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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL289740
Molecular formula	C17H28ClN3O3
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-hydroxybutan-2-yloxy)benzamide
Molecular weight	357.879
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.8
Synonyms	4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-[(2-hydroxy)but-3-yl]oxybenzamide threo-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide NDZDJUSQBJHCBF-UHFFFAOYSA-N 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide SCHEMBL9777109 BDBM50023802 erythro-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide [ Show all ]
Inchi Key	NDZDJUSQBJHCBF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H28ClN3O3/c1-5-21(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)24-12(4)11(3)22/h9-12,22H,5-8,19H2,1-4H3,(H,20,23)
PubChem CID	14116911
ChEMBL	CHEMBL289740
IUPHAR	N/A
BindingDB	50023802
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
220993	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
220994	D(2) dopamine receptor	Q9GJU1	DRD2	Canis lupus familiaris (Dog)	443

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