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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	US8685958, 8
Molecular formula	C25H26N4O4
IUPAC name	[3-[4-(6-oxa-2-azaspiro[3.4]octan-2-ylmethyl)phenoxy]azetidin-1-yl]-(5-phenyl-1,3,4-oxadiazol-2-yl)methanone
Molecular weight	446.507
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.4
Synonyms	BDBM119758 POWPLCVUTNYQQH-UHFFFAOYSA-N (3-(4-(6-oxa-2-azaspiro[3.4]octan-2-ylmethyl)phenoxy)azetidin-1-yl)(5-phenyl-1,3,4-oxadiazol-2-yl)methanone SCHEMBL14636952 CHEMBL3670640 US8685958, 7 [ Show all ]
Inchi Key	POWPLCVUTNYQQH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4O4/c30-24(23-27-26-22(33-23)19-4-2-1-3-5-19)29-13-21(14-29)32-20-8-6-18(7-9-20)12-28-15-25(16-28)10-11-31-17-25/h1-9,21H,10-17H2
PubChem CID	71226400
ChEMBL	CHEMBL3670640
IUPHAR	N/A
BindingDB	119758
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
265138	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
529126	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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