Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    3401 2w70:A (1.77) BS01 L22 6.3.4.14 GO:0003824 ... P24182 19413326 MOAD: ic50=12uM
    PDBbind: -logKd/Ki=4.92, IC50=12.0uM
    BindingDB: IC50=12000nM
    3402 2w70:B (1.77) BS01 L22 6.3.4.14 GO:0003824 ... P24182 19413326 MOAD: ic50=12uM
    BindingDB: IC50=12000nM
    3403 2w71:A (1.99) BS01 L23 6.3.4.14 GO:0003824 ... P24182 19413326 MOAD: ic50=0.334uM
    PDBbind: -logKd/Ki=6.48, IC50=0.334uM
    BindingDB: IC50=334nM
    3404 2w71:C (1.99) BS01 L23 6.3.4.14 GO:0003824 ... P24182 19413326 MOAD: ic50=0.334uM
    BindingDB: IC50=334nM
    3405 2w8y:A (1.8) BS01 486 ? N/A P06401 19372222 PDBbind: -logKd/Ki=9.09, Ki=0.82nM
    BindingDB: IC50=0.300000nM, Ki=1.1nM, EC50=>10000nM
    3406 2w8y:B (1.8) BS01 NDR ? N/A P06401 19372222 BindingDB: Kd=0.4nM, Ki=1.9nM, IC50=3.2nM, EC50=2.2nM
    3407 2w9g:A (1.95) BS01 TOP 1.5.1.3 GO:0004146 ... P0A017 19280600 MOAD: Kd=0.97nM
    BindingDB: Ki=3.4nM, IC50=14.4nM
    3408 2w9h:A (1.48) BS01 TOP 1.5.1.3 GO:0004146 ... P0A017 19280600 MOAD: Kd=430nM
    PDBbind: -logKd/Ki=6.37, Kd=430nM
    BindingDB: Ki=3.4nM, IC50=14.4nM
    3409 2w9s:A (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3410 2w9s:B (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3411 2w9s:C (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3412 2w9s:D (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3413 2w9s:E (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3414 2w9s:F (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    3415 2waj:A (2.4) BS01 SNB 2.7.11.24 GO:0004672 ... P53779 19303774 MOAD: ic50=0.398uM
    PDBbind: -logKd/Ki=6.40, IC50=0.398uM
    BindingDB: IC50=398.11nM
    3416 2wbd:A (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    PDBbind: -logKd/Ki=6.64, IC50=0.23uM
    BindingDB: IC50=100nM
    3417 2wbd:B (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3418 2wbd:C (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    PDBbind: -logKd/Ki=6.64, IC50=0.23uM
    BindingDB: IC50=100nM
    3419 2wbd:D (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3420 2wbd:E (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3421 2wbd:F (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3422 2wbd:G (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3423 2wbd:H (2.4) BS01 RO5 3.1.3.11 GO:0000122 ... P09467 19969452 MOAD: ic50=0.23uM
    BindingDB: IC50=100nM
    3424 2wd1:A (2.0) BS01 ZZY 2.7.10.1 GO:0004672 ... P08581 19369077 MOAD: ic50=82nM
    PDBbind: -logKd/Ki=7.09, IC50=82nM
    BindingDB: IC50=82nM
    3425 2wd3:A (1.8) BS01 MS4 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 20148564 MOAD: ic50=86nM
    PDBbind: -logKd/Ki=7.07, IC50=86nM
    BindingDB: IC50=86nM
    3426 2wd3:A (1.8) BS02 MS4 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 20148564 MOAD: ic50=86nM
    PDBbind: -logKd/Ki=7.07, IC50=86nM
    BindingDB: IC50=86nM
    3427 2wd7:A (1.9) BS02 VGD 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Ki=10.6uM
    PDBbind: -logKd/Ki=4.97, Ki=10.6uM
    BindingDB: Ki=10600nM
    3428 2wd7:B (1.9) BS02 VGD 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Ki=10.6uM
    BindingDB: Ki=10600nM
    3429 2wd7:C (1.9) BS02 VGD 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Ki=10.6uM
    BindingDB: Ki=10600nM
    3430 2wd7:D (1.9) BS02 VGD 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Ki=10.6uM
    BindingDB: Ki=10600nM
    3431 2wd8:A (2.1) BS02 VGF 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Kd=10.6uM
    BindingDB: Ki=7nM
    3432 2wd8:B (2.1) BS02 VGF 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Kd=10.6uM
    BindingDB: Ki=7nM
    3433 2wd8:C (2.1) BS01 VGF 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Kd=10.6uM
    BindingDB: Ki=7nM
    3434 2wd8:D (2.1) BS02 VGF 1.5.1.33 GO:0000166 ... O76290 19527033 MOAD: Kd=10.6uM
    BindingDB: Ki=7nM
    3435 2wej:A (1.45) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 19882701 MOAD: Kd=839nM
    PDBbind: -logKd/Ki=6.08, Kd=839nM
    BindingDB: Ki=1103nM, Kd=1149700nM
    3436 2wer:A (1.6) BS01 RDC ? GO:0005524 ... P02829 19236053 MOAD: Kd=90nM
    PDBbind: -logKd/Ki=7.05, Kd=90nM
    BindingDB: IC50=2e+2nM
    3437 2wer:B (1.6) BS01 RDC ? GO:0005524 ... P02829 19236053 MOAD: Kd=90nM
    BindingDB: IC50=2e+2nM
    3438 2wev:A (2.3) BS01 CK7 2.7.11.22 GO:0000082 ... P24941 19472269 PDBbind: -logKd/Ki=8.00, IC50=0.01uM
    BindingDB: IC50=10.0nM, Ki=2nM
    3439 2wev:C (2.3) BS01 CK7 2.7.11.22 GO:0000082 ... P24941 19472269 BindingDB: IC50=10.0nM, Ki=2nM
    3440 2wey:A (2.8) BS01 EV1 3.1.4.17 GO:0004114 ... Q9Y233 19622871 PDBbind: -logKd/Ki=7.12, IC50=76nM
    BindingDB: IC50=36nM
    3441 2wey:B (2.8) BS01 EV1 3.1.4.17 GO:0004114 ... Q9Y233 19622871 BindingDB: IC50=36nM
    3442 2wf0:A (1.6) BS01 ZY0 3.4.23.46 GO:0004190 ... P56817 19428244 MOAD: ic50=0.21uM
    PDBbind: -logKd/Ki=6.68, IC50=0.21uM
    BindingDB: IC50=210nM
    3443 2wf1:A (1.6) BS01 ZY1 3.4.23.46 GO:0004190 ... P56817 19477642 MOAD: ic50=0.002uM
    PDBbind: -logKd/Ki=8.70, IC50=2nM
    BindingDB: IC50=2nM
    3444 2wge:A (1.8) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3445 2wgg:A (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3446 2wgg:B (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3447 2wgg:C (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3448 2wgg:D (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3449 2wgg:E (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3450 2wgg:F (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3451 2wgg:G (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3452 2wgg:H (2.0) BS01 TLM 2.3.1.293 GO:0004315 ... P9WQD9 19604480 BindingDB: Kd=2.260e+5nM
    3453 2wgj:A (2.0) BS01 VGH 2.7.10.1 GO:0004672 ... P08581 21812414 MOAD: Ki=0.002uM
    PDBbind: -logKd/Ki=8.70, Ki=0.002uM
    BindingDB: IC50=8nM, Kd=2.0nM, Ki=2nM
    3454 2wh8:A (1.7) BS02 II2 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=1.08uM
    BindingDB: Kd=4.9e+3nM
    3455 2wh8:B (1.7) BS02 II2 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=1.08uM
    BindingDB: Kd=4.9e+3nM
    3456 2wh8:C (1.7) BS02 II2 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=1.08uM
    BindingDB: Kd=4.9e+3nM
    3457 2wh8:D (1.7) BS02 II2 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=1.08uM
    BindingDB: Kd=4.9e+3nM
    3458 2whf:A (1.58) BS02 II4 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=4.8uM
    BindingDB: Kd=3.26e+4nM
    3459 2whf:A (1.58) BS03 II4 1.14.-.- GO:0004497 ... P9WPN5 19605350 MOAD: Kd=4.8uM
    BindingDB: Kd=3.26e+4nM
    3460 2who:A (2.0) BS03 VGI 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0003723 ... P26663 19877603 MOAD: ic50=0.02uM
    PDBbind: -logKd/Ki=7.70, IC50=20nM
    BindingDB: IC50=20nM, EC50=7100nM
    3461 2who:B (2.0) BS03 VGI 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0003723 ... P26663 19877603 MOAD: ic50=0.02uM
    BindingDB: IC50=20nM, EC50=7100nM
    3462 2wih:A (2.5) BS01 P48 2.7.11.22 GO:0000082 ... P24941 19603809 MOAD: ic50=0.045uM
    PDBbind: -logKd/Ki=7.35, IC50=45nM
    BindingDB: IC50=45nM
    3463 2wih:C (2.5) BS01 P48 2.7.11.22 GO:0000082 ... P24941 19603809 MOAD: ic50=0.045uM
    BindingDB: IC50=45nM
    3464 2wip:A (2.8) BS01 P49 2.7.11.22 GO:0000082 ... P24941 19603809 BindingDB: IC50=3nM
    3465 2wip:C (2.8) BS01 P49 2.7.11.22 GO:0000082 ... P24941 19603809 BindingDB: IC50=3nM
    3466 2wmr:A (2.43) BS01 ZYR 2.7.11.1 GO:0000077 ... O14757 19572549 MOAD: ic50=52uM
    PDBbind: -logKd/Ki=4.28, IC50=52uM
    BindingDB: IC50=52000nM
    3467 2wmu:A (2.6) BS01 ZYU 2.7.11.1 GO:0000077 ... O14757 19572549 PDBbind: -logKd/Ki=4.38, IC50=42uM
    BindingDB: IC50=42000nM
    3468 2wmv:A (2.009) BS01 ZYV 2.7.11.1 GO:0000077 ... O14757 19572549 MOAD: ic50=9.2uM
    PDBbind: -logKd/Ki=5.04, IC50=9.2uM
    BindingDB: IC50=9200nM
    3469 2wmw:A (2.43) BS01 ZYW 2.7.11.1 GO:0000077 ... O14757 19572549 MOAD: ic50=0.39uM
    PDBbind: -logKd/Ki=6.41, IC50=0.39uM
    BindingDB: IC50=390nM
    3470 2wmx:A (2.45) BS01 ZY6 2.7.11.1 GO:0000077 ... O14757 19572549 MOAD: ic50=0.86uM
    PDBbind: -logKd/Ki=6.07, IC50=0.86uM
    BindingDB: IC50=890nM
    3471 2wo8:A (2.0) BS04 077 3.4.24.65 GO:0004222 ... P39900 19703773 MOAD: ic50=0.52uM
    PDBbind: -logKd/Ki=6.28, IC50=0.52uM
    BindingDB: IC50=520nM
    3472 2wo8:C (2.0) BS04 077 3.4.24.65 GO:0004222 ... P39900 19703773 MOAD: ic50=0.52uM
    BindingDB: IC50=520nM
    3473 2wo9:A (1.7) BS04 068 3.4.24.65 GO:0004222 ... P39900 19703773 MOAD: ic50=0.062uM
    PDBbind: -logKd/Ki=7.21, IC50=62nM
    BindingDB: IC50=62nM
    3474 2wo9:C (1.7) BS04 068 3.4.24.65 GO:0004222 ... P39900 19703773 MOAD: ic50=0.062uM
    BindingDB: IC50=62nM
    3475 2wog:A (2.0) BS02 ZZD ? GO:0003777 ... P52732 19793049 BindingDB: IC50=1000nM, EC50=1720nM, Ki=143.8nM
    3476 2wog:B (2.0) BS02 ZZD ? GO:0003777 ... P52732 19793049 BindingDB: IC50=1000nM, EC50=1720nM, Ki=143.8nM
    3477 2wog:C (2.0) BS02 ZZD ? GO:0003777 ... P52732 19793049 BindingDB: IC50=1000nM, EC50=1720nM, Ki=143.8nM
    3478 2wot:A (1.85) BS01 ZZG 2.7.11.30 GO:0004672 ... P36897 19736928 MOAD: ic50=44nM
    PDBbind: -logKd/Ki=7.36, IC50=44nM
    BindingDB: IC50=44nM, EC50=55nM
    3479 2wou:A (2.3) BS01 ZZF 2.7.11.30 GO:0004672 ... P36897 19736928 MOAD: ic50=72nM
    PDBbind: -logKd/Ki=7.14, IC50=72nM
    BindingDB: EC50=22nM, IC50=72nM
    3480 2wqb:A (2.95) BS01 QQ1 2.7.10.1 GO:0004672 ... Q02763 19854647 PDBbind: -logKd/Ki=6.27, IC50=0.54uM
    BindingDB: IC50=540nM
    3481 2wsa:A (1.6) BS02 646 2.3.1.97 GO:0004379 ... Q4Q5S8 20360736 MOAD: Kd=1nM
    BindingDB: Ki=41nM, IC50=2nM
    3482 2wtc:A (3.0) BS01 VGM 2.7.11.1 GO:0004672 ... O96017 20022510 PDBbind: -logKd/Ki=6.51, IC50=0.31uM
    BindingDB: IC50=310nM
    3483 2wtd:A (2.75) BS01 ZZK 2.7.11.1 GO:0004672 ... O96017 20022510 PDBbind: -logKd/Ki=6.68, IC50=0.21uM
    BindingDB: EC50=10000nM
    3484 2wti:A (2.5) BS01 WTI 2.7.11.1 GO:0004672 ... O96017 20022510 MOAD: ic50=0.092uM
    PDBbind: -logKd/Ki=7.04, IC50=92nM
    BindingDB: EC50=5000nM
    3485 2wtj:A (2.1) BS01 WTJ 2.7.11.1 GO:0004672 ... O96017 20022510 MOAD: ic50=0.7uM
    PDBbind: -logKd/Ki=6.15, IC50=0.7uM
    BindingDB: IC50=700nM
    3486 2wtv:A (2.4) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20067443 MOAD: Ki=1.8nM
    PDBbind: -logKd/Ki=8.74, Ki=1.8nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3487 2wtv:B (2.4) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20067443 MOAD: Ki=1.8nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3488 2wtv:C (2.4) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20067443 MOAD: Ki=1.8nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3489 2wtv:D (2.4) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20067443 MOAD: Ki=1.8nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3490 2wtw:A (3.302) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20067443 PDBbind: -logKd/Ki=8.19, Kd=6.5nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3491 2wu6:A (1.92) BS01 DKI 2.7.12.1 GO:0004672 ... P49761 21276940 MOAD: ic50=29.2nM
    PDBbind: -logKd/Ki=7.53, IC50=29.2nM
    BindingDB: IC50=29nM
    3492 2wuz:A (2.35) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    3493 2wuz:B (2.35) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    3494 2wv2:A (2.7) BS01 TPF 1.14.13.70 GO:0004497 ... Q385E8 20386598 BindingDB: Kd=3.4e+2nM
    3495 2wwj:A (2.6) BS02 Y28 1.14.11.66
    1.14.11.69    		 N/A O75164 20088513 PDBbind: -logKd/Ki=4.48, IC50=33uM
    BindingDB: IC50=33000nM
    3496 2wwj:B (2.6) BS02 Y28 1.14.11.66
    1.14.11.69    		 N/A O75164 20088513 BindingDB: IC50=33000nM
    3497 2wx2:A (2.27) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    3498 2wx2:B (2.27) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    3499 2wyf:A (2.4) BS01 MBG ? GO:0005737 ... Q05097 20410292 PDBbind: -logKd/Ki=4.43, Kd=37uM
    BindingDB: Kd=70000nM
    3500 2wyf:C (2.4) BS01 MBG ? GO:0005737 ... Q05097 20410292 BindingDB: Kd=70000nM
    3501 2wyg:A (1.88) BS01 461 3.4.21.6 GO:0004252 ... P00742 20006499 MOAD: Ki=2nM
    PDBbind: -logKd/Ki=8.70, Ki=2nM
    BindingDB: Ki=2nM
    3502 2wyj:A (2.38) BS01 898 3.4.21.6 GO:0004252 ... P00742 20006499 MOAD: Ki=1nM
    PDBbind: -logKd/Ki=9.00, Ki=1nM
    BindingDB: Ki=0.8nM
    3503 2x22:A (2.1) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3504 2x22:B (2.1) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3505 2x23:A (1.807) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3506 2x23:B (1.807) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3507 2x23:E (1.807) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3508 2x23:G (1.807) BS02 TCU 1.3.1.9 GO:0004318 ... P9WGR1 20200152 MOAD: Ki=7.8nM
    BindingDB: Ki=913nM, IC50=51nM
    3509 2x2k:A (2.6) BS01 X2K 2.7.10.1 GO:0004672 ... P07949 20117004 PDBbind: -logKd/Ki=6.52, IC50=0.30uM
    BindingDB: IC50=300nM
    3510 2x2l:A (2.0) BS01 X2L 2.7.10.1 GO:0004672 ... P07949 20117004 MOAD: ic50=5.3uM
    PDBbind: -logKd/Ki=5.28, IC50=5.3uM
    BindingDB: IC50=5300nM
    3511 2x2m:A (2.5) BS01 X2M 2.7.10.1 GO:0004672 ... P07949 20117004 MOAD: ic50=0.17uM
    PDBbind: -logKd/Ki=6.77, IC50=0.17uM
    BindingDB: IC50=170nM
    3512 2x2m:B (2.5) BS01 X2M 2.7.10.1 GO:0004672 ... P07949 20117004 MOAD: ic50=0.17uM
    BindingDB: IC50=170nM
    3513 2x39:A (1.93) BS02 X39 2.7.11.1 GO:0004672 ... P31751 20151677 MOAD: ic50=2.2nM
    PDBbind: -logKd/Ki=8.66, IC50=2.2nM
    BindingDB: IC50=2.2nM
    3514 2x4z:A (2.1) BS01 7KC 2.7.11.1 GO:0004672 ... O96013 20439741 MOAD: Kd=2.7nM
    BindingDB: Ki=15nM, IC50=19nM
    3515 2x6d:A (2.796) BS01 X6D 2.7.11.1 GO:0000212 ... O14965 20565112 PDBbind: -logKd/Ki=7.92, IC50=12nM
    BindingDB: IC50=12nM
    3516 2x6e:A (3.35) BS01 YM4 2.7.11.1 GO:0000212 ... O14965 20565112 PDBbind: -logKd/Ki=7.82, IC50=15nM
    BindingDB: IC50=15nM
    3517 2x7c:A (1.9) BS02 KZ9 ? GO:0003777 ... P52732 20597485 MOAD: ic50=2uM
    PDBbind: -logKd/Ki=5.70, IC50=2uM
    BindingDB: IC50=2000nM
    3518 2x7c:B (1.9) BS03 KZ9 ? GO:0003777 ... P52732 20597485 MOAD: ic50=2uM
    BindingDB: IC50=2000nM
    3519 2x7o:A (3.7) BS01 ZOP 2.7.11.30 GO:0004672 ... P36897 20919678 PDBbind: -logKd/Ki=7.47, IC50=34nM
    BindingDB: EC50=105nM, IC50=34nM
    3520 2x7o:B (3.7) BS01 ZOP 2.7.11.30 GO:0004672 ... P36897 20919678 BindingDB: EC50=105nM, IC50=34nM
    3521 2x7o:C (3.7) BS01 ZOP 2.7.11.30 GO:0004672 ... P36897 20919678 BindingDB: EC50=105nM, IC50=34nM
    3522 2x7o:D (3.7) BS01 ZOP 2.7.11.30 GO:0004672 ... P36897 20919678 BindingDB: EC50=105nM, IC50=34nM
    3523 2x7o:E (3.7) BS01 ZOP 2.7.11.30 GO:0004672 ... P36897 20919678 BindingDB: EC50=105nM, IC50=34nM
    3524 2x7s:A (1.64) BS01 WZC 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 20297840 MOAD: Ki=1660nM
    PDBbind: -logKd/Ki=5.78, Ki=1660nM
    BindingDB: IC50=526nM, Ki=10330nM
    3525 2x7s:A (1.64) BS02 WZC 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 20297840 MOAD: Ki=1660nM
    PDBbind: -logKd/Ki=5.78, Ki=1660nM
    BindingDB: IC50=526nM, Ki=10330nM
    3526 2x7t:A (1.89) BS01 WZB 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 20297840 MOAD: Ki=232nM
    PDBbind: -logKd/Ki=6.63, Ki=232nM
    BindingDB: Ki=232nM, IC50=290nM
    3527 2x81:A (2.91) BS01 ZZL 2.7.11.1 GO:0000212 ... O14965 20426425 PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=34nM, Kd=6.5nM
    3528 2x8d:A (1.9) BS01 X8D 2.7.11.1 GO:0000077 ... O14757 20673630 MOAD: ic50=0.8uM
    PDBbind: -logKd/Ki=6.10, IC50=0.8uM
    BindingDB: IC50=800nM
    3529 2x8e:A (2.5) BS01 X8E 2.7.11.1 GO:0000077 ... O14757 20673630 MOAD: ic50=0.014uM
    PDBbind: -logKd/Ki=7.85, IC50=14nM
    BindingDB: IC50=14nM
    3530 2x9e:A (3.1) BS01 SVE 2.7.12.1 GO:0004672 ... P33981 21159646 PDBbind: -logKd/Ki=6.74, IC50=0.182uM
    BindingDB: IC50=182nM
    3531 2x9f:A (1.75) BS01 X9F 2.7.10.1 GO:0004672 ... P54760 20850301 MOAD: ic50=0.061uM
    PDBbind: -logKd/Ki=7.21, IC50=61nM
    BindingDB: IC50=61nM
    3532 2xa4:A (2.04) BS01 AZ5 2.7.10.2 GO:0004672 ... O60674 21138246 MOAD: ic50<0.003uM
    PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=58nM
    3533 2xa4:B (2.04) BS01 AZ5 2.7.10.2 GO:0004672 ... O60674 21138246 MOAD: ic50<0.003uM
    BindingDB: IC50=58nM
    3534 2xae:A (2.6) BS01 2XA ? GO:0003777 ... P52732 21344920 PDBbind: -logKd/Ki=7.30, Ki<50.0nM
    BindingDB: Ki=200nM, IC50=53.3nM
    3535 2xae:B (2.6) BS01 2XA ? GO:0003777 ... P52732 21344920 BindingDB: Ki=200nM, IC50=53.3nM
    3536 2xae:C (2.6) BS01 2XA ? GO:0003777 ... P52732 21344920 BindingDB: Ki=200nM, IC50=53.3nM
    3537 2xbj:A (2.3) BS01 XBJ 2.7.11.1 GO:0004672 ... O96017 21186793 MOAD: ic50=0.003uM
    PDBbind: -logKd/Ki=8.52, IC50=0.003uM
    BindingDB: IC50=30nM
    3538 2xbv:A (1.66) BS01 XBV 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Kd=3.7nM
    PDBbind: -logKd/Ki=8.43, Kd=3.7nM
    BindingDB: Kd=3.7nM
    3539 2xbw:A (1.72) BS01 455 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Ki=0.01uM
    PDBbind: -logKd/Ki=8.00, Ki=10nM
    BindingDB: Ki=10nM
    3540 2xbx:A (1.85) BS01 RR8 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Ki=0.015uM
    PDBbind: -logKd/Ki=7.82, Ki=15nM
    BindingDB: Ki=15nM
    3541 2xc0:A (2.05) BS01 8NC 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Ki=0.192uM
    PDBbind: -logKd/Ki=6.72, Ki=192nM
    BindingDB: Ki=192nM
    3542 2xc4:A (1.67) BS02 IVK 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Ki=0.009uM
    PDBbind: -logKd/Ki=8.05, Ki=9nM
    BindingDB: Ki=9nM
    3543 2xc5:A (1.7) BS01 OYJ 3.4.21.6 GO:0004252 ... P00742 20650636 MOAD: Ki=0.062uM
    BindingDB: Ki=62nM
    3544 2xdu:A (1.74) BS02 LGA 3.6.4.10 GO:0005524 ... P07900 20718493 BindingDB: Kd=19000000nM
    3545 2xdx:A (2.42) BS01 WOE 3.6.4.10 GO:0005524 ... P07900 20718493 MOAD: Kd=0.35uM
    PDBbind: -logKd/Ki=6.46, Kd=0.35uM
    BindingDB: Ki=1200nM
    3546 2xey:A (2.7) BS01 YVQ 2.7.11.1 GO:0000077 ... O14757 20561787 PDBbind: -logKd/Ki=5.19, IC50=6.5uM
    BindingDB: IC50=154881662nM
    3547 2xez:A (2.25) BS01 XEZ 2.7.11.1 GO:0000077 ... O14757 20561787 MOAD: ic50=1.5uM
    PDBbind: -logKd/Ki=5.82, IC50=1.5uM
    BindingDB: IC50=660693448nM
    3548 2xf0:A (2.4) BS01 4UB 2.7.11.1 GO:0000077 ... O14757 20561787 MOAD: ic50=30uM
    PDBbind: -logKd/Ki=4.52, IC50=30uM
    BindingDB: IC50=33113112nM
    3549 2xfj:A (1.8) BS01 VG5 3.4.23.46 GO:0004190 ... P56817 20579874 MOAD: ic50=13nM
    PDBbind: -logKd/Ki=7.89, IC50=13nM
    BindingDB: IC50=310nM
    3550 2xfp:A (1.66) BS02 ISN 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 BindingDB: IC50=18750nM, Ki=3000nM
    3551 2xfp:B (1.66) BS02 ISN 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 BindingDB: IC50=18750nM, Ki=3000nM
    3552 2xhd:A (1.8) BS02 7T9 ? GO:0015276 ... P42262 20614889 BindingDB: EC50=2500nM
    3553 2xhd:B (1.8) BS02 7T9 ? GO:0015276 ... P42262 20614889 BindingDB: EC50=2500nM
    3554 2xj1:A (2.13) BS01 XJ1 2.7.11.1 GO:0004672 ... P11309 21358046 MOAD: Kd=28nM
    PDBbind: -logKd/Ki=7.55, Kd=28nM
    BindingDB: IC50=13nM
    3555 2xj2:A (2.2) BS01 985 2.7.11.1 GO:0004672 ... P11309 21358046 MOAD: Kd=66nM
    PDBbind: -logKd/Ki=7.18, Kd=66nM
    BindingDB: IC50=57nM
    3556 2xjx:A (1.66) BS01 XJX 3.6.4.10 GO:0005524 ... P07900 20662534 MOAD: Kd=0.71nM
    PDBbind: -logKd/Ki=9.15, Kd=0.71nM
    BindingDB: IC50=20nM
    3557 2xk4:A (2.1) BS01 OL2 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=16.9uM
    PDBbind: -logKd/Ki=4.77, IC50=16.9uM
    BindingDB: IC50=16900nM
    3558 2xk7:A (1.992) BS01 30E 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=1.5uM
    PDBbind: -logKd/Ki=5.82, IC50=1.5uM
    BindingDB: IC50=1500nM
    3559 2xk8:A (2.001) BS01 5R1 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.4uM
    PDBbind: -logKd/Ki=5.62, IC50=2.4uM
    BindingDB: IC50=1300nM
    3560 2xkc:A (2.5) BS01 4VQ 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.6uM
    PDBbind: -logKd/Ki=5.59, IC50=2.6uM
    BindingDB: IC50=2300nM
    3561 2xkd:A (1.96) BS01 T3M 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.3uM
    PDBbind: -logKd/Ki=5.64, IC50=2.3uM
    BindingDB: IC50=1600nM
    3562 2xke:A (2.203) BS01 WI2 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=4.2uM
    PDBbind: -logKd/Ki=5.38, IC50=4.2uM
    BindingDB: IC50=4200nM
    3563 2xkf:A (2.35) BS01 BX1 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=0.87uM
    PDBbind: -logKd/Ki=6.06, IC50=0.87uM
    BindingDB: IC50=410nM
    3564 2xkw:A (2.02) BS01 P1B ? GO:0003677 ... P37231 N/A BindingDB: EC50=250nM, IC50=1700nM, Kd=871nM, Ki=420nM
    3565 2xkw:B (2.02) BS01 P1B ? GO:0003677 ... P37231 N/A BindingDB: EC50=250nM, IC50=1700nM, Kd=871nM, Ki=420nM
    3566 2xm8:A (3.4) BS01 B4W 2.7.11.1 GO:0004672 ... O96017 21186793 PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    BindingDB: IC50=160nM
    3567 2xmy:A (1.9) BS01 CDK 2.7.11.22 GO:0000082 ... P24941 21035734 MOAD: Ki=0.11nM
    PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    BindingDB: Ki=0.11nM
    3568 2xne:A (2.8) BS01 ASH 2.7.11.1 GO:0000212 ... O14965 20833547 PDBbind: -logKd/Ki=6.72, IC50=0.190uM
    BindingDB: IC50=190nM
    3569 2xnm:A (1.85) BS01 WGZ 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=0.16uM
    PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    BindingDB: IC50=25nM
    3570 2xnn:A (2.5) BS01 430 2.7.11.1 GO:0004672 ... P51955 21366329 PDBbind: -logKd/Ki=4.30, IC50>50uM
    BindingDB: IC50=>50000nM
    3571 2xno:A (1.98) BS01 ED8 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=1.18uM
    PDBbind: -logKd/Ki=5.93, IC50=1.18uM
    BindingDB: IC50=1180nM
    3572 2xnp:A (1.98) BS01 WCX 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=0.36uM
    PDBbind: -logKd/Ki=6.44, IC50=0.36uM
    BindingDB: IC50=570nM
    3573 2xp2:A (1.9) BS01 VGH 2.7.10.1 GO:0004672 ... Q9UM73 21812414 PDBbind: -logKd/Ki=9.00, IC50<1.0nM
    BindingDB: IC50=20nM, Ki=8.2nM, EC50=22840nM, Kd=3.3nM
    3574 2xp3:A (2.0) BS01 B21 5.2.1.8 GO:0000413 ... Q13526 20932746 PDBbind: -logKd/Ki=3.00, IC50>1000uM
    BindingDB: IC50=>1000000nM
    3575 2xp7:A (2.0) BS01 4F8 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: Kd=1.7uM
    PDBbind: -logKd/Ki=5.77, Kd=1.7uM
    BindingDB: Kd=1700nM, IC50=1460nM
    3576 2xp8:A (2.1) BS01 4FY 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=15uM
    PDBbind: -logKd/Ki=4.82, IC50=15uM
    BindingDB: IC50=15000nM
    3577 2xpa:A (1.9) BS01 4G5 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=4.1uM
    PDBbind: -logKd/Ki=5.39, IC50=4.1uM
    BindingDB: IC50=4100nM
    3578 2xpb:A (2.0) BS01 4GE 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=2uM
    PDBbind: -logKd/Ki=5.70, IC50=2.0uM
    BindingDB: IC50=2000nM
    3579 2xud:A (2.65) BS01 DME 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=460nM
    3580 2xui:A (2.6) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 PDBbind: -logKd/Ki=15.00, Kd=1.0fM
    BindingDB: Ki=0.410nM, Kd=0.00041nM
    3581 2xui:B (2.6) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3582 2xuj:A (2.65) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3583 2xuj:B (2.65) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3584 2xuk:A (2.75) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3585 2xuk:B (2.75) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3586 2xup:A (2.7) BS02 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 PDBbind: -logKd/Ki=12.39, Kd=0.41pM
    BindingDB: Ki=0.410nM, Kd=0.00041nM
    3587 2xup:B (2.7) BS02 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    3588 2xvd:A (1.7) BS01 AS6 2.7.10.1 GO:0004672 ... P54760 21441027 MOAD: ic50=0.002uM
    PDBbind: -logKd/Ki=8.70, IC50=0.002uM
    BindingDB: IC50=7nM
    3589 2xxt:A (1.9) BS01 KAI ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=8.05, Kd=9.0nM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3590 2xxt:B (1.9) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3591 2xxv:A (1.7) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3592 2xxv:B (1.7) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3593 2xxy:A (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=7.89, Kd=12.9nM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3594 2xxy:B (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3595 2xxy:C (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3596 2xxy:D (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    3597 2xxz:A (1.8) BS01 8XQ 1.14.11.68 N/A O15054 N/A BindingDB: IC50=100nM
    3598 2xxz:B (1.8) BS01 8XQ 1.14.11.68 N/A O15054 N/A BindingDB: IC50=100nM
    3599 2xy9:A (1.97) BS03 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=0.65nM
    PDBbind: -logKd/Ki=9.19, Ki=0.65nM
    BindingDB: Ki=0.65nM
    3600 2xy9:A (1.97) BS04 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=0.65nM
    PDBbind: -logKd/Ki=9.19, Ki=0.65nM
    BindingDB: Ki=0.65nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218