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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MRE-269
Molecular formula	C25H29N3O3
IUPAC name	2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]acetic acid
Molecular weight	419.525
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.5
Synonyms	2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid BCP16833 MolPort-009-019-324 Y0263 144382-EP2289518A1 ACT 333679 CHEMBL239226 MRE269 {4-[(5,6-Diphenyl-2-pyrazinyl)(isopropyl)amino]butoxy}acetic acid 2-[4-[[5,6-di(phenyl)pyrazin-2-yl]-propan-2-ylamino]butoxy]acetic acid ACT333679 GTPL5852 SCHEMBL676234 (4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid 475085-57-5 BRD-K57391913-001-01-4 MRE 269 Z-3153 144382-EP2292231A1 ACT-333679 CS-6104 OJQMKCBWYCWFPU-UHFFFAOYSA-N {4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}acetic acid 2-{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}acetic acid AKOS027307832 HY-79593 UNII-E9PC7N0DID (4-((5,6-Diphenylpyrazinyl)(1-methylethyl)amino)butoxy)-acetic acid CHEBI:90848 ZINC1553986 2-[4-[Isopropyl(5,6-diphenylpyrazine-2-yl)amino]butoxy]acetic acid ACT-333679;MRE269;MRE 269;ACT333679;ACT 333679 E9PC7N0DID SB19699 [ Show all ]
Inchi Key	OJQMKCBWYCWFPU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29N3O3/c1-19(2)28(15-9-10-16-31-18-23(29)30)22-17-26-24(20-11-5-3-6-12-20)25(27-22)21-13-7-4-8-14-21/h3-8,11-14,17,19H,9-10,15-16,18H2,1-2H3,(H,29,30)
PubChem CID	9931891
ChEMBL	N/A
IUPHAR	5852
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554480	Prostacyclin receptor	P43253	Ptgir	Rattus norvegicus (Rat)	416
554482	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
554479	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
554481	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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