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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL475331
Molecular formula	C13H17N5
IUPAC name	2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Molecular weight	243.314
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.6
Synonyms	AKOS021819621 ZINC13234187 SCHEMBL11741104 BDBM50397290 2-(4-methylpiperazin-1-yl)quinazolin-4-amine MCULE-4822258576 AC1LQLRG VUF-10147 2-(4-methylpiperazino)-4-quinazolinamine MolPort-002-626-913 [ Show all ]
Inchi Key	KJVGBWURWKYDCH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H17N5/c1-17-6-8-18(9-7-17)13-15-11-5-3-2-4-10(11)12(14)16-13/h2-5H,6-9H2,1H3,(H2,14,15,16)
PubChem CID	1403136
ChEMBL	CHEMBL475331
IUPHAR	N/A
BindingDB	50397290
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
170849	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
170847	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
170843	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
170846	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
170845	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
170851	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
170842	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
170850	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
170848	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
170844	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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