN 5.3.1.5 GO:0000287 ... P54273 N/A
    121 1a0e:A (2.7) BS01 CO 5.3.1.5 GO:0000287 ... P45687 N/A
    122 1a0e:A (2.7) BS02 CO 5.3.1.5 GO:0000287 ... P45687 N/A
    123 1a0e:D (2.7) BS01 CO 5.3.1.5 GO:0000287 ... P45687 N/A
    124 1a0e:D (2.7) BS02 CO 5.3.1.5 GO:0000287 ... P45687 N/A
    125 1a0f:A (2.1) BS01 GTS 2.5.1.18 GO:0004364 ... P0A9D2 9680481
    126 1a0f:B (2.1) BS01 GTS 2.5.1.18 GO:0004364 ... P0A9D2 9680481
    127 1a0j:A (1.7) BS01 CA 3.4.21.4 GO:0004252 ... P35033 9757092
    128 1a0l:A (3.0) BS01 APA 3.4.21.59 GO:0004252 ... P20231 9521329
    129 1a0l:B (3.0) BS01 APA 3.4.21.59 GO:0004252 ... P20231 9521329
    130 1a0l:C (3.0) BS01 APA 3.4.21.59 GO:0004252 ... P20231 9521329
    131 1a0l:D (3.0) BS01 APA 3.4.21.59 GO:0004252 ... P20231 9521329
    132 1a0o:A (2.95) BS01 MN ? GO:0000156 ... P0AE67 9437425
    133 1a0o:C (2.95) BS01 MN ? GO:0000156 ... P0AE67 9437425
    134 1a0o:E (2.95) BS01 MN ? GO:0000156 ... P0AE67 9437425
    135 1a0o:G (2.95) BS01 MN ? GO:0000156 ... P0AE67 9437425
    136 1a0q:L (2.3) BS01 ZN ? GO:0005576 ... P01837 9753552
    137 1a0q:L (2.3) BS02 HEP ? GO:0005576 ... P01837 9753552 PDBbind: -logKd/Ki=7.57, Ki=27nM
    138 1a0r:B (2.8) BS01 FAR ? GO:0005515 ... P62871 9739091
    139 1a0s:P (2.4) BS01 CA ? GO:0015288 ... P22340 9437428
    140 1a0s:Q (2.4) BS01 CA ? GO:0015288 ... P22340 9437428
    141 1a0s:R (2.4) BS01 CA ? GO:0015288 ... P22340 9437428
    142 1a0t:P (2.4) BS01 GLC ? GO:0015288 ... P22340 9437428
    143 1a0t:P (2.4) BS02 FRU ? GO:0015288 ... P22340 9437428
    144 1a0t:P (2.4) BS03 GLC ? GO:0015288 ... P22340 9437428
    145 1a0t:P (2.4) BS04 CA ? GO:0015288 ... P22340 9437428
    146 1a0t:Q (2.4) BS01 GLC ? GO:0015288 ... P22340 9437428
    147 1a0t:Q (2.4) BS02 FRU ? GO:0015288 ... P22340 9437428
    148 1a0t:Q (2.4) BS03 GLC ? GO:0015288 ... P22340 9437428
    149 1a0t:Q (2.4) BS04 CA ? GO:0015288 ... P22340 9437428
    150 1a0t:R (2.4) BS01 GLC ? GO:0015288 ... P22340 9437428
    151 1a0t:R (2.4) BS02 FRU ? GO:0015288 ... P22340 9437428
    152 1a0t:R (2.4) BS03 GLC ? GO:0015288 ... P22340 9437428
    153 1a0t:R (2.4) BS04 CA ? GO:0015288 ... P22340 9437428
    154 1a0u:A (2.14) BS01 HEM ? GO:0004601 ... P69905 9521756
    155 1a0u:B (2.14) BS01 HEM ? GO:0004601 ... P68871 9521756
    156 1a0u:C (2.14) BS01 HEM ? GO:0004601 ... P69905 9521756
    157 1a0u:D (2.14) BS01 HEM ? GO:0004601 ... P68871 9521756
    158 1a0z:A (2.0) BS01 HEM ? GO:0004601 ... P69905 9521756
    159 1a0z:B (2.0) BS01 HEM ? GO:0004601 ... P68871 9521756
    160 1a0z:C (2.0) BS01 HEM ? GO:0004601 ... P69905 9521756
    161 1a0z:D (2.0) BS01 HEM ? GO:0004601 ... P68871 9521756
    162 1a14:N (2.5) BS01 CA 3.2.1.18 GO:0004308 ... P03472 9642070
    163 1a16:A (2.3) BS01 PRO 3.4.11.9 GO:0004177 ... P15034 9520390
    164 1a16:A (2.3) BS02 LEU 3.4.11.9 GO:0004177 ... P15034 9520390
    165 1a16:A (2.3) BS03 MN 3.4.11.9 GO:0004177 ... P15034 9520390
    166 1a16:A (2.3) BS04 MN 3.4.11.9 GO:0004177 ... P15034 9520390
    167 1a27:A (1.9) BS01 EST 1.1.1.51
    1.1.1.62
    GO:0004303 ... P14061 N/A
    168 1a27:A (1.9) BS02 NAP 1.1.1.51
    1.1.1.62
    GO:0004303 ... P14061 N/A
    169 1a29:A (2.74) BS01 CA ? GO:0000922 ... P62157 9799490
    170 1a29:A (2.74) BS02 CA ? GO:0000922 ... P62157 9799490
    171 1a29:A (2.74) BS03 CA ? GO:0000922 ... P62157 9799490
    172 1a29:A (2.74) BS04 CA ? GO:0000922 ... P62157 9799490
    173 1a29:A (2.74) BS05 TFP ? GO:0000922 ... P62157 9799490 BindingDB: Kd=5000nM
    174 1a29:A (2.74) BS06 TFP ? GO:0000922 ... P62157 9799490 BindingDB: Kd=5000nM
    175 1a2b:A (2.4) BS01 MG 3.6.5.2 GO:0000902 ... P61586 9545299
    176 1a2b:A (2.4) BS02 GSP 3.6.5.2 GO:0000902 ... P61586 9545299
    177 1a2i:A (-1.00) BS01 HEC ? GO:0009055 ... P00131 9710542
    178 1a2i:A (-1.00) BS02 HEC ? GO:0009055 ... P00131 9710542
    179 1a2i:A (-1.00) BS03 HEC ? GO:0009055 ... P00131 9710542
    180 1a2i:A (-1.00) BS04 HEC ? GO:0009055 ... P00131 9710542
    181 1a2n:A (2.8) BS01 TET 2.5.1.7 GO:0003824 ... P0A749 9485407
    182 1a2s:A (-1.00) BS01 HEC ? GO:0005506 ... Q09099 9538000
    183 1a2v:A (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    184 1a2v:B (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    185 1a2v:C (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    186 1a2v:D (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    187 1a2v:E (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    188 1a2v:F (2.4) BS01 CU 1.4.3.21 GO:0005507 ... P12807 15299901
    189 1a2x:A (2.3) BS01 CA ? GO:0005509 ... P02586 9560191
    190 1a2x:A (2.3) BS02 CA ? GO:0005509 ... P02586 9560191
    191 1a31:A (2.1) BS01 dna 5.6.2.1 GO:0003677 ... P11387 9488644
    192 1a31:A (2.1) BS02 dna 5.6.2.1 GO:0003677 ... P11387 9488644
    193 1a34:A (1.81) BS01 rna ? GO:0005198 ... P17574 9514737
    194 1a34:A (1.81) BS02 rna ? GO:0005198 ... P17574 9514737
    195 1a34:A (1.81) BS03 SO4 ? GO:0005198 ... P17574 9514737
    196 1a34:A (1.81) BS04 U ? GO:0005198 ... P17574 9514737
    197 1a35:A (2.5) BS01 dna 5.6.2.1 GO:0003677 ... P11387 9488644
    198 1a35:A (2.5) BS02 dna 5.6.2.1 GO:0003677 ... P11387 9488644
    199 1a36:A (2.8) BS01 dna 5.6.2.1 GO:0003677 ... P11387 9488652
    200 1a36:A (2.8) BS02 dna 5.6.2.1 GO:0003677 ... P11387 9488652

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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