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BioLiP
Download all results in tab-seperated text for 2 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    Peptide
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 4zvp:A
    (2.5)
    BS01 >4zvp:E (identical to 6bdv:C, 6bfj:C, 6bfk:F, 6bfk:E, 6bfl:C, 6bfo:D, 6bg0:G, 6bg0:F, 6bg1:B, 6bg4:C, 6bg4:D, 6bgk:F, 6bgk:H, 6bgq:K, 6bgq:L, 6bgr:C, 6bgs:B, 6bh9:D, 6bh9:G, 6bha:C, 2cjx:I, 4dcj:C, 4dcj:F, 4dco:C, 4dco:F, 4dcp:C, 4dcp:F, 8dgz:C, 8dgz:D, 2dko:I, 4eha:F, 4eha:B, 4ehd:B, 4ehf:B, 4ehh:B, 4ehk:B, 4ehk:D, 4ehl:B, 4ehl:D, 4ehn:B, 1f1j:C, 1f1j:D, 3h1p:C, 3h1p:D, 2h5i:C, 4hqr:E, 4hqr:F, 5i9b:B, 5i9t:D, 5i9t:E, 5iab:D, 5iab:E, 5iae:D, 5iae:E, 5iag:B, 5iaj:B, 5iak:B, 5ian:B, 5iar:B, 5ias:B, 5ibc:B, 5ibp:B, 5ibr:B, 5ibr:D, 3itn:B, 2j30:B, 2j31:B, 2j32:B, 2j33:B, 5jft:F, 5jft:C, 7jl7:F, 4jr0:C, 4jr0:D, 4jr1:C, 4jr1:D, 4jr2:C, 4jr2:D, 1m72:D, 1m72:E, 1m72:F, 1pau:C, 3pcx:B, 3pd0:B, 3pd1:B, 6pdq:F, 6pdq:G, 4qtx:E, 4qty:F, 4qu0:E, 4qu5:B, 4qu8:F, 4qu9:E, 4qua:D, 4qub:D, 4qud:D, 4qud:C, 4que:H, 4que:J, 4qug:D, 4qug:B, 4quh:I, 4quh:J, 4qui:D, 4qui:C, 4quj:F, 4qul:G, 4qul:F, 1rhk:C, 6wi4:D, 6wi4:E, 7wq8:B, 6x8i:E, 6x8i:F, 6x8j:E, 6x8j:F, 4zvp:F, 4zvr:E, 4zvr:F, 4zvs:E, 4zvs:F)
    DEVD
    3.4.22.60 GO:0004197 ... P55210 27032039
    2 4zvp:B
    (2.5)
    BS01 >4zvp:E (identical to 6bdv:C, 6bfj:C, 6bfk:F, 6bfk:E, 6bfl:C, 6bfo:D, 6bg0:G, 6bg0:F, 6bg1:B, 6bg4:C, 6bg4:D, 6bgk:F, 6bgk:H, 6bgq:K, 6bgq:L, 6bgr:C, 6bgs:B, 6bh9:D, 6bh9:G, 6bha:C, 2cjx:I, 4dcj:C, 4dcj:F, 4dco:C, 4dco:F, 4dcp:C, 4dcp:F, 8dgz:C, 8dgz:D, 2dko:I, 4eha:F, 4eha:B, 4ehd:B, 4ehf:B, 4ehh:B, 4ehk:B, 4ehk:D, 4ehl:B, 4ehl:D, 4ehn:B, 1f1j:C, 1f1j:D, 3h1p:C, 3h1p:D, 2h5i:C, 4hqr:E, 4hqr:F, 5i9b:B, 5i9t:D, 5i9t:E, 5iab:D, 5iab:E, 5iae:D, 5iae:E, 5iag:B, 5iaj:B, 5iak:B, 5ian:B, 5iar:B, 5ias:B, 5ibc:B, 5ibp:B, 5ibr:B, 5ibr:D, 3itn:B, 2j30:B, 2j31:B, 2j32:B, 2j33:B, 5jft:F, 5jft:C, 7jl7:F, 4jr0:C, 4jr0:D, 4jr1:C, 4jr1:D, 4jr2:C, 4jr2:D, 1m72:D, 1m72:E, 1m72:F, 1pau:C, 3pcx:B, 3pd0:B, 3pd1:B, 6pdq:F, 6pdq:G, 4qtx:E, 4qty:F, 4qu0:E, 4qu5:B, 4qu8:F, 4qu9:E, 4qua:D, 4qub:D, 4qud:D, 4qud:C, 4que:H, 4que:J, 4qug:D, 4qug:B, 4quh:I, 4quh:J, 4qui:D, 4qui:C, 4quj:F, 4qul:G, 4qul:F, 1rhk:C, 6wi4:D, 6wi4:E, 7wq8:B, 6x8i:E, 6x8i:F, 6x8j:E, 6x8j:F, 4zvp:F, 4zvr:E, 4zvr:F, 4zvs:E, 4zvs:F)
    DEVD
    3.4.22.60 GO:0004197 ... P55210 27032039

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218