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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	PCO371
Molecular formula	C29H32F3N5O6S
IUPAC name	1-[3,5-dimethyl-4-[2-[[4-oxo-2-[4-(trifluoromethoxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-5,5-dimethylimidazolidine-2,4-dione
Molecular weight	635.659
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	3.7
Synonyms	SB19668 HY-100856 UNII-TE53TU0WSQ PCO-371 CHEMBL3976807 SCHEMBL17104864 1613373-33-3 J3.591.565F US9428505, Compound 7 BDBM64562 CS-0020524 TE53TU0WSQ 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- PC-0371 [ Show all ]
Inchi Key	LDZJFVOUPUFOHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H32F3N5O6S/c1-17-15-20(37-26(40)34-24(38)27(37,3)4)16-18(2)22(17)9-14-44(41,42)36-12-10-28(11-13-36)25(39)33-23(35-28)19-5-7-21(8-6-19)43-29(30,31)32/h5-8,15-16H,9-14H2,1-4H3,(H,33,35,39)(H,34,38,40)
PubChem CID	76283707
ChEMBL	CHEMBL3976807
IUPHAR	N/A
BindingDB	64562
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
534729	Parathyroid hormone/parathyroid hormone-related peptide receptor	P25961	Pth1r	Rattus norvegicus (Rat)	591

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