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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    3001 2q93:A (1.6) BS03 B21 3.4.11.18 GO:0004177 ... P0AE18 18093325 MOAD: ic50=0.56uM
    PDBbind: -logKd/Ki=6.25, IC50=0.56uM
    BindingDB: IC50=>200000nM
    3002 2q94:A (1.63) BS03 A04 3.4.11.18 GO:0004177 ... P0AE18 18093325 MOAD: ic50=0.37uM
    PDBbind: -logKd/Ki=6.43, IC50=0.37uM
    BindingDB: IC50=197000nM
    3003 2q95:A (1.7) BS03 A05 3.4.11.18 GO:0004177 ... P0AE18 18093325 MOAD: ic50=1.6uM
    PDBbind: -logKd/Ki=5.80, IC50=1.6uM
    BindingDB: IC50=48600nM
    3004 2q96:A (1.6) BS03 A18 3.4.11.18 GO:0004177 ... P0AE18 18093325 MOAD: ic50=1.2uM
    PDBbind: -logKd/Ki=5.92, IC50=1.2uM
    BindingDB: IC50=158000nM
    3005 2qa6:A (2.6) BS02 KN2 ? N/A P03372 18344977 BindingDB: IC50=48nM, EC50=298nM
    3006 2qa6:B (2.6) BS02 KN2 ? N/A P03372 18344977 BindingDB: IC50=48nM, EC50=298nM
    3007 2qa8:A (1.85) BS02 GEN ? N/A P03372 18344977 PDBbind: -logKd/Ki=6.00, IC50=0.99uM
    BindingDB: IC50=395nM, EC50=240nM, Ki=370nM
    3008 2qa8:B (1.85) BS02 GEN ? N/A P03372 18344977 BindingDB: IC50=395nM, EC50=240nM, Ki=370nM
    3009 2qbp:A (2.5) BS01 527 3.1.3.48 GO:0004725 ... P18031 17705360 MOAD: Ki=0.004uM
    PDBbind: -logKd/Ki=8.40, Ki=0.004uM
    BindingDB: Ki=4nM
    3010 2qbq:A (2.1) BS01 4B3 3.1.3.48 GO:0004725 ... P18031 17705360 MOAD: Ki=0.036uM
    PDBbind: -logKd/Ki=7.44, Ki=0.036uM
    BindingDB: Ki=36nM
    3011 2qbr:A (2.3) BS01 910 3.1.3.48 GO:0004725 ... P18031 17705360 MOAD: Ki=0.47uM
    PDBbind: -logKd/Ki=6.33, Ki=0.47uM
    BindingDB: Ki=470nM
    3012 2qbs:A (2.1) BS01 024 3.1.3.48 GO:0004725 ... P18031 17705360 MOAD: Ki=0.21uM
    PDBbind: -logKd/Ki=6.68, Ki=0.21uM
    BindingDB: Ki=210nM
    3013 2qcf:A (1.22) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 18184586 PDBbind: -logKd/Ki=3.49, IC50=320uM
    BindingDB: Ki=98000nM
    3014 2qd9:A (1.7) BS01 LGF 2.7.11.24 GO:0000077 ... Q16539 17664068 MOAD: ic50=13nM
    PDBbind: -logKd/Ki=7.89, IC50=13nM
    BindingDB: IC50=13nM
    3015 2qe4:A (2.4) BS01 JJ3 ? N/A P03372 17662603 MOAD: Ki=11nM
    PDBbind: -logKd/Ki=7.96, Ki=11.0nM
    BindingDB: Ki=11nM
    3016 2qe4:B (2.4) BS01 JJ3 ? N/A P03372 17662603 MOAD: Ki=11nM
    BindingDB: Ki=11nM
    3017 2qf6:A (3.1) BS01 A56 3.6.4.10 GO:0005524 ... P07900 17630989 PDBbind: -logKd/Ki=6.49, Ki=0.32uM
    BindingDB: Ki=3.2e+2nM, Kd=<1.0e+4nM
    3018 2qf6:B (3.1) BS01 A56 3.6.4.10 GO:0005524 ... P07900 17630989 BindingDB: Ki=3.2e+2nM, Kd=<1.0e+4nM
    3019 2qf6:C (3.1) BS01 A56 3.6.4.10 GO:0005524 ... P07900 17630989 BindingDB: Ki=3.2e+2nM, Kd=<1.0e+4nM
    3020 2qf6:D (3.1) BS01 A56 3.6.4.10 GO:0005524 ... P07900 17630989 BindingDB: Ki=3.2e+2nM, Kd=<1.0e+4nM
    3021 2qfo:A (1.68) BS01 A13 3.6.4.10 GO:0005524 ... P07900 17630989 MOAD: Kd=20uM
    PDBbind: -logKd/Ki=4.70, Kd=20uM
    BindingDB: Ki=1.8e+4nM, Kd=2.0e+4nM
    3022 2qfq:A (1.5) BS01 S3P 2.5.1.19 GO:0003824 ... P0A6D3 17855366 MOAD: ic50=66uM
    BindingDB: Kd=7000nM
    3023 2qfs:A (1.55) BS01 S3P 2.5.1.19 GO:0003824 ... P0A6D3 17855366 MOAD: Ki=5.5uM
    BindingDB: Kd=7000nM
    3024 2qft:A (1.55) BS02 S3P 2.5.1.19 GO:0003824 ... P0A6D3 17855366 MOAD: Ki=5.5uM
    BindingDB: Kd=7000nM
    3025 2qfu:A (1.6) BS02 S3P 2.5.1.19 GO:0003824 ... P0A6D3 17855366 MOAD: Ki=66uM
    BindingDB: Kd=7000nM
    3026 2qhx:A (2.61) BS02 FE1 1.5.1.33 GO:0004155 ... Q01782 18245389 BindingDB: Ki=37nM
    3027 2qhx:B (2.61) BS02 FE1 1.5.1.33 GO:0004155 ... Q01782 18245389 BindingDB: Ki=37nM
    3028 2qhx:C (2.61) BS02 FE1 1.5.1.33 GO:0004155 ... Q01782 18245389 BindingDB: Ki=37nM
    3029 2qhx:D (2.61) BS02 FE1 1.5.1.33 GO:0004155 ... Q01782 18245389 BindingDB: Ki=37nM
    3030 2qiq:A (1.9) BS01 CYV 2.1.1.-
    2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0008233 ... P0C6X7 17855091 MOAD: ic50=80uM
    PDBbind: -logKd/Ki=4.10, IC50=80uM
    BindingDB: IC50=80000nM
    3031 2qis:A (1.8) BS03 RIS 2.5.1.1
    2.5.1.10    		 GO:0004659 ... P14324 N/A BindingDB: IC50=11nM, Ki=82.2nM
    3032 2qjr:A (2.2) BS01 PZF 3.4.14.5 GO:0001618 ... P27487 17822893 MOAD: ic50=6.4nM
    BindingDB: IC50=6.4nM
    3033 2qjr:B (2.2) BS01 PZF 3.4.14.5 GO:0001618 ... P27487 17822893 MOAD: ic50=6.4nM
    BindingDB: IC50=6.4nM
    3034 2qk5:A (2.2) BS01 CS5 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=20nM
    3035 2qk5:B (2.2) BS01 CS5 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=8nM
    BindingDB: IC50=20nM
    3036 2qk8:A (2.4) BS01 MTX 1.5.1.3 GO:0000166 ... Q81R22 17696333 MOAD: ic50~20nM
    PDBbind: -logKd/Ki=7.91, IC50=12.2nM
    BindingDB: IC50=15nM
    3037 2qky:A (3.1) BS01 13Z 3.4.14.5 GO:0001618 ... P27487 17544668 BindingDB: IC50=22nM
    3038 2qky:B (3.1) BS01 13Z 3.4.14.5 GO:0001618 ... P27487 17544668 BindingDB: IC50=22nM
    3039 2qky:C (3.1) BS01 13Z 3.4.14.5 GO:0001618 ... P27487 17544668 BindingDB: IC50=22nM
    3040 2qky:D (3.1) BS01 13Z 3.4.14.5 GO:0001618 ... P27487 17544668 BindingDB: IC50=22nM
    3041 2qlm:A (2.1) BS01 F68 2.4.1.1 GO:0000166 ... P00489 N/A PDBbind: -logKd/Ki=5.64, Ki=2.3uM
    BindingDB: Ki=2300nM
    3042 2qln:A (2.15) BS01 F59 2.4.1.1 GO:0000166 ... P00489 N/A PDBbind: -logKd/Ki=5.43, Ki=3.7uM
    BindingDB: Ki=3700nM
    3043 2qlq:A (2.33) BS01 SR2 2.7.10.2 GO:0004672 ... P00523 18316192 PDBbind: -logKd/Ki=6.63, IC50=236nM
    BindingDB: IC50=>27000nM
    3044 2qlq:A (2.33) BS02 SR2 2.7.10.2 GO:0004672 ... P00523 18316192 PDBbind: -logKd/Ki=6.63, IC50=236nM
    BindingDB: IC50=>27000nM
    3045 2qlq:B (2.33) BS01 SR2 2.7.10.2 GO:0004672 ... P00523 18316192 BindingDB: IC50=>27000nM
    3046 2qmd:A (1.65) BS01 CS7 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=5nM
    PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=150nM
    3047 2qmd:B (1.65) BS01 CS7 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=5nM
    BindingDB: IC50=150nM
    3048 2qmf:A (1.75) BS01 CS9 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=3nM
    PDBbind: -logKd/Ki=8.52, IC50=3nM
    BindingDB: IC50=165nM
    3049 2qmf:B (1.75) BS01 CS9 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=3nM
    BindingDB: IC50=165nM
    3050 2qn1:A (2.401) BS01 0AS 2.4.1.1 GO:0000166 ... P00489 18517260 PDBbind: -logKd/Ki=4.77, IC50=17uM
    BindingDB: IC50=17000nM
    3051 2qn3:A (1.96) BS01 F55 2.4.1.1 GO:0000166 ... P00489 N/A PDBbind: -logKd/Ki=5.36, Ki=4.4uM
    BindingDB: Ki=4400nM
    3052 2qn7:A (1.83) BS02 HBZ 2.4.1.1 GO:0000166 ... P00489 N/A BindingDB: Ki=6300nM
    3053 2qn8:A (1.9) BS02 NBY 2.4.1.1 GO:0000166 ... P00489 N/A BindingDB: Ki=3300nM
    3054 2qn8:A (1.9) BS03 NBY 2.4.1.1 GO:0000166 ... P00489 N/A BindingDB: Ki=3300nM
    3055 2qn9:A (2.0) BS02 NBX 2.4.1.1 GO:0000166 ... P00489 N/A BindingDB: Ki=6000nM
    3056 2qnb:A (1.8) BS01 BZD 2.4.1.1 GO:0000166 ... P00489 N/A PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    3057 2qnb:A (1.8) BS02 BZD 2.4.1.1 GO:0000166 ... P00489 N/A PDBbind: -logKd/Ki=5.34, Ki=4.6uM
    BindingDB: Ki=4600nM
    3058 2qo8:A (1.4) BS02 3CC 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 18161740 MOAD: Ki=3.4nM
    PDBbind: -logKd/Ki=8.47, Ki=3.4nM
    BindingDB: Ki=0.9nM
    3059 2qoa:A (1.6) BS02 MAJ 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 18161740 MOAD: Ki=52nM
    PDBbind: -logKd/Ki=7.28, Ki=52nM
    BindingDB: Ki=52nM
    3060 2qoa:A (1.6) BS03 MAJ 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 18161740 MOAD: Ki=52nM
    PDBbind: -logKd/Ki=7.28, Ki=52nM
    BindingDB: Ki=52nM
    3061 2qoe:A (2.3) BS01 448 3.4.14.5 GO:0001618 ... P27487 17827003 MOAD: ic50=25nM
    PDBbind: -logKd/Ki=7.60, IC50=25nM
    BindingDB: IC50=25nM
    3062 2qoe:B (2.3) BS01 448 3.4.14.5 GO:0001618 ... P27487 17827003 MOAD: ic50=25nM
    BindingDB: IC50=25nM
    3063 2qp8:A (1.5) BS01 SC7 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=106nM
    3064 2qp8:B (1.5) BS01 SC7 3.4.23.46 GO:0004190 ... P56817 18023580 MOAD: ic50=8nM
    BindingDB: IC50=106nM
    3065 2qpk:A (2.34) BS03 SHA 1.11.1.7 GO:0004601 ... P80025 27986533 BindingDB: IC50=4.0e+2nM
    3066 2qpy:A (2.5) BS02 DHT ? N/A P19091 17911242 BindingDB: EC50=3.98nM, IC50=1.000000nM
    3067 2qq7:A (2.38) BS01 SR2 2.7.10.2 GO:0004672 ... P00523 18316192 PDBbind: -logKd/Ki=5.24, IC50=5.71uM
    BindingDB: IC50=>27000nM
    3068 2qq7:B (2.38) BS01 SR2 2.7.10.2 GO:0004672 ... P00523 18316192 BindingDB: IC50=>27000nM
    3069 2qqg:A (2.05) BS04 NCA 2.3.1.286 GO:0017136 ... P53686 17289592 BindingDB: IC50=91000nM
    3070 2qrg:A (1.85) BS01 M07 2.4.1.1 GO:0000166 ... P00489 19781947 MOAD: Ki=6.6uM
    PDBbind: -logKd/Ki=5.18, Ki=6.6uM
    BindingDB: Ki=6600nM
    3071 2qrh:A (1.83) BS01 M08 2.4.1.1 GO:0000166 ... P00489 19781947 MOAD: Ki=19.6uM
    PDBbind: -logKd/Ki=4.71, Ki=19.6uM
    BindingDB: Ki=19600nM
    3072 2qrv:A (2.89) BS01 SAH 2.1.1.-
    2.1.1.37    		 GO:0008168 ... Q9Y6K1 17713477 BindingDB: IC50=>50000nM
    3073 2qrv:D (2.89) BS01 SAH 2.1.1.-
    2.1.1.37    		 GO:0008168 ... Q9Y6K1 17713477 BindingDB: IC50=>50000nM
    3074 2qrv:E (2.89) BS01 SAH 2.1.1.-
    2.1.1.37    		 GO:0008168 ... Q9Y6K1 17713477 BindingDB: IC50=>50000nM
    3075 2qrv:H (2.89) BS01 SAH 2.1.1.-
    2.1.1.37    		 GO:0008168 ... Q9Y6K1 17713477 BindingDB: IC50=>50000nM
    3076 2qry:A (2.25) BS01 TPS ? GO:0015888 ... P31550 18177053 MOAD: Kd=2.3nM
    PDBbind: -logKd/Ki=8.64, Kd=2.3nM
    BindingDB: Kd=2.3nM
    3077 2qry:B (2.25) BS01 TPS ? GO:0015888 ... P31550 18177053 MOAD: Kd=2.3nM
    BindingDB: Kd=2.3nM
    3078 2qry:C (2.25) BS01 TPS ? GO:0015888 ... P31550 18177053 MOAD: Kd=2.3nM
    BindingDB: Kd=2.3nM
    3079 2qry:D (2.25) BS01 TPS ? GO:0015888 ... P31550 18177053 MOAD: Kd=2.3nM
    BindingDB: Kd=2.3nM
    3080 2qs1:A (1.8) BS01 UB1 ? GO:0015276 ... P22756 20558186 MOAD: Kd=33nM
    BindingDB: Kd=10nM
    3081 2qs1:B (1.8) BS01 UB1 ? GO:0015276 ... P22756 20558186 MOAD: Kd=33nM
    BindingDB: Kd=10nM
    3082 2qs2:A (1.8) BS01 UBF ? GO:0015276 ... P22756 20558186 MOAD: Kd=186nM
    BindingDB: Kd=25nM
    3083 2qs2:B (1.8) BS01 UBF ? GO:0015276 ... P22756 20558186 MOAD: Kd=186nM
    BindingDB: Kd=25nM
    3084 2qs3:A (1.76) BS01 UBE ? GO:0015276 ... P22756 18789344 MOAD: Kd=1.4nM
    BindingDB: Kd=12nM
    3085 2qs3:B (1.76) BS01 UBE ? GO:0015276 ... P22756 18789344 MOAD: Kd=1.4nM
    BindingDB: Kd=12nM
    3086 2qt9:A (2.1) BS01 524 3.4.14.5 GO:0001618 ... P27487 17851076 MOAD: ic50=0.0023uM
    PDBbind: -logKd/Ki=8.64, IC50=2.3nM
    BindingDB: IC50=2.3nM
    3087 2qt9:B (2.1) BS01 524 3.4.14.5 GO:0001618 ... P27487 17851076 MOAD: ic50=0.0023uM
    BindingDB: IC50=2.3nM
    3088 2qtb:A (2.25) BS01 474 3.4.14.5 GO:0001618 ... P27487 17851076 MOAD: ic50=4.8nM
    PDBbind: -logKd/Ki=8.32, IC50=4.8nM
    BindingDB: IC50=4.8nM
    3089 2qtb:B (2.25) BS01 474 3.4.14.5 GO:0001618 ... P27487 17851076 MOAD: ic50=4.8nM
    BindingDB: IC50=4.8nM
    3090 2qtu:A (2.53) BS01 3AS ? GO:0003677 ... Q92731 17804226 PDBbind: -logKd/Ki=9.28, Ki=0.53nM
    BindingDB: Ki=0.53nM
    3091 2qtu:B (2.53) BS01 3AS ? GO:0003677 ... Q92731 17804226 BindingDB: Ki=0.53nM
    3092 2qu2:A (2.6) BS01 251 3.4.23.46 GO:0004190 ... P56817 17761418 PDBbind: -logKd/Ki=5.43, IC50=3.7uM
    BindingDB: IC50=3700nM
    3093 2qu3:A (2.0) BS01 462 3.4.23.46 GO:0004190 ... P56817 17761418 MOAD: ic50=0.59uM
    PDBbind: -logKd/Ki=6.23, IC50=0.59uM
    BindingDB: IC50=590nM
    3094 2qu5:A (2.95) BS01 276 2.7.10.1 GO:0004672 ... P35968 17696416 PDBbind: -logKd/Ki=8.06, Ki=8.7nM
    BindingDB: Ki=9nM
    3095 2qu6:A (2.1) BS01 857 2.7.10.1 GO:0004672 ... P35968 17696416 MOAD: Ki=3nM
    PDBbind: -logKd/Ki=8.52, Ki=3nM
    BindingDB: IC50=4.6nM, Ki=2.8nM
    3096 2qu6:B (2.1) BS01 857 2.7.10.1 GO:0004672 ... P35968 17696416 MOAD: Ki=3nM
    BindingDB: IC50=4.6nM, Ki=2.8nM
    3097 2qwc:A (1.6) BS02 DAN 3.2.1.18 GO:0004308 ... P03472 9655825 MOAD: Ki=280uM
    PDBbind: -logKd/Ki=3.55, Ki=280uM
    BindingDB: IC50=13000nM
    3098 2qwx:A (1.5) BS03 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3099 2qwx:A (1.5) BS04 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3100 2qwx:B (1.5) BS01 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3101 2qwx:B (1.5) BS04 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3102 2qx4:A (1.65) BS02 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3103 2qx4:B (1.65) BS01 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3104 2qx4:B (1.65) BS03 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3105 2qx6:A (1.75) BS02 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3106 2qx6:A (1.75) BS04 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3107 2qx6:B (1.75) BS01 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3108 2qx6:B (1.75) BS03 ML1 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=1.4uM
    BindingDB: IC50=11300nM, Ki=57nM
    3109 2qx8:A (1.6) BS02 ML2 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=0.7uM
    BindingDB: IC50=1100nM, Ki=6.5nM
    3110 2qx8:B (1.6) BS02 ML2 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=0.7uM
    BindingDB: IC50=1100nM, Ki=6.5nM
    3111 2qx9:A (2.31) BS02 ML2 1.10.5.1 GO:0001512 ... P16083 18254726 MOAD: Kd=0.7uM
    BindingDB: IC50=1100nM, Ki=6.5nM
    3112 2qx9:B (2.31) BS01 ML2 1.10.5.1 GO:0001512 ... P16083 18254726 BindingDB: IC50=1100nM, Ki=6.5nM
    3113 2qx9:B (2.31) BS02 ML2 1.10.5.1 GO:0001512 ... P16083 18254726 BindingDB: IC50=1100nM, Ki=6.5nM
    3114 2qxs:A (1.7) BS01 RAL ? N/A P03372 20924370 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    3115 2qxs:B (1.7) BS01 RAL ? N/A P03372 20924370 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    3116 2qxw:A (0.8) BS02 LDT 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 18250329 BindingDB: IC50=30nM
    3117 2qyk:A (2.1) BS01 NPV 3.1.4.53 GO:0004114 ... P27815 17727341 MOAD: ic50=3.3uM
    PDBbind: -logKd/Ki=5.48, IC50=3.3uM
    BindingDB: IC50=3300nM, EC50=20nM
    3118 2qyk:B (2.1) BS01 NPV 3.1.4.53 GO:0004114 ... P27815 17727341 MOAD: ic50=3.3uM
    BindingDB: IC50=3300nM, EC50=20nM
    3119 2qyl:A (1.95) BS03 NPV 3.1.4.53 GO:0004114 ... Q07343 17727341 MOAD: ic50=0.65uM
    PDBbind: -logKd/Ki=6.19, IC50=0.65uM
    BindingDB: IC50=650nM
    3120 2qyn:A (1.57) BS01 NPV 3.1.4.53 GO:0004114 ... Q08499 17727341 MOAD: ic50=0.57uM
    PDBbind: -logKd/Ki=6.24, IC50=0.57uM
    BindingDB: IC50=1nM
    3121 2qyn:B (1.57) BS01 NPV 3.1.4.53 GO:0004114 ... Q08499 17727341 MOAD: ic50=0.57uM
    BindingDB: IC50=1nM
    3122 2qzl:A (1.8) BS01 IXS 3.4.23.46 GO:0004190 ... P56817 16690314 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=8nM
    3123 2qzo:A (1.72) BS02 KN1 ? N/A P03372 20924370 BindingDB: IC50=1300nM
    3124 2qzo:B (1.72) BS02 KN1 ? N/A P03372 20924370 BindingDB: IC50=1300nM
    3125 2r0u:A (1.9) BS01 M54 2.7.11.1 GO:0000077 ... O14757 17900896 MOAD: ic50=1nM
    PDBbind: -logKd/Ki=9.00, IC50=1.0nM
    BindingDB: IC50=1nM
    3126 2r24:A (1.752) BS02 LDT 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 18250329 BindingDB: IC50=30nM
    3127 2r3r:A (1.47) BS01 6SC 2.7.11.22 GO:0000082 ... P24941 17937404 BindingDB: IC50=20nM
    3128 2r64:A (2.3) BS01 740 2.7.11.22 GO:0000082 ... P24941 18353638 MOAD: ic50=0.03uM
    PDBbind: -logKd/Ki=7.52, IC50=0.03uM
    BindingDB: IC50=30nM
    3129 2r6y:A (2.0) BS01 LLC ? N/A P03372 18474858 MOAD: Ki=0.32nM
    PDBbind: -logKd/Ki=9.49, Ki=0.32nM
    BindingDB: IC50=120nM
    3130 2r6y:B (2.0) BS01 LLC ? N/A P03372 18474858 MOAD: Ki=0.32nM
    BindingDB: IC50=120nM
    3131 2r7b:A (2.7) BS02 253 2.7.11.1 GO:0004672 ... O15530 17941624 PDBbind: -logKd/Ki=7.22, IC50=0.06uM
    BindingDB: IC50=60nM
    3132 2r8q:A (1.5) BS02 IBM 3.1.4.- GO:0004114 ... Q6S996 17944832 MOAD: ic50=580uM
    PDBbind: -logKd/Ki=3.24, IC50=580uM
    BindingDB: IC50=580000nM
    3133 2r9m:A (1.97) BS01 Y11 3.4.22.27 GO:0006508 ... P25774 N/A PDBbind: -logKd/Ki=8.82, IC50=1.5nM
    BindingDB: IC50=1.5nM
    3134 2r9m:B (1.97) BS01 Y11 3.4.22.27 GO:0006508 ... P25774 N/A BindingDB: IC50=1.5nM
    3135 2r9s:A (2.4) BS01 255 2.7.11.24 GO:0004672 ... P53779 17911023 MOAD: ic50=0.15uM
    PDBbind: -logKd/Ki=6.82, IC50=0.15uM
    BindingDB: IC50=150nM
    3136 2r9s:B (2.4) BS01 255 2.7.11.24 GO:0004672 ... P53779 17911023 MOAD: ic50=0.15uM
    BindingDB: IC50=150nM
    3137 2r9w:A (1.8) BS01 23C 3.5.2.6 GO:0008800 ... P00811 18333608 MOAD: Ki=8uM
    PDBbind: -logKd/Ki=5.10, Ki=8uM
    BindingDB: Ki=5000nM
    3138 2r9w:B (1.8) BS01 23C 3.5.2.6 GO:0008800 ... P00811 18333608 MOAD: Ki=8uM
    BindingDB: Ki=5000nM
    3139 2ra0:A (2.3) BS01 JNJ 3.4.21.6 GO:0004252 ... P00742 18159923 MOAD: Ki=15.9nM
    PDBbind: -logKd/Ki=7.80, Ki=15.9nM
    BindingDB: Ki=15.9nM
    3140 2rah:A (2.0) BS01 11P 2.5.1.1
    2.5.1.10    		 GO:0004659 ... P14324 N/A BindingDB: IC50=629.5nM
    3141 2rcw:A (2.8) BS01 AAI 2.4.2.-
    2.4.2.30    		 GO:0003950 ... P09874 N/A PDBbind: -logKd/Ki=8.10, Ki=8nM
    BindingDB: Ki=8nM, EC50=3nM
    3142 2rd6:A (2.3) BS01 78P 2.4.2.-
    2.4.2.30    		 GO:0003950 ... P09874 N/A PDBbind: -logKd/Ki=8.30, Ki=5nM
    BindingDB: IC50=1.5nM, Ki=5nM, EC50=5.9nM, Kd=1.7nM
    3143 2rdt:A (1.95) BS02 2RD 1.1.3.15
    1.2.3.5    		 GO:0001561 ... Q9UJM8 18215067 MOAD: Ki~15nM
    BindingDB: Ki=15nM
    3144 2rew:A (2.35) BS02 REW ? GO:0003677 ... Q07869 N/A BindingDB: IC50=360nM, EC50=70nM
    3145 2rfi:A (1.59) BS06 SAH 2.1.1.-
    2.1.1.367    		 GO:0002039 ... Q9H9B1 20084102 BindingDB: IC50=230nM
    3146 2rfi:B (1.59) BS02 SAH 2.1.1.-
    2.1.1.367    		 GO:0002039 ... Q9H9B1 20084102 BindingDB: IC50=230nM
    3147 2rfn:A (2.5) BS01 AM7 2.7.10.1 GO:0004672 ... P08581 18055465 MOAD: ic50=5nM
    PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=8.9nM, Ki=8.9nM
    3148 2rfn:B (2.5) BS01 AM7 2.7.10.1 GO:0004672 ... P08581 18055465 MOAD: ic50=5nM
    BindingDB: IC50=8.9nM, Ki=8.9nM
    3149 2rg5:A (2.4) BS01 279 2.7.11.24 GO:0000077 ... Q16539 18072718 MOAD: ic50=3.1nM
    PDBbind: -logKd/Ki=8.51, IC50=3.1nM
    BindingDB: IC50=3.1nM, EC50=61nM
    3150 2rg6:A (1.72) BS01 287 2.7.11.24 GO:0000077 ... Q16539 18072718 MOAD: ic50=2.2nM
    PDBbind: -logKd/Ki=8.66, IC50=2.2nM
    BindingDB: IC50=2.2nM, EC50=10nM
    3151 2rg6:A (1.72) BS02 287 2.7.11.24 GO:0000077 ... Q16539 18072718 MOAD: ic50=2.2nM
    PDBbind: -logKd/Ki=8.66, IC50=2.2nM
    BindingDB: IC50=2.2nM, EC50=10nM
    3152 2rgu:A (2.6) BS01 356 3.4.14.5 GO:0001618 ... P27487 18052023 BindingDB: IC50=1nM, Kd=5.3nM
    3153 2rgu:B (2.6) BS01 356 3.4.14.5 GO:0001618 ... P27487 18052023 BindingDB: IC50=1nM, Kd=5.3nM
    3154 2rip:A (2.9) BS01 34Q 3.4.14.5 GO:0001618 ... P27487 17977724 PDBbind: -logKd/Ki=7.19, IC50=65nM
    BindingDB: IC50=65nM
    3155 2rjp:A (2.8) BS05 886 3.4.24.82 GO:0004222 ... O75173 18042673 PDBbind: -logKd/Ki=7.00, IC50=0.1uM
    BindingDB: IC50=100nM
    3156 2rjp:B (2.8) BS05 886 3.4.24.82 GO:0004222 ... O75173 18042673 BindingDB: IC50=100nM
    3157 2rjp:C (2.8) BS05 886 3.4.24.82 GO:0004222 ... O75173 18042673 BindingDB: IC50=100nM
    3158 2rjp:D (2.8) BS05 886 3.4.24.82 GO:0004222 ... O75173 18042673 BindingDB: IC50=100nM
    3159 2rku:A (1.95) BS02 R78 2.7.11.21 GO:0004672 ... P53350 18005335 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.30, IC50=5.0nM
    BindingDB: IC50=0.830000nM, Kd=0.190000nM, Ki=<1nM
    3160 2rl5:A (2.65) BS01 2RL 2.7.10.1 GO:0004672 ... P35968 18311900 PDBbind: -logKd/Ki=8.40, IC50=4nM
    BindingDB: IC50=0.5nM
    3161 2rox:A (2.0) BS01 T44 ? GO:0005179 ... P02766 15299640 PDBbind: -logKd/Ki=4.98, IC50=10.5uM
    BindingDB: IC50=10500nM
    3162 2rox:B (2.0) BS01 T44 ? GO:0005179 ... P02766 15299640 PDBbind: -logKd/Ki=4.98, IC50=10.5uM
    BindingDB: IC50=10500nM
    3163 2rtd:B (1.65) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3164 2rtd:D (1.65) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3165 2rte:B (1.5) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3166 2rte:D (1.5) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3167 2rtf:B (1.47) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3168 2rtf:D (1.47) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3169 2rtg:B (1.39) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3170 2rtg:D (1.39) BS01 BTN ? GO:0009374 ... P22629 9405158 BindingDB: Kd=1.000000nM
    3171 2std:A (2.1) BS01 CRP 4.2.1.94 GO:0005575 ... P56221 9665698 MOAD: Kd=0.14nM
    PDBbind: -logKd/Ki=9.85, Ki=0.14nM
    BindingDB: Ki=30nM
    3172 2tcl:A (2.2) BS05 RO4 3.4.24.7 GO:0004222 ... P03956 7656013 MOAD: ic50=9nM
    BindingDB: IC50=40nM
    3173 2tdd:A (2.7) BS02 UFP 2.1.1.45 GO:0004799 ... P00469 8343503 BindingDB: Ki=14nM, Kd=10nM
    3174 2tmn:E (1.6) BS06 0FA 3.4.24.27 GO:0004222 ... P00800 3709536 MOAD: Ki=1.3uM
    PDBbind: -logKd/Ki=5.89, Ki=1.3uM
    BindingDB: Ki=21300nM, Kd=1288nM
    3175 2uuo:A (2.5) BS01 LK3 6.3.2.9 GO:0005515 ... P14900 19007109 MOAD: ic50=170uM
    PDBbind: -logKd/Ki=3.77, IC50=170uM
    BindingDB: IC50=170000nM
    3176 2uup:A (1.88) BS01 LK4 6.3.2.9 GO:0005515 ... P14900 19007109 MOAD: ic50=105uM
    PDBbind: -logKd/Ki=3.98, IC50=105uM
    BindingDB: IC50=105000nM
    3177 2uv0:E (1.8) BS01 OHN ? N/A P25084 17363368 BindingDB: EC50=139nM
    3178 2uv0:F (1.8) BS01 OHN ? N/A P25084 17363368 BindingDB: EC50=139nM
    3179 2uv0:G (1.8) BS01 OHN ? N/A P25084 17363368 BindingDB: EC50=139nM
    3180 2uv0:H (1.8) BS01 OHN ? N/A P25084 17363368 BindingDB: EC50=139nM
    3181 2uvm:A (1.94) BS01 GVF 2.7.11.1 N/A P31749 17432822 PDBbind: -logKd/Ki=7.10, Ki=0.08uM
    BindingDB: Ki=80nM
    3182 2uw9:A (2.1) BS02 GVP 2.7.11.1 GO:0004672 ... P31751 17451234 BindingDB: IC50=18nM
    3183 2uwl:A (1.9) BS01 895 3.4.21.6 GO:0004252 ... P00742 17420122 MOAD: Ki=4nM
    PDBbind: -logKd/Ki=8.40, Ki=4nM
    BindingDB: Ki=4nM
    3184 2uwo:A (1.75) BS01 701 3.4.21.6 GO:0004252 ... P00742 17420122 MOAD: Ki=2nM
    PDBbind: -logKd/Ki=8.70, Ki=2nM
    BindingDB: Ki=2nM
    3185 2uwp:A (1.75) BS01 894 3.4.21.6 GO:0004252 ... P00742 17420122 MOAD: Ki=154nM
    PDBbind: -logKd/Ki=6.81, Ki=154nM
    BindingDB: Ki=154nM
    3186 2uy3:A (1.9) BS01 H33 3.2.1.14 GO:0004553 ... P29029 17524989 MOAD: Ki=600uM
    PDBbind: -logKd/Ki=3.22, Ki=600uM
    BindingDB: Ki=340000nM
    3187 2uy4:A (1.75) BS01 AZM 3.2.1.14 GO:0004553 ... P29029 17524989 MOAD: Ki=21uM
    PDBbind: -logKd/Ki=4.68, Ki=21uM
    BindingDB: Ki=21000nM
    3188 2uy5:A (1.6) BS01 H35 3.2.1.14 GO:0004553 ... P29029 17524989 MOAD: Ki=3.2uM
    PDBbind: -logKd/Ki=5.49, Ki=3.2uM
    BindingDB: Ki=3200nM
    3189 2uyi:A (2.1) BS02 K02 ? GO:0003777 ... P52732 17498954 MOAD: ic50=0.48uM
    PDBbind: -logKd/Ki=6.32, IC50=0.48uM
    BindingDB: IC50=480nM
    3190 2uyi:B (2.1) BS02 K02 ? GO:0003777 ... P52732 17498954 MOAD: ic50=0.48uM
    BindingDB: IC50=480nM
    3191 2uym:A (2.11) BS02 K03 ? GO:0003777 ... P52732 17498954 MOAD: ic50=3.1uM
    PDBbind: -logKd/Ki=5.51, IC50=3.1uM
    BindingDB: IC50=3100nM
    3192 2uym:B (2.11) BS02 K03 ? GO:0003777 ... P52732 17498954 MOAD: ic50=3.1uM
    BindingDB: IC50=3100nM
    3193 2uzb:A (2.7) BS01 C75 2.7.11.22 GO:0000082 ... P24941 17570665 PDBbind: -logKd/Ki=6.92, IC50=0.12uM
    BindingDB: IC50=120nM
    3194 2uzb:C (2.7) BS01 C75 2.7.11.22 GO:0000082 ... P24941 17570665 BindingDB: IC50=120nM
    3195 2uzd:A (2.72) BS01 C85 2.7.11.22 GO:0000082 ... P24941 17570665 PDBbind: -logKd/Ki=6.74, IC50=0.18uM
    BindingDB: IC50=180nM
    3196 2uzd:C (2.72) BS01 C85 2.7.11.22 GO:0000082 ... P24941 17570665 BindingDB: IC50=180nM
    3197 2uze:A (2.4) BS01 C95 2.7.11.22 GO:0000082 ... P24941 17570665 MOAD: ic50=47uM
    PDBbind: -logKd/Ki=4.33, IC50=47uM
    BindingDB: IC50=47000nM
    3198 2uze:C (2.4) BS01 C95 2.7.11.22 GO:0000082 ... P24941 17570665 MOAD: ic50=47uM
    BindingDB: IC50=47000nM
    3199 2uzl:A (2.4) BS01 C94 2.7.11.22 GO:0000082 ... P24941 17570665 MOAD: ic50=0.61uM
    PDBbind: -logKd/Ki=6.21, IC50=0.61uM
    BindingDB: IC50=610nM
    3200 2uzl:C (2.4) BS01 C94 2.7.11.22 GO:0000082 ... P24941 17570665 MOAD: ic50=0.61uM
    BindingDB: IC50=610nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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