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●I-TASSER ●D-I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●D-QUARK ●DRfold ●DRfold2 ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred ●TCRfinder

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●DeepMSA2 ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP Library
Download all results in tab-seperated text for 19354 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    2001 2bxd:A (3.05) BS01 RWF ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1.2E4nM
    2002 2bxd:B (3.05) BS01 RWF ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1.2E4nM
    2003 2bxe:A (2.95) BS01 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2004 2bxe:A (2.95) BS02 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2005 2bxe:A (2.95) BS03 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2006 2bxe:B (2.95) BS01 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2007 2bxe:B (2.95) BS02 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2008 2bxe:B (2.95) BS03 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2009 2bxf:A (2.95) BS01 DZP ? GO:0003677 ... P02768 16169013 BindingDB: Kd=24547nM
    2010 2bxf:B (2.95) BS01 DZP ? GO:0003677 ... P02768 16169013 BindingDB: Kd=24547nM
    2011 2bxg:A (2.7) BS01 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    2012 2bxg:A (2.7) BS02 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    2013 2bxg:B (2.7) BS01 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    2014 2bxg:B (2.7) BS02 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    2015 2bxk:A (2.4) BS01 IMN ? GO:0003677 ... P02768 16169013 BindingDB: Kd=700nM, Ki=15135612484362nM
    2016 2bxm:A (2.5) BS01 IMN ? GO:0003677 ... P02768 16169013 BindingDB: Kd=700nM, Ki=15135612484362nM
    2017 2bxm:A (2.5) BS02 IMN ? GO:0003677 ... P02768 16169013 BindingDB: Kd=700nM, Ki=15135612484362nM
    2018 2bxq:A (2.6) BS01 IMN ? GO:0003677 ... P02768 16169013 BindingDB: Kd=700nM, Ki=15135612484362nM
    2019 2bxq:A (2.6) BS03 IMN ? GO:0003677 ... P02768 16169013 BindingDB: Kd=700nM, Ki=15135612484362nM
    2020 2bxr:A (3.0) BS02 MLG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 16129825 BindingDB: IC50=4.5nM, Ki=12nM
    2021 2bxr:B (3.0) BS02 MLG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 16129825 BindingDB: IC50=4.5nM, Ki=12nM
    2022 2bxs:A (3.15) BS02 MLG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 16129825 BindingDB: IC50=4.5nM, Ki=12nM
    2023 2bxs:B (3.15) BS02 MLG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 16129825 BindingDB: IC50=4.5nM, Ki=12nM
    2024 2bxv:A (2.15) BS02 3FT 1.3.5.2 GO:0004151 ... Q02127 16480261 MOAD: ic50=280nM
    BindingDB: IC50=280nM
    2025 2byq:A (3.4) BS01 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2026 2byq:A (3.4) BS02 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2027 2byq:B (3.4) BS01 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2028 2byq:C (3.4) BS01 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2029 2byq:C (3.4) BS02 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2030 2byq:D (3.4) BS01 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2031 2byq:D (3.4) BS02 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2032 2byq:E (3.4) BS01 EPJ ? GO:0004888 ... Q8WSF8 16193063 BindingDB: Ki=7.4nM
    2033 2bz6:H (1.6) BS01 346 3.4.21.21 GO:0004252 ... P08709 16621574 MOAD: Ki=0.081uM
    PDBbind: -logKd/Ki=7.09, Ki=0.081uM
    BindingDB: Ki=88nM
    2034 2c0o:A (2.85) BS01 L2G 2.7.10.2 GO:0004672 ... P08631 16216497 PDBbind: -logKd/Ki=5.91, IC50=1.22uM
    BindingDB: IC50=1220nM
    2035 2c0o:B (2.85) BS01 L2G 2.7.10.2 GO:0004672 ... P08631 16216497 BindingDB: IC50=1220nM
    2036 2c1a:A (1.95) BS02 I5S 2.7.11.11 GO:0001669 ... P00517 16249095 MOAD: ic50=0.17uM
    PDBbind: -logKd/Ki=6.77, IC50=0.17uM
    BindingDB: IC50=170nM
    2037 2c1b:A (2.0) BS02 CQP 2.7.11.11 GO:0001669 ... P00517 16249095 MOAD: ic50=0.4uM
    PDBbind: -logKd/Ki=6.40, IC50=0.40uM
    BindingDB: IC50=400nM
    2038 2c3i:B (1.9) BS02 IYZ 2.7.11.1 GO:0004672 ... P11309 17638903 MOAD: Kd=25nM
    PDBbind: -logKd/Ki=7.60, Kd=25nM
    BindingDB: IC50=61nM, Kd=25nM
    2039 2c3j:A (2.1) BS01 DBQ 2.7.11.1 GO:0000077 ... O14757 16289938 MOAD: Ki=0.659uM
    PDBbind: -logKd/Ki=6.18, Ki=0.659uM
    BindingDB: IC50=725nM
    2040 2c3k:A (2.6) BS01 ABO 2.7.11.1 GO:0000077 ... O14757 16289938 PDBbind: -logKd/Ki=7.59, Ki=0.026uM
    BindingDB: IC50=42nM, Ki=26nM
    2041 2c3l:A (2.35) BS01 IDZ 2.7.11.1 GO:0000077 ... O14757 16289938 MOAD: Ki=8.58uM
    PDBbind: -logKd/Ki=5.07, Ki=8.58uM
    BindingDB: Ki=8580nM, IC50=6296nM
    2042 2c4f:H (1.72) BS02 GIL 3.4.21.21 GO:0004252 ... P08709 16289811 PDBbind: -logKd/Ki=7.70, IC50=20nM
    BindingDB: IC50=20nM
    2043 2c57:A (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 PDBbind: -logKd/Ki=3.43, Ki=370uM
    BindingDB: Kd=370000nM
    2044 2c57:B (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 PDBbind: -logKd/Ki=3.43, Ki=370uM
    BindingDB: Kd=370000nM
    2045 2c57:C (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2046 2c57:D (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2047 2c57:E (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2048 2c57:F (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2049 2c57:G (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2050 2c57:H (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2051 2c57:I (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2052 2c57:J (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2053 2c57:K (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2054 2c57:L (3.1) BS01 FA1 4.2.1.10 GO:0003855 ... Q48255 16480265 BindingDB: Kd=370000nM
    2055 2c58:A (2.3) BS01 ETM 3.1.1.7 GO:0001507 ... P04058 16763558 BindingDB: IC50=4.4nM
    2056 2c5f:A (2.6) BS02 CHH 3.1.1.7 GO:0001507 ... P04058 16763558 BindingDB: IC50=8.5nM
    2057 2c5g:A (1.95) BS01 ETM 3.1.1.7 GO:0001507 ... P04058 16763558 BindingDB: IC50=4.4nM
    2058 2c5g:A (1.95) BS02 ETM 3.1.1.7 GO:0001507 ... P04058 16763558 BindingDB: IC50=4.4nM
    2059 2c5n:A (2.1) BS01 CK8 2.7.11.22 GO:0000082 ... P24941 16492568 MOAD: ic50=0.22uM
    PDBbind: -logKd/Ki=6.66, IC50=0.22uM
    BindingDB: IC50=2.2e+2nM, Ki=220nM
    2060 2c5n:C (2.1) BS01 CK8 2.7.11.22 GO:0000082 ... P24941 16492568 MOAD: ic50=0.22uM
    BindingDB: IC50=2.2e+2nM, Ki=220nM
    2061 2c5o:A (2.1) BS01 CK2 2.7.11.22 GO:0000082 ... P24941 16492568 MOAD: ic50=6.5uM
    PDBbind: -logKd/Ki=5.19, IC50=6.50uM
    BindingDB: Ki=6500nM, Kd=30300nM, IC50=6.50e+3nM, kon=8.22E+04M-1-s-1, koff=1.42E+00s-1
    2062 2c5o:C (2.1) BS01 CK2 2.7.11.22 GO:0000082 ... P24941 16492568 MOAD: ic50=6.5uM
    BindingDB: Ki=6500nM, Kd=30300nM, IC50=6.50e+3nM, kon=8.22E+04M-1-s-1, koff=1.42E+00s-1
    2063 2c5v:A (2.9) BS01 CK4 2.7.11.22 GO:0000082 ... P24941 16492568 BindingDB: IC50=2.9e+2nM, Ki=290nM
    2064 2c5v:C (2.9) BS01 CK4 2.7.11.22 GO:0000082 ... P24941 16492568 BindingDB: IC50=2.9e+2nM, Ki=290nM
    2065 2c67:A (1.7) BS02 RM1 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16366596 MOAD: Ki=17uM
    BindingDB: Ki=17000nM
    2066 2c67:B (1.7) BS02 RM1 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16366596 MOAD: Ki=17uM
    BindingDB: Ki=17000nM
    2067 2c69:A (2.1) BS01 CT8 2.7.11.22 GO:0000082 ... P24941 16325401 MOAD: ic50=26uM
    PDBbind: -logKd/Ki=4.59, IC50=26uM
    BindingDB: IC50=26000nM
    2068 2c6e:A (2.1) BS01 HPM 2.7.11.1 GO:0000212 ... O14965 16337122 PDBbind: -logKd/Ki=9.10, IC50=0.8nM
    BindingDB: IC50=0.80nM
    2069 2c6e:B (2.1) BS01 HPM 2.7.11.1 GO:0000212 ... O14965 16337122 BindingDB: IC50=0.80nM
    2070 2c6i:A (1.8) BS01 DT1 2.7.11.22 GO:0000082 ... P24941 16325401 MOAD: ic50=11uM
    PDBbind: -logKd/Ki=4.96, IC50=11uM
    BindingDB: IC50=11000nM
    2071 2c6k:A (1.9) BS01 DT2 2.7.11.22 GO:0000082 ... P24941 16325401 MOAD: ic50=0.73uM
    PDBbind: -logKd/Ki=6.14, IC50=0.73uM
    BindingDB: IC50=730nM
    2072 2c6l:A (2.3) BS01 DT4 2.7.11.22 GO:0000082 ... P24941 16325401 MOAD: ic50=0.27uM
    PDBbind: -logKd/Ki=6.57, IC50=0.27uM
    BindingDB: IC50=270nM
    2073 2c6m:A (1.9) BS01 DT5 2.7.11.22 GO:0000082 ... P24941 16325401 MOAD: ic50=0.35uM
    PDBbind: -logKd/Ki=6.46, IC50=0.35uM
    BindingDB: IC50=350nM
    2074 2c6n:A (3.0) BS02 LPR 3.4.15.1 GO:0006508 ... P12821 16476442 PDBbind: -logKd/Ki=6.88, Ki=131.5nM
    BindingDB: IC50=1.2nM
    2075 2c6n:B (3.0) BS02 LPR 3.4.15.1 GO:0006508 ... P12821 16476442 BindingDB: IC50=1.2nM
    2076 2c6o:A (2.1) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 16325401 PDBbind: -logKd/Ki=8.22, Ki=6nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    2077 2c6t:A (2.61) BS01 DT5 2.7.11.22 GO:0000082 ... P24941 16325401 BindingDB: IC50=350nM
    2078 2c6t:C (2.61) BS01 DT5 2.7.11.22 GO:0000082 ... P24941 16325401 BindingDB: IC50=350nM
    2079 2c72:A (2.0) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2080 2c72:B (2.0) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2081 2c73:A (2.2) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2082 2c73:B (2.2) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2083 2c75:A (1.7) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2084 2c75:B (1.7) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2085 2c76:A (1.7) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2086 2c76:B (1.7) BS02 RSA 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 16605246 BindingDB: Ki=127000nM
    2087 2c88:A (3.1) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 16710301 BindingDB: Kd=0.200000nM, IC50=0.2nM
    2088 2c8k:A (2.8) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 16710301 BindingDB: Kd=0.200000nM, IC50=0.2nM
    2089 2c8l:A (3.1) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 16710301 BindingDB: Kd=0.200000nM, IC50=0.2nM
    2090 2c8x:B (2.17) BS03 C5M 3.4.21.5 GO:0004252 ... P00734 16480269 MOAD: ic50=220nM
    PDBbind: -logKd/Ki=6.66, IC50=220nM
    BindingDB: IC50=220nM
    2091 2c8y:B (2.2) BS03 C3M 3.4.21.5 GO:0004252 ... P00734 16480269 PDBbind: -logKd/Ki=4.00, IC50=100uM
    BindingDB: IC50=100000nM
    2092 2c8z:B (2.14) BS03 C2A 3.4.21.5 GO:0004252 ... P00734 16480269 MOAD: ic50>1mM
    BindingDB: IC50=300000nM
    2093 2c90:B (2.25) BS03 C1M 3.4.21.5 GO:0004252 ... P00734 16480269 MOAD: ic50=330uM
    PDBbind: -logKd/Ki=3.48, IC50=330uM
    BindingDB: IC50=330000nM
    2094 2c93:B (2.2) BS03 C4M 3.4.21.5 GO:0004252 ... P00734 16480269 MOAD: ic50=12uM
    PDBbind: -logKd/Ki=4.92, IC50=12uM
    BindingDB: IC50=12000nM
    2095 2ca2:A (1.9) BS02 SCN 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 3151020 BindingDB: Ki=1600000nM
    2096 2cgf:A (2.2) BS01 P2N ? GO:0005524 ... P02829 17114002 MOAD: Kd=0.39uM
    PDBbind: -logKd/Ki=6.41, Kd=0.39uM
    BindingDB: IC50=1.2e+2nM
    2097 2cgv:A (2.6) BS01 3B3 2.7.11.1 GO:0000077 ... O14757 16574416 PDBbind: -logKd/Ki=4.56, IC50=27.3uM
    BindingDB: IC50=27300nM
    2098 2cgx:A (2.2) BS01 3D3 2.7.11.1 GO:0000077 ... O14757 16574416 MOAD: ic50=15.6uM
    PDBbind: -logKd/Ki=4.81, IC50=15.6uM
    BindingDB: IC50=15600nM
    2099 2chz:A (2.6) BS01 093 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 16647110 PDBbind: -logKd/Ki=7.80, IC50=16nM
    BindingDB: IC50=16nM, Ki=7.0nM
    2100 2cji:A (2.1) BS02 GSK 3.4.21.6 GO:0004252 ... P00742 16697194 MOAD: Ki=6nM
    PDBbind: -logKd/Ki=8.22, Ki=6nM
    BindingDB: Ki=6nM
    2101 2clx:A (1.8) BS01 F18 2.7.11.22 GO:0000082 ... P24941 17064068 PDBbind: -logKd/Ki=4.88, Ki=13.3uM
    BindingDB: IC50=69000nM
    2102 2cm7:A (2.1) BS01 IZD 3.1.3.48 GO:0004725 ... P18031 16916797 MOAD: ic50=210nM
    PDBbind: -logKd/Ki=6.68, IC50=210nM
    BindingDB: IC50=190nM, Ki=180nM
    2103 2cmc:A (2.2) BS01 DFM 3.1.3.48 GO:0004725 ... P18031 16916797 MOAD: ic50=1750nM
    PDBbind: -logKd/Ki=5.76, IC50=1.75uM
    BindingDB: IC50=1750nM
    2104 2cn8:A (2.7) BS02 DBQ 2.7.11.1 GO:0004672 ... O96017 16794575 PDBbind: -logKd/Ki=5.46, IC50=3.5uM
    BindingDB: IC50=183nM
    2105 2cne:A (1.8) BS01 DFJ 3.1.3.48 GO:0004725 ... P18031 17028182 MOAD: ic50=1.7nM
    PDBbind: -logKd/Ki=8.77, IC50=1.7nM
    BindingDB: Ki=1.7nM
    2106 2cnf:A (2.2) BS01 F32 3.1.3.48 GO:0004725 ... P18031 17028182 MOAD: ic50=240nM
    PDBbind: -logKd/Ki=6.62, IC50=240nM
    BindingDB: IC50=270nM
    2107 2cvd:A (1.45) BS02 HQL 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 16547010 MOAD: Kd=0.8uM
    PDBbind: -logKd/Ki=6.10, Kd=0.8uM
    BindingDB: IC50=3800nM
    2108 2cvd:B (1.45) BS02 HQL 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 16547010 MOAD: Kd=0.8uM
    BindingDB: IC50=3800nM
    2109 2cvd:C (1.45) BS02 HQL 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 16547010 MOAD: Kd=0.8uM
    BindingDB: IC50=3800nM
    2110 2cvd:D (1.45) BS02 HQL 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 16547010 MOAD: Kd=0.8uM
    BindingDB: IC50=3800nM
    2111 2d06:A (2.3) BS02 EST 2.8.2.1 GO:0004062 ... P50225 16221673 MOAD: Ki=83.2uM
    PDBbind: -logKd/Ki=4.08, Ki=83.2uM
    BindingDB: Kd=1200nM
    2112 2d06:B (2.3) BS02 EST 2.8.2.1 GO:0004062 ... P50225 16221673 MOAD: Ki=83.2uM
    BindingDB: Kd=1200nM
    2113 2d0t:A (2.3) BS02 PIM 1.13.11.52 GO:0002376 ... P14902 16477023 BindingDB: IC50=48000nM
    2114 2d0t:B (2.3) BS02 PIM 1.13.11.52 GO:0002376 ... P14902 16477023 BindingDB: IC50=48000nM
    2115 2d82:A (-1.00) BS01 TTR 2.3.1.-
    2.3.1.48    		 GO:0004402 ... Q92793 16426974 BindingDB: Kd=19600nM
    2116 2dc6:A (2.3) BS01 73V 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=9100nM
    2117 2dc8:A (1.94) BS01 59A 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=24000nM
    2118 2dc9:A (1.94) BS01 74M 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=68000nM
    2119 2dca:A (2.11) BS01 75V 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=23nM
    2120 2dcc:A (1.93) BS01 77B 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=46000nM
    2121 2dcd:A (2.5) BS01 78A 3.4.22.1 GO:0006508 ... P07688 N/A BindingDB: IC50=29nM
    2122 2ddy:A (-1.00) BS05 MDW 3.4.24.23 GO:0004222 ... P09237 N/A BindingDB: IC50=3162nM
    2123 2dg3:A (1.7) BS01 RAP 5.2.1.8 GO:0000413 ... P62942 12600203 BindingDB: IC50=0.600000nM, EC50=30nM, Ki=0.20nM
    2124 2dg4:A (1.7) BS01 RAP 5.2.1.8 GO:0000413 ... P62942 12600203 BindingDB: IC50=0.600000nM, EC50=30nM, Ki=0.20nM
    2125 2dg9:A (1.7) BS01 RAP 5.2.1.8 GO:0000413 ... P62942 12600203 BindingDB: IC50=0.600000nM, EC50=30nM, Ki=0.20nM
    2126 2drc:A (1.9) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 1932031 MOAD: Kd=0.13nM
    PDBbind: -logKd/Ki=9.89, Kd=0.13nM
    BindingDB: IC50=8.8nM, EC50=1nM
    2127 2drc:B (1.9) BS01 MTX 1.5.1.3 GO:0004146 ... P0ABQ4 1932031 MOAD: Kd=0.13nM
    PDBbind: -logKd/Ki=9.89, Kd=0.13nM
    BindingDB: IC50=8.8nM, EC50=1nM
    2128 2ds1:A (2.0) BS01 1CD 2.7.11.22 GO:0000082 ... P24941 16876403 MOAD: ic50=3.4nM
    PDBbind: -logKd/Ki=8.47, IC50=3.4nM
    BindingDB: IC50=3.4nM
    2129 2duv:A (2.2) BS01 371 2.7.11.22 GO:0000082 ... P24941 17178224 MOAD: ic50=0.087uM
    PDBbind: -logKd/Ki=7.06, IC50=0.087uM
    BindingDB: IC50=87nM
    2130 2dux:A (1.6) BS02 ZST 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=3.1nM, Ki=19nM
    2131 2duz:A (1.6) BS02 ZST 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=3.1nM, Ki=19nM
    2132 2dv0:A (1.62) BS02 ZST 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=3.1nM, Ki=19nM
    2133 2dy5:A (2.7) BS02 224 1.14.14.18 GO:0001525 ... P06762 17253780 BindingDB: IC50=2800nM
    2134 2e2b:A (2.2) BS01 406 2.7.10.2 GO:0004672 ... P00519 17376680 MOAD: ic50=11nM
    PDBbind: -logKd/Ki=7.96, IC50=11nM
    BindingDB: IC50=4.0nM
    2135 2e2b:B (2.2) BS01 406 2.7.10.2 GO:0004672 ... P00519 17376680 MOAD: ic50=11nM
    BindingDB: IC50=4.0nM
    2136 2e2r:A (1.6) BS01 2OH ? N/A P62508 17761695 MOAD: Kd=5.5nM
    PDBbind: -logKd/Ki=8.26, Kd=5.5nM
    BindingDB: IC50=13.1nM
    2137 2e4v:A (2.4) BS01 2CG ? GO:0004930 ... P31422 17360426 BindingDB: EC50=300nM
    2138 2e4v:B (2.4) BS01 2CG ? GO:0004930 ... P31422 17360426 BindingDB: EC50=300nM
    2139 2e4x:A (2.75) BS01 C5B ? GO:0004930 ... P31422 17360426 BindingDB: EC50=8000nM
    2140 2e4x:B (2.75) BS01 C5B ? GO:0004930 ... P31422 17360426 BindingDB: EC50=8000nM
    2141 2e4y:A (3.4) BS01 52A ? GO:0004930 ... P31422 17360426 BindingDB: EC50=1700nM
    2142 2e4y:B (3.4) BS01 52A ? GO:0004930 ... P31422 17360426 BindingDB: EC50=1700nM
    2143 2e91:A (2.14) BS03 ZOL 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.59, Ki=0.26uM
    BindingDB: IC50=6.6e+2nM, Ki=260nM
    2144 2e91:B (2.14) BS03 ZOL 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 BindingDB: IC50=6.6e+2nM, Ki=260nM
    2145 2e92:A (2.31) BS03 M0N 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.89, Ki=0.13uM
    BindingDB: IC50=340nM, Ki=130nM
    2146 2e92:B (2.31) BS03 M0N 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.89, Ki=0.13uM
    BindingDB: IC50=340nM, Ki=130nM
    2147 2e93:A (2.12) BS01 B29 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    BindingDB: Ki=110nM, IC50=280nM
    2148 2e93:A (2.12) BS02 B29 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    BindingDB: Ki=110nM, IC50=280nM
    2149 2e93:B (2.12) BS01 B29 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    BindingDB: Ki=110nM, IC50=280nM
    2150 2e93:B (2.12) BS02 B29 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    BindingDB: Ki=110nM, IC50=280nM
    2151 2e95:A (2.2) BS03 B75 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 BindingDB: IC50=200nM, Ki=80nM
    2152 2e95:B (2.2) BS03 B75 2.5.1.-
    2.5.1.1
    2.5.1.10
    2.5.1.29    		 GO:0004161 ... Q12051 17535895 PDBbind: -logKd/Ki=7.10, Ki=0.08uM
    BindingDB: IC50=200nM, Ki=80nM
    2153 2e9n:A (2.5) BS01 76A 2.7.11.1 GO:0000077 ... O14757 17287122 MOAD: ic50=6.2nM
    PDBbind: -logKd/Ki=8.21, IC50=6.2nM
    BindingDB: EC50=>10000nM, IC50=4nM
    2154 2e9o:A (2.1) BS01 A58 2.7.11.1 GO:0000077 ... O14757 17287122 MOAD: ic50=20nM
    PDBbind: -logKd/Ki=7.70, IC50=20nM
    BindingDB: IC50=20nM
    2155 2e9p:A (2.6) BS01 77A 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=22nM
    2156 2e9u:A (2.0) BS01 A25 2.7.11.1 GO:0000077 ... O14757 N/A PDBbind: -logKd/Ki=8.10, Ki=7.94nM
    BindingDB: IC50=10nM
    2157 2e9v:A (2.0) BS01 85A 2.7.11.1 GO:0000077 ... O14757 N/A PDBbind: -logKd/Ki=7.90, Ki=12.59nM
    BindingDB: IC50=13nM
    2158 2e9v:B (2.0) BS01 85A 2.7.11.1 GO:0000077 ... O14757 N/A BindingDB: IC50=13nM
    2159 2ea2:A (2.5) BS03 F77 3.4.11.18 GO:0006508 ... P50579 17350258 MOAD: ic50=0.016uM
    PDBbind: -logKd/Ki=7.80, IC50=16nM
    BindingDB: IC50=16nM
    2160 2ea4:A (2.35) BS03 F79 3.4.11.18 GO:0006508 ... P50579 17350258 MOAD: ic50=0.046uM
    PDBbind: -logKd/Ki=7.34, IC50=46nM
    BindingDB: IC50=46nM
    2161 2ear:A (3.1) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 17389383 BindingDB: Kd=0.200000nM, IC50=0.2nM
    2162 2eat:A (2.9) BS01 TG1 7.2.2.10 GO:0000166 ... P04191 17389383 BindingDB: Kd=0.200000nM, IC50=0.2nM
    2163 2egh:A (2.2) BS02 FOM 1.1.1.267 GO:0008299 ... P45568 17554164 MOAD: Ki=38nM
    BindingDB: IC50=30nM
    2164 2egh:B (2.2) BS02 FOM 1.1.1.267 GO:0008299 ... P45568 17554164 MOAD: Ki=38nM
    BindingDB: IC50=30nM
    2165 2ei6:A (2.3) BS03 D92 3.4.21.6 GO:0004252 ... P00742 17555959 MOAD: ic50=16nM
    PDBbind: -logKd/Ki=7.39, IC50=41nM
    BindingDB: IC50=16nM
    2166 2ei7:A (2.3) BS03 D93 3.4.21.6 GO:0004252 ... P00742 N/A MOAD: ic50=16nM
    BindingDB: IC50=13nM
    2167 2ei8:A (2.1) BS03 DT8 3.4.21.6 GO:0004252 ... P00742 N/A BindingDB: IC50=2.3nM, Ki=2.85nM
    2168 2esm:A (3.2) BS01 M77 2.7.11.1 GO:0004672 ... Q13464 16249185 BindingDB: Ki=530nM, IC50=180nM
    2169 2esm:B (3.2) BS01 M77 2.7.11.1 GO:0004672 ... Q13464 16249185 BindingDB: Ki=530nM, IC50=180nM
    2170 2etk:A (2.96) BS01 HFS 2.7.11.1 GO:0004672 ... Q13464 16249185 PDBbind: -logKd/Ki=6.82, Ki=0.15uM
    BindingDB: Ki=150nM
    2171 2etk:B (2.96) BS01 HFS 2.7.11.1 GO:0004672 ... Q13464 16249185 BindingDB: Ki=150nM
    2172 2etm:A (2.3) BS01 7PY 2.7.10.2 GO:0004672 ... Q05397 N/A PDBbind: -logKd/Ki=6.67, IC50=0.212uM
    BindingDB: IC50=200nM
    2173 2etm:B (2.3) BS01 7PY 2.7.10.2 GO:0004672 ... Q05397 N/A BindingDB: IC50=200nM
    2174 2etr:A (2.6) BS01 Y27 2.7.11.1 GO:0004672 ... Q13464 16249185 PDBbind: -logKd/Ki=6.82, Ki=0.15uM
    BindingDB: Ki=150nM, IC50=200nM
    2175 2etr:B (2.6) BS01 Y27 2.7.11.1 GO:0004672 ... Q13464 16249185 BindingDB: Ki=150nM, IC50=200nM
    2176 2euf:B (3.0) BS01 LQQ 2.7.11.22 GO:0000082 ... Q00534 16789739 PDBbind: -logKd/Ki=7.82, IC50=15nM
    BindingDB: IC50=16nM, Ki=27nM
    2177 2eva:A (2.0) BS01 ADN 2.7.11.25 GO:0000287 ... O43318 16289117 BindingDB: Kd=4400nM
    2178 2evc:A (1.6) BS03 FC3 3.4.11.18 GO:0004177 ... P0AE18 16552144 MOAD: ic50=0.29uM
    PDBbind: -logKd/Ki=6.54, IC50=0.29uM
    BindingDB: IC50=158000nM
    2179 2evm:A (1.7) BS03 FC2 3.4.11.18 GO:0004177 ... P0AE18 16552144 MOAD: ic50=0.693uM
    PDBbind: -logKd/Ki=6.16, IC50=0.693uM
    BindingDB: IC50=84000nM
    2180 2ewn:A (2.8) BS01 BTX 6.3.4.15 GO:0000976 ... P06709 16438984 BindingDB: Ki=87nM, Kd=1.5nM
    2181 2ewn:B (2.8) BS01 BTX 6.3.4.15 GO:0000976 ... P06709 16438984 BindingDB: Ki=87nM, Kd=1.5nM
    2182 2ewp:A (2.3) BS01 TXF ? N/A P62508 16307879 MOAD: ic50=0.079uM
    PDBbind: -logKd/Ki=7.10, IC50=0.079uM
    BindingDB: IC50=77nM
    2183 2ewp:B (2.3) BS01 TXF ? N/A P62508 16307879 MOAD: ic50=0.079uM
    BindingDB: IC50=77nM
    2184 2ewp:C (2.3) BS01 TXF ? N/A P62508 16307879 MOAD: ic50=0.079uM
    BindingDB: IC50=77nM
    2185 2ewp:D (2.3) BS01 TXF ? N/A P62508 16307879 MOAD: ic50=0.079uM
    BindingDB: IC50=77nM
    2186 2ewp:E (2.3) BS01 TXF ? N/A P62508 16307879 MOAD: ic50=0.079uM
    BindingDB: IC50=77nM
    2187 2exc:X (2.75) BS01 JNK 2.7.11.24 GO:0004672 ... P53779 N/A PDBbind: -logKd/Ki=6.63, IC50=235nM
    BindingDB: IC50=235nM
    2188 2f01:A (0.85) BS01 BTN ? GO:0009374 ... P22629 16699183 MOAD: Kd~0.1pM
    PDBbind: -logKd/Ki=13.00, Kd=0.1pM
    BindingDB: Kd=1.000000nM
    2189 2f01:B (0.85) BS01 BTN ? GO:0009374 ... P22629 16699183 MOAD: Kd~0.1pM
    BindingDB: Kd=1.000000nM
    2190 2f0y:A (2.7) BS01 FPP 2.5.1.58
    2.5.1.59    		 GO:0004659 ... P49354 N/A BindingDB: Kd=2.0nM
    2191 2f0y:B (2.7) BS03 3MN 2.5.1.58 GO:0003824 ... P49356 N/A BindingDB: IC50=0.09nM
    2192 2f0z:A (2.8) BS01 ZMR 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A PDBbind: -logKd/Ki=4.77, Ki=0.017mM
    BindingDB: IC50=7800nM, Ki=5700nM
    2193 2f10:A (2.9) BS01 BCZ 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A PDBbind: -logKd/Ki=3.48, Ki=0.33mM
    BindingDB: Ki=56000nM, IC50=70000nM
    2194 2f14:A (1.71) BS03 FL1 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 16787097 MOAD: Kd=0.64nM
    PDBbind: -logKd/Ki=9.19, Kd=0.64nM
    BindingDB: Ki=45nM
    2195 2f1g:A (1.9) BS01 GNF 3.4.22.27 GO:0006508 ... P25774 16446091 MOAD: Ki=0.029uM
    PDBbind: -logKd/Ki=7.54, Ki=29nM
    BindingDB: Ki=29nM
    2196 2f1g:B (1.9) BS01 GNF 3.4.22.27 GO:0006508 ... P25774 16446091 MOAD: Ki=0.029uM
    BindingDB: Ki=29nM
    2197 2f25:A (1.95) BS01 DAN 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A BindingDB: Ki=25000nM, IC50=37000nM
    2198 2f25:B (1.95) BS01 DAN 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A BindingDB: Ki=25000nM, IC50=37000nM
    2199 2f27:A (2.15) BS01 DAN 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A BindingDB: Ki=25000nM, IC50=37000nM
    2200 2f27:B (2.15) BS01 DAN 3.2.1.18 GO:0004308 ... Q9Y3R4 N/A BindingDB: Ki=25000nM, IC50=37000nM
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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