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I-TASSER QUARK LOMETS COACH COFACTOR MUSTER SEGMER FG-MD ModRefiner REMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom EvoDesign GPCR-I-TASSER

TM-score TM-align MMalign NWalign EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW CASP7 CASP8 CASP9 CASP10 CASP11

Download BioLiP database
The template library files for protien function prediction by COACH and COFACTOR.
You can use this script download_lib.pl for easy download of all function library files.


TM-SITE library

  • pocket.tar.bz2 (template binding pocket structure files)
  • BSITES.bsr (binding site residues)
  • BSITES.fasta (template fasta sequences)
  • BSITES.center (coordinates of binding pocket centers)

    S-SITE library

  • PSSM.tar.bz2 (emplate sequence profiles with binding site information)
  • BSITES.bsr (binding site residues)
  • BSITES.fasta (template fasta sequences)
  • BSITES.fpt (template ligand fingerprints)

    COFACTOR library

  • receptor.tar.bz2 (receptor structure files)
  • ligand.tar.bz2 (ligand structure files)
  • Enzyme.tar.bz2 (EC library files)
  • GO.tar.bz2 (GO library files)
  • map.tar.bz2 (the mapping between ligand-binding, EC and GO templates)



  • Reference:
    Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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