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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Leu-Pro-Leu-Arg-Phe-NH2
Molecular formula	C32H53N9O5
IUPAC name	(2S)-1-[(2S)-2-amino-4-methylpentanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Molecular weight	643.834
Hydrogen bond acceptor	7
Hydrogen bond donor	7
XlogP	-0.5
Synonyms	DTXSID40551309 88280-21-1 Leu-Pro-Leu-Arg-Phe-amide CHEMBL2181305 L-Leucyl-L-prolyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-phenylalaninamide AKOS030610442 Leu-Pro-Leu-Arg-Phe-NH(2) CTK3B4743 L-Phenylalaninamide, L-leucyl-L-prolyl-L-leucyl-L-arginyl- [ Show all ]
Inchi Key	NIIZKQVUHKYFML-LROMGURASA-N
Inchi ID	InChI=1S/C32H53N9O5/c1-19(2)16-22(33)31(46)41-15-9-13-26(41)30(45)40-25(17-20(3)4)29(44)38-23(12-8-14-37-32(35)36)28(43)39-24(27(34)42)18-21-10-6-5-7-11-21/h5-7,10-11,19-20,22-26H,8-9,12-18,33H2,1-4H3,(H2,34,42)(H,38,44)(H,39,43)(H,40,45)(H4,35,36,37)/t22-,23-,24-,25-,26-/m0/s1
PubChem CID	13858264
ChEMBL	CHEMBL2181305
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
224063	Neuropeptide FF receptor 2	Q9EQD2	Npffr2	Rattus norvegicus (Rat)	417

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