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●I-TASSER ●D-I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●D-QUARK ●DRfold ●DRfold2 ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred ●TCRfinder

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●DeepMSA2 ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP Library
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    8401 4ehz:C (2.174) BS01 JAK 2.7.10.2 GO:0004672 ... P23458 22698084 MOAD: Ki=10nM
    BindingDB: EC50=250nM, Ki=10.0nM
    8402 4ehz:D (2.174) BS01 JAK 2.7.10.2 GO:0004672 ... P23458 22698084 MOAD: Ki=10nM
    BindingDB: EC50=250nM, Ki=10.0nM
    8403 4ej2:A (2.65) BS01 D1F 2.4.1.1 GO:0000166 ... P00489 22770609 PDBbind: -logKd/Ki=2.49, Ki=3204uM
    BindingDB: IC50=6100000nM
    8404 4ejg:A (2.5) BS02 NCT 1.14.14.1 GO:0004497 ... Q16696 22700965 BindingDB: Kd=54000nM, Ki=72000nM
    8405 4ejg:B (2.5) BS02 NCT 1.14.14.1 GO:0004497 ... Q16696 22700965 BindingDB: Kd=54000nM, Ki=72000nM
    8406 4ejg:C (2.5) BS02 NCT 1.14.14.1 GO:0004497 ... Q16696 22700965 BindingDB: Kd=54000nM, Ki=72000nM
    8407 4ejg:D (2.5) BS02 NCT 1.14.14.1 GO:0004497 ... Q16696 22700965 BindingDB: Kd=54000nM, Ki=72000nM
    8408 4ejj:A (2.3) BS02 NCT 1.14.14.- GO:0004497 ... P11509 22700965 MOAD: Kd=470uM
    BindingDB: Ki=130000nM, Kd=470000nM, IC50=2.63e+4nM
    8409 4ejj:B (2.3) BS02 NCT 1.14.14.- GO:0004497 ... P11509 22700965 MOAD: Kd=470uM
    BindingDB: Ki=130000nM, Kd=470000nM, IC50=2.63e+4nM
    8410 4ejj:C (2.3) BS02 NCT 1.14.14.- GO:0004497 ... P11509 22700965 MOAD: Kd=470uM
    BindingDB: Ki=130000nM, Kd=470000nM, IC50=2.63e+4nM
    8411 4ejn:A (2.19) BS01 0R4 2.7.11.1 GO:0001649 ... P31749 22533986 MOAD: ic50=0.005uM
    PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=44nM
    8412 4ek4:A (1.26) BS01 1CK 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: kon=3.57E+04M-1-s-1, koff=3.15E+00s-1, Kd=33200nM
    8413 4ek5:A (1.6) BS01 03K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: koff=6.10E-02s-1, kon=3.35E+05M-1-s-1, Kd=362nM
    8414 4ek6:A (1.52) BS01 10K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=910nM, IC50=3nM
    8415 4ek8:A (1.7) BS01 16K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=4380nM, kon=2.94E+05M-1-s-1, koff=1.69E-02s-1, Ki=110nM
    8416 4ek9:A (2.5) BS01 EP4 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 MOAD: Ki=38000nM
    PDBbind: -logKd/Ki=4.42, Ki=38000nM
    BindingDB: Ki=9000nM
    8417 4eke:A (2.6) BS01 D1I 2.4.1.1 GO:0000166 ... P00489 22770609 PDBbind: -logKd/Ki=4.48, Ki=33.4uM
    BindingDB: Ki=33400nM
    8418 4ekg:A (2.8) BS01 0QJ 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 PDBbind: -logKd/Ki=8.77, Kd=1.7nM
    BindingDB: Ki=13nM
    8419 4eki:A (2.85) BS01 0QK 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 PDBbind: -logKd/Ki=10.00, Kd=0.10nM
    BindingDB: Ki=0.300000nM, IC50=0.400000nM, EC50=9.0nM, Kd=0.250000nM
    8420 4ekl:A (2.0) BS01 0RF 2.7.11.1 GO:0004672 ... P31749 22569334 MOAD: ic50=5nM
    BindingDB: IC50=2.60nM
    8421 4ekq:A (1.54) BS01 NPO 3.2.1.17 GO:0003796 ... P00720 22988064 MOAD: Kd=2uM
    BindingDB: Kd=3000nM
    8422 4ekq:A (1.54) BS02 NPO 3.2.1.17 GO:0003796 ... P00720 22988064 MOAD: Kd=2uM
    BindingDB: Kd=3000nM
    8423 4ekq:B (1.54) BS01 NPO 3.2.1.17 GO:0003796 ... P00720 22988064 MOAD: Kd=2uM
    BindingDB: Kd=3000nM
    8424 4ekv:A (2.0) BS01 BTN ? GO:0005576 ... P22629 22536357 MOAD: Kd=0.000000064M
    BindingDB: Kd=1.000000nM
    8425 4eky:A (2.45) BS01 D1J 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=303uM
    PDBbind: -logKd/Ki=3.52, Ki=303.0uM
    BindingDB: Ki=303000nM
    8426 4el0:A (2.4) BS01 D1K 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=32.4uM
    PDBbind: -logKd/Ki=4.49, Ki=32.4uM
    BindingDB: Ki=32400nM
    8427 4el5:A (2.0) BS01 D1M 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=4.7uM
    PDBbind: -logKd/Ki=5.37, Ki=4.3uM
    BindingDB: Ki=4700nM
    8428 4ema:A (2.545) BS01 BRL ? GO:0003677 ... P37231 22649490 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    8429 4emt:A (1.5) BS01 C2E ? GO:0002218 ... Q86WV6 22728658 Manual survey: Kd=5uM (22728658)
    MOAD: Kd=4.63uM
    PDBbind: -logKd/Ki=5.30, Kd~5uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8430 4emt:B (1.5) BS01 C2E ? GO:0002218 ... Q86WV6 22728658 Manual survey: Kd=5uM (22728658)
    PDBbind: -logKd/Ki=5.30, Kd~5uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8431 4eoi:A (2.0) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    8432 4eoi:C (2.0) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=253nM, Ki=340nM
    8433 4eok:A (2.57) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=5.07, Ki=8600nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    8434 4eok:C (2.57) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    8435 4eol:A (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    8436 4eol:C (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=253nM, Ki=340nM
    8437 4eon:A (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    8438 4eon:C (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=253nM, Ki=340nM
    8439 4eop:A (1.99) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    8440 4eop:C (1.99) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=253nM, Ki=340nM
    8441 4eor:A (2.2) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 MOAD: Ki=500nM
    PDBbind: -logKd/Ki=6.30, Ki=500nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    8442 4eor:C (2.2) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 MOAD: Ki=500nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    8443 4eos:A (2.57) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    8444 4eos:C (2.57) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 BindingDB: IC50=253nM, Ki=340nM
    8445 4epw:A (1.7) BS02 0QV 3.6.5.2 GO:0003924 ... P01116 22566140 BindingDB: Kd=420000nM
    8446 4eqc:A (2.01) BS01 XR1 2.7.11.1 GO:0004672 ... Q13153 23960073 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=2.8nM
    8447 4er0:A (2.5) BS01 AW1 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: Kd=130nM, IC50=100nM, EC50=9.0nM, Ki=0.720000nM
    8448 4er3:A (2.4) BS01 0QK 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: Ki=0.300000nM, IC50=0.400000nM, EC50=9.0nM, Kd=0.250000nM
    8449 4er5:A (2.57) BS01 0QK 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: Ki=0.300000nM, IC50=0.400000nM, EC50=9.0nM, Kd=0.250000nM
    8450 4er5:A (2.57) BS02 0QK 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: Ki=0.300000nM, IC50=0.400000nM, EC50=9.0nM, Kd=0.250000nM
    8451 4er6:A (2.3) BS01 AW2 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: Kd=0.060000nM, IC50=8.8nM, EC50=9.0nM
    8452 4erf:A (2.0) BS01 0R3 2.3.2.27 GO:0005634 ... Q00987 22524527 MOAD: Kd=0.4nM
    PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=0.4nM, IC50=4.1nM
    8453 4erf:C (2.0) BS01 0R3 2.3.2.27 GO:0005634 ... Q00987 22524527 MOAD: Kd=0.4nM
    BindingDB: Kd=0.4nM, IC50=4.1nM
    8454 4erf:E (2.0) BS01 0R3 2.3.2.27 GO:0005634 ... Q00987 22524527 MOAD: Kd=0.4nM
    BindingDB: Kd=0.4nM, IC50=4.1nM
    8455 4erk:A (2.2) BS01 OLO 2.7.11.24 GO:0000165 ... P63086 9753691 MOAD: ic50=27uM
    PDBbind: -logKd/Ki=4.57, IC50=27uM
    BindingDB: IC50=27000nM
    8456 4eut:A (2.6) BS01 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8457 4eut:B (2.6) BS01 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8458 4euu:A (1.8) BS01 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8459 4euu:A (1.8) BS02 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8460 4euu:B (1.8) BS01 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8461 4euu:B (1.8) BS02 BX7 2.7.11.1 GO:0004672 ... Q9UHD2 22619329 BindingDB: IC50=8.0nM, Kd=158nM
    8462 4ewh:A (2.5) BS01 T77 2.7.10.2
    2.7.11.1    		 GO:0004672 ... Q07912 22929232 MOAD: Ki=0.0003uM
    PDBbind: -logKd/Ki=9.52, Ki=0.3nM
    BindingDB: Ki=0.3nM
    8463 4ewh:B (2.5) BS01 T77 2.7.10.2
    2.7.11.1    		 GO:0004672 ... Q07912 22929232 MOAD: Ki=0.0003uM
    BindingDB: Ki=0.3nM
    8464 4ewq:A (2.1) BS01 GG5 2.7.11.24 GO:0000077 ... Q16539 30978288 BindingDB: Ki=600nM, IC50=67nM
    8465 4ews:A (2.59) BS05 0RP ? GO:0005548 ... P11597 22961980 BindingDB: IC50=39nM
    8466 4exs:A (2.4) BS01 X8Z 3.5.2.6 N/A C7C422 22713171 MOAD: Ki=39uM
    BindingDB: Kd=14000nM, IC50=50119nM
    8467 4exs:B (2.4) BS01 X8Z 3.5.2.6 N/A C7C422 22713171 MOAD: Ki=39uM
    PDBbind: -logKd/Ki=4.41, Ki=39.0uM
    BindingDB: Kd=14000nM, IC50=50119nM
    8468 4ey5:A (2.3012) BS01 HUP 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=260nM
    8469 4ey5:B (2.3012) BS01 HUP 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=260nM
    8470 4ey6:A (2.3983) BS01 GNT 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=800nM, Ki=62nM, EC50=1100nM
    8471 4ey6:B (2.3983) BS01 GNT 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=800nM, Ki=62nM, EC50=1100nM
    8472 4ey7:A (2.3509) BS01 E20 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=10.0nM, Ki=20.5nM, EC50=43nM
    8473 4ey7:B (2.3509) BS01 E20 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=10.0nM, Ki=20.5nM, EC50=43nM
    8474 4eyj:A (2.102) BS01 N61 2.7.11.24 GO:0000165 ... O15264 23187130 PDBbind: -logKd/Ki=6.21, IC50=620nM
    BindingDB: IC50=619.5nM
    8475 4eym:A (2.353) BS01 0RX 2.7.11.24 GO:0000165 ... O15264 23187130 PDBbind: -logKd/Ki=4.01, IC50=98747nM
    BindingDB: IC50=14884nM
    8476 4ez5:A (2.7) BS01 0RS 2.7.11.22 GO:0000082 ... Q00534 24900493 PDBbind: -logKd/Ki=6.52, IC50=0.3uM
    BindingDB: IC50=300nM
    8477 4ez7:A (2.49) BS02 2AN 2.7.11.22 GO:0000082 ... P24941 22893598 BindingDB: Kd=37000nM, IC50=91000nM
    8478 4ez7:A (2.49) BS03 2AN 2.7.11.22 GO:0000082 ... P24941 22893598 BindingDB: Kd=37000nM, IC50=91000nM
    8479 4ezj:A (2.67) BS01 0SC 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22672799 PDBbind: -logKd/Ki=8.42, IC50=3.8nM
    BindingDB: IC50=1585nM
    8480 4f08:A (2.82) BS01 1RS 2.7.10.2 GO:0004672 ... O60674 22698084 PDBbind: -logKd/Ki=6.60, Ki=250nM
    BindingDB: Ki=250nM, EC50=>8800nM
    8481 4f08:B (2.82) BS01 1RS 2.7.10.2 GO:0004672 ... O60674 22698084 BindingDB: Ki=250nM, EC50=>8800nM
    8482 4f09:A (2.4) BS01 JAK 2.7.10.2 GO:0004672 ... O60674 22698084 MOAD: Ki=200nM
    PDBbind: -logKd/Ki=6.70, Ki=200nM
    BindingDB: Ki=200nM, EC50=>8200nM
    8483 4f1l:A (1.9) BS01 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 PDBbind: -logKd/Ki=5.12, Kd=7.6uM
    BindingDB: IC50=>20000nM, Kd=7600nM
    8484 4f1l:B (1.9) BS01 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 BindingDB: IC50=>20000nM, Kd=7600nM
    8485 4f1l:C (1.9) BS01 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 BindingDB: IC50=>20000nM, Kd=7600nM
    8486 4f1l:C (1.9) BS02 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 BindingDB: IC50=>20000nM, Kd=7600nM
    8487 4f1l:D (1.9) BS01 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 BindingDB: IC50=>20000nM, Kd=7600nM
    8488 4f1q:A (2.8) BS01 0RZ 2.4.2.- GO:0003950 ... Q460N5 22823910 PDBbind: -logKd/Ki=4.95, Kd=11.2uM
    BindingDB: IC50=>20000nM, Kd=11200nM
    8489 4f1q:B (2.8) BS01 0RZ 2.4.2.- GO:0003950 ... Q460N5 22823910 BindingDB: IC50=>20000nM, Kd=11200nM
    8490 4f22:A (2.06) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=30.26uM
    BindingDB: EC50=40000nM, Ki=5780nM
    8491 4f29:A (1.749) BS01 QUS ? GO:0015276 ... P19492 22512472 MOAD: Ki=0.168uM
    BindingDB: Ki=>10000nM
    8492 4f2o:A (1.912) BS01 QUS ? GO:0015276 ... P19492 22512472 MOAD: Ki=0.042uM
    BindingDB: Ki=>10000nM
    8493 4f2q:A (2.202) BS01 QUS ? GO:0015276 ... P19492 22512472 MOAD: Ki=0.042uM
    BindingDB: Ki=>10000nM
    8494 4f31:B (2.286) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=2.08uM
    BindingDB: EC50=40000nM, Ki=5780nM
    8495 4f31:D (2.286) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=2.08uM
    BindingDB: EC50=40000nM, Ki=5780nM
    8496 4f39:A (1.834) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=3.44uM
    PDBbind: -logKd/Ki=5.70, Ki=1980nM
    BindingDB: EC50=40000nM, Ki=5780nM
    8497 4f3g:A (2.064) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=3.44uM
    BindingDB: EC50=40000nM, Ki=5780nM
    8498 4f3i:A (1.4) BS01 0S6 ? N/A O60885 22645123 MOAD: Kd=36.1nM
    PDBbind: -logKd/Ki=7.44, Kd=36.1nM
    BindingDB: Ki=17nM, IC50=18.2nM
    8499 4f5d:A (3.0) BS01 C2E ? GO:0002218 ... Q86WV6 22728659 BindingDB: EC50=4500nM, Kd=1210nM
    8500 4f5d:B (3.0) BS01 C2E ? GO:0002218 ... Q86WV6 22728659 BindingDB: EC50=4500nM, Kd=1210nM
    8501 4f5p:A (1.85) BS05 F2A 2.7.7.7
    4.2.99.-
    4.2.99.18    		 GO:0001701 ... P06746 22959623 BindingDB: Ki=5000nM
    8502 4f5y:A (2.396) BS02 C2E ? GO:0002218 ... Q86WV6 22728660 Manual survey: Kd=3.7uM (22728660)
    PDBbind: -logKd/Ki=5.43, Kd=3.70uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8503 4f5y:B (2.396) BS01 C2E ? GO:0002218 ... Q86WV6 22728660 Manual survey: Kd=3.7uM (22728660)
    PDBbind: -logKd/Ki=5.43, Kd=3.70uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8504 4f63:A (2.55) BS01 0S7 2.7.10.1 GO:0004672 ... P11362 22612866 PDBbind: -logKd/Ki=6.30, IC50=0.5uM
    BindingDB: IC50=501.19nM
    8505 4f63:B (2.55) BS01 0S7 2.7.10.1 GO:0004672 ... P11362 22612866 BindingDB: IC50=501.19nM
    8506 4f64:A (2.05) BS01 0S8 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=63nM
    PDBbind: -logKd/Ki=7.20, IC50=63.1nM
    BindingDB: IC50=794.33nM
    8507 4f64:B (2.05) BS01 0S8 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=63nM
    BindingDB: IC50=794.33nM
    8508 4f65:A (2.26) BS01 0S9 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=2.5nM
    PDBbind: -logKd/Ki=8.60, IC50=2.5nM
    BindingDB: IC50=63.1nM
    8509 4f65:B (2.26) BS01 0S9 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=2.5nM
    BindingDB: IC50=63.1nM
    8510 4f6v:A (2.3) BS01 ZYM 2.5.1.96 GO:0003824 ... A9JQL9 22662288 MOAD: ic50=24uM
    PDBbind: -logKd/Ki=5.80, IC50=1.6uM
    BindingDB: IC50=24000nM, Ki=250nM
    8511 4f6x:A (1.98) BS01 ZYL 2.5.1.96 GO:0003824 ... A9JQL9 22662288 MOAD: ic50=45.3uM
    PDBbind: -logKd/Ki=5.09, IC50=8.2uM
    BindingDB: IC50=45300nM, Ki=450nM
    8512 4f7v:A (1.73) BS01 J1D 2.7.6.3 GO:0000287 ... P26281 22727779 MOAD: Kd=4.16uM
    PDBbind: -logKd/Ki=5.38, Kd=4.16uM
    BindingDB: IC50=9530nM, Kd=4160nM
    8513 4f9b:A (2.5) BS01 0SY 2.7.11.1 GO:0004672 ... O00311 23064647 BindingDB: IC50=10nM
    8514 4f9b:C (2.5) BS01 0SY 2.7.11.1 GO:0004672 ... O00311 23064647 BindingDB: IC50=10nM
    8515 4f9c:A (2.08) BS01 0SX 2.7.11.1 GO:0004672 ... O00311 23064647 BindingDB: IC50=3.4nM
    8516 4f9g:A (2.95) BS01 C2E ? GO:0002218 ... Q86WV6 22705373 Manual survey: Km=2.4+-0.5mM (22705373)
    PDBbind: -logKd/Ki=5.62, Kd=2.4uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8517 4f9g:C (2.95) BS01 C2E ? GO:0002218 ... Q86WV6 22705373 Manual survey: Km=2.4+-0.5mM (22705373)
    PDBbind: -logKd/Ki=5.62, Kd=2.4uM
    BindingDB: EC50=4500nM, Kd=1210nM
    8518 4f9w:A (2.0) BS01 GG5 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: Ki=600nM, IC50=67nM
    8519 4f9w:A (2.0) BS02 GG5 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: Ki=600nM, IC50=67nM
    8520 4f9w:A (2.0) BS03 LM4 2.7.11.24 GO:0000077 ... Q16539 23840427 MOAD: Ki=114nM
    PDBbind: -logKd/Ki=6.94, Ki=114nM
    BindingDB: IC50=210nM, Ki=110nM
    8521 4f9y:A (1.85) BS01 GG5 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: Ki=600nM, IC50=67nM
    8522 4f9y:A (1.85) BS02 GG5 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: Ki=600nM, IC50=67nM
    8523 4f9y:A (1.85) BS03 LM3 2.7.11.24 GO:0000077 ... Q16539 23840427 MOAD: Ki=184nM
    PDBbind: -logKd/Ki=6.74, Kd=184nM
    BindingDB: IC50=190nM, Ki=180nM
    8524 4fa2:A (2.0) BS01 GG5 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: Ki=600nM, IC50=67nM
    8525 4fa2:A (2.0) BS02 SB0 2.7.11.24 GO:0000077 ... Q16539 23840427 BindingDB: IC50=44nM
    8526 4fa3:A (2.2) BS02 0SL 1.1.1.-
    1.1.1.188
    1.1.1.210
    1.1.1.239
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.1.1.64    		 GO:0001523 ... P42330 22877157 MOAD: ic50=0.032uM
    BindingDB: IC50=32nM
    8527 4fal:A (2.0) BS02 0T0 1.1.1.-
    1.1.1.188
    1.1.1.210
    1.1.1.239
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.1.1.64    		 GO:0001523 ... P42330 22877157 MOAD: ic50=0.05uM
    BindingDB: IC50=50nM
    8528 4fam:A (2.0) BS02 0SZ 1.1.1.-
    1.1.1.188
    1.1.1.210
    1.1.1.239
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.1.1.64    		 GO:0001523 ... P42330 22877157 MOAD: ic50=0.013uM
    BindingDB: IC50=13nM
    8529 4fam:B (2.0) BS02 0SZ 1.1.1.-
    1.1.1.188
    1.1.1.210
    1.1.1.239
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.1.1.64    		 GO:0001523 ... P42330 22877157 MOAD: ic50=0.013uM
    BindingDB: IC50=13nM
    8530 4fbp:A (2.5) BS01 AMP 3.1.3.11 GO:0005737 ... P00636 1850623 BindingDB: IC50=1300nM
    8531 4fbp:B (2.5) BS01 AMP 3.1.3.11 GO:0005737 ... P00636 1850623 BindingDB: IC50=1300nM
    8532 4fbp:C (2.5) BS01 AMP 3.1.3.11 GO:0005737 ... P00636 1850623 BindingDB: IC50=1300nM
    8533 4fbp:D (2.5) BS01 AMP 3.1.3.11 GO:0005737 ... P00636 1850623 BindingDB: IC50=1300nM
    8534 4fc0:A (2.95) BS01 0T2 2.7.11.1 GO:0004672 ... P15056 22883026 PDBbind: -logKd/Ki=7.16, IC50=69nM
    BindingDB: IC50=69nM
    8535 4fc0:B (2.95) BS01 0T2 2.7.11.1 GO:0004672 ... P15056 22883026 BindingDB: IC50=69nM
    8536 4fcd:A (2.02) BS02 0T6 3.1.4.17 GO:0004114 ... Q9Y233 22902656 MOAD: ic50=0.28nM
    PDBbind: -logKd/Ki=9.55, IC50=0.28nM
    BindingDB: IC50=0.28nM
    8537 4fcd:B (2.02) BS02 0T6 3.1.4.17 GO:0004114 ... Q9Y233 22902656 MOAD: ic50=0.28nM
    BindingDB: IC50=0.28nM
    8538 4fco:A (1.76) BS01 0U4 3.4.23.46 GO:0004190 ... P56817 N/A BindingDB: IC50=567nM
    8539 4fdh:A (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8540 4fdh:B (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8541 4fdh:C (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8542 4fdh:D (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8543 4fdh:E (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8544 4fdh:F (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8545 4fdh:G (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8546 4fdh:H (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8547 4fdh:I (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8548 4fdh:J (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8549 4fdh:K (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8550 4fdh:L (2.71) BS02 0T3 1.14.15.4
    1.14.15.5    		 GO:0002017 ... P19099 23322723 BindingDB: IC50=1nM
    8551 4ffw:A (2.9) BS01 715 3.4.14.5 GO:0001618 ... P14740 N/A BindingDB: IC50=26.01nM
    8552 4ffw:B (2.9) BS01 715 3.4.14.5 GO:0001618 ... P14740 N/A BindingDB: IC50=26.01nM
    8553 4fgk:A (1.401) BS02 0TX 1.10.5.1 GO:0001512 ... P16083 N/A BindingDB: IC50=1500nM
    8554 4fgk:A (1.401) BS04 0TX 1.10.5.1 GO:0001512 ... P16083 N/A BindingDB: IC50=1500nM
    8555 4fgk:B (1.401) BS01 0TX 1.10.5.1 GO:0001512 ... P16083 N/A BindingDB: IC50=1500nM
    8556 4fgk:B (1.401) BS02 0TX 1.10.5.1 GO:0001512 ... P16083 N/A BindingDB: IC50=1500nM
    8557 4fgz:A (1.994) BS01 CQA 2.1.1.103 GO:0000139 ... Q8IDQ9 22771008 MOAD: ic50=1350uM
    PDBbind: -logKd/Ki=2.87, IC50=1350uM
    BindingDB: IC50=1350000nM
    8558 4fgz:A (1.994) BS02 CQA 2.1.1.103 GO:0000139 ... Q8IDQ9 22771008 MOAD: ic50=1350uM
    PDBbind: -logKd/Ki=2.87, IC50=1350uM
    BindingDB: IC50=1350000nM
    8559 4fgz:B (1.994) BS01 CQA 2.1.1.103 GO:0000139 ... Q8IDQ9 22771008 MOAD: ic50=1350uM
    BindingDB: IC50=1350000nM
    8560 4fgz:B (1.994) BS02 CQA 2.1.1.103 GO:0000139 ... Q8IDQ9 22771008 MOAD: ic50=1350uM
    BindingDB: IC50=1350000nM
    8561 4fh2:A (1.44) BS03 0RN 3.5.2.6 GO:0008800 ... P0AD64 22974281 BindingDB: Ki=1.5e+3nM, IC50=3.4e+3nM
    8562 4fic:A (2.5) BS01 0UL 2.7.10.2 GO:0004672 ... P00523 23534475 MOAD: ic50=20uM
    PDBbind: -logKd/Ki=4.70, IC50=20uM
    BindingDB: IC50=2.0e+4nM
    8563 4fic:B (2.5) BS01 0UL 2.7.10.2 GO:0004672 ... P00523 23534475 MOAD: ic50=20uM
    BindingDB: IC50=2.0e+4nM
    8564 4fjz:A (3.0) BS01 4FJ 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22876881 PDBbind: -logKd/Ki=6.29, Ki=509nM
    BindingDB: Ki=509nM
    8565 4fk6:A (2.2) BS01 0UJ 2.7.10.2 GO:0004672 ... P23458 23107482 MOAD: Ki=0.2nM
    PDBbind: -logKd/Ki=9.70, Ki=0.2nM
    BindingDB: Ki=3.2nM, EC50=355nM, IC50=1.000nM
    8566 4fk6:B (2.2) BS01 0UJ 2.7.10.2 GO:0004672 ... P23458 23107482 MOAD: Ki=0.2nM
    BindingDB: Ki=3.2nM, EC50=355nM, IC50=1.000nM
    8567 4fki:A (1.6) BS01 09K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: IC50=67nM, Kd=463nM
    8568 4fkk:A (2.6) BS01 BES 3.4.11.2 GO:0001525 ... P15145 23071329 PDBbind: -logKd/Ki=9.30, Ki=0.5nM
    BindingDB: Ki=4100nM, IC50=9400nM
    8569 4fkl:A (1.26) BS01 CK2 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Ki=6500nM, Kd=30300nM, IC50=6.50e+3nM, kon=8.22E+04M-1-s-1, koff=1.42E+00s-1
    8570 4fko:A (1.55) BS01 20K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=777nM, koff=5.62E-02s-1, Ki=100nM, kon=6.02E+05M-1-s-1
    8571 4fkp:A (1.6) BS01 LS5 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=210nM, koff=4.97E-02s-1, kon=175033.3M-1-s-1, IC50=660nM
    8572 4fkq:A (1.75) BS01 42K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=191nM, kon=3.21E+04M-1-s-1, koff=5.00E-03s-1
    8573 4fkr:A (1.9) BS01 45K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: koff=8.20E-03s-1, Kd=35.8nM, kon=9.72E+04M-1-s-1
    8574 4fku:A (1.47) BS01 60K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: koff=1.33E-02s-1, Kd=8.43nM, kon=9.39E+05M-1-s-1
    8575 4fku:A (1.47) BS02 60K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: koff=1.33E-02s-1, Kd=8.43nM, kon=9.39E+05M-1-s-1
    8576 4fkv:A (1.7) BS01 61K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=82.2nM, kon=3.97E+04M-1-s-1, koff=5.00E-03s-1
    8577 4fkw:A (1.8) BS01 62K 2.7.11.22 GO:0000082 ... P24941 N/A BindingDB: Kd=47nM, kon=6.49E+04M-1-s-1, koff=2.61E-03s-1
    8578 4fl6:A (2.55) BS01 UWN ? GO:0005634 ... Q96JM7 23292653 BindingDB: Kd=120nM, IC50=49nM
    8579 4fl6:A (2.55) BS02 UWN ? GO:0005634 ... Q96JM7 23292653 BindingDB: Kd=120nM, IC50=49nM
    8580 4fl6:B (2.55) BS01 UWN ? GO:0005634 ... Q96JM7 23292653 BindingDB: Kd=120nM, IC50=49nM
    8581 4fl6:B (2.55) BS02 UWN ? GO:0005634 ... Q96JM7 23292653 BindingDB: Kd=120nM, IC50=49nM
    8582 4fl7:A (1.85) BS02 BHO 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 22836518 BindingDB: Ki=179000nM
    8583 4flh:A (2.6) BS01 14K 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22897589 PDBbind: -logKd/Ki=9.00, Ki=1nM
    BindingDB: Ki=1nM
    8584 4fli:A (1.55) BS03 Y16 3.4.11.18 GO:0006508 ... P53582 22913487 MOAD: ic50=3.59uM
    PDBbind: -logKd/Ki=5.44, IC50=3.59uM
    BindingDB: IC50=3590nM
    8585 4flk:A (1.47) BS03 Y10 3.4.11.18 GO:0006508 ... P53582 22913487 MOAD: ic50=5.58uM
    PDBbind: -logKd/Ki=5.25, IC50=5.58uM
    BindingDB: IC50=5580nM
    8586 4fm5:A (2.81) BS02 DF0 1.14.99.1 GO:0004601 ... Q05769 22984634 BindingDB: IC50=110nM
    8587 4fm5:B (2.81) BS02 DF0 1.14.99.1 GO:0004601 ... Q05769 22984634 BindingDB: IC50=110nM
    8588 4fm5:C (2.81) BS02 DF0 1.14.99.1 GO:0004601 ... Q05769 22984634 BindingDB: IC50=110nM
    8589 4fm5:D (2.81) BS02 DF0 1.14.99.1 GO:0004601 ... Q05769 22984634 BindingDB: IC50=110nM
    8590 4fmu:A (2.1) BS04 0UM 2.1.1.-
    2.1.1.359    		 GO:0005634 ... Q9BYW2 23043551 MOAD: Kd=360nM
    PDBbind: -logKd/Ki=6.44, Kd=360nM
    BindingDB: IC50=800nM
    8591 4fnz:A (2.6) BS01 NZF 2.7.10.1 GO:0004672 ... Q9UM73 22932897 PDBbind: -logKd/Ki=7.80, IC50=0.016uM
    BindingDB: IC50=16nM
    8592 4fob:A (1.9) BS01 0US 2.7.10.1 GO:0004672 ... Q9UM73 22734674 MOAD: ic50=0.005uM
    PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=5nM
    8593 4foc:A (1.7) BS01 0UU 2.7.10.1 GO:0004672 ... Q9UM73 22734674 MOAD: ic50=0.003uM
    PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=3nM
    8594 4frk:A (2.1) BS01 DWD 3.4.23.46 GO:0004190 ... P56817 22928914 MOAD: ic50=0.008uM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=36nM
    8595 4fs4:A (1.74) BS01 H24 3.4.23.46 GO:0004190 ... P56817 24900403 PDBbind: -logKd/Ki=6.57, Ki=270nM
    BindingDB: IC50=91000nM
    8596 4fs4:B (1.74) BS01 H24 3.4.23.46 GO:0004190 ... P56817 24900403 BindingDB: IC50=91000nM
    8597 4fsn:A (2.1) BS01 A58 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=20nM
    8598 4fsr:A (2.5) BS01 HKC 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=12nM
    8599 4fst:A (1.9) BS01 HK4 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=5nM
    8600 4fsw:A (2.3) BS01 HK6 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=17000nM
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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