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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL110751
Molecular formula	C15H14F3N3O
IUPAC name	2,2,2-trifluoro-N-[5-(1H-imidazol-5-yl)-5,6,7,8-tetrahydronaphthalen-1-yl]acetamide
Molecular weight	309.292
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.0
Synonyms	SCHEMBL7098608
Inchi Key	WNIQCRWLPXLGQD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H14F3N3O/c16-15(17,18)14(22)21-12-6-2-3-9-10(12)4-1-5-11(9)13-7-19-8-20-13/h2-3,6-8,11H,1,4-5H2,(H,19,20)(H,21,22)
PubChem CID	9944467
ChEMBL	CHEMBL110751
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
377608	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
377613	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
377612	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
377614	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
377607	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
377609	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
377611	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
377610	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453

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