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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	PD165929
Molecular formula	C37H47N5O2
IUPAC name	(2S)-2-[[2,6-di(propan-2-yl)phenyl]carbamoylamino]-3-(1H-indol-3-yl)-2-methyl-N-[(1-pyridin-2-ylcyclohexyl)methyl]propanamide
Molecular weight	593.816
Hydrogen bond acceptor	3
Hydrogen bond donor	4
XlogP	7.7
Synonyms	(2S)-2-[[2,6-di(propan-2-yl)phenyl]carbamoylamino]-3-(1H-indol-3-yl)-2-methyl-N-[(1-pyridin-2-ylcyclohexyl)methyl]propanamide GTPL620 AC1NSKHB CHEMBL86828 (S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-cyclohexylmethyl)-propionamide PD 165929 BDBM50071754 Xenopus NMB D03TEJ PD-165929 [ Show all ]
Inchi Key	RVCSRPVACXMJEL-BHVANESWSA-N
Inchi ID	InChI=1S/C37H47N5O2/c1-25(2)28-15-13-16-29(26(3)4)33(28)41-35(44)42-36(5,22-27-23-39-31-17-8-7-14-30(27)31)34(43)40-24-37(19-10-6-11-20-37)32-18-9-12-21-38-32/h7-9,12-18,21,23,25-26,39H,6,10-11,19-20,22,24H2,1-5H3,(H,40,43)(H2,41,42,44)/t36-/m0/s1
PubChem CID	5311352
ChEMBL	CHEMBL86828
IUPHAR	N/A
BindingDB	50071754
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
305921	Bombesin receptor subtype-3	P32247	BRS3	Homo sapiens (Human)	399
305922	Gastrin-releasing peptide receptor	P21729	Grpr	Mus musculus (Mouse)	384
305924	Gastrin-releasing peptide receptor	P30550	GRPR	Homo sapiens (Human)	384
305923	Neuromedin-B receptor	P28336	NMBR	Homo sapiens (Human)	390
305925	Neuromedin-B receptor	P24053	Nmbr	Rattus norvegicus (Rat)	390

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