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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3703204
Molecular formula	C25H30F4N2O3
IUPAC name	4-(2-ethylbutyl)-N-[3-[3-fluoro-5-(trifluoromethyl)phenoxy]phenyl]-4-hydroxypiperidine-1-carboxamide
Molecular weight	482.52
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.1
Synonyms	BDBM149713 US8975409, Comparative compound A
Inchi Key	JYUZIAXLZMPCJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30F4N2O3/c1-3-17(4-2)16-24(33)8-10-31(11-9-24)23(32)30-20-6-5-7-21(15-20)34-22-13-18(25(27,28)29)12-19(26)14-22/h5-7,12-15,17,33H,3-4,8-11,16H2,1-2H3,(H,30,32)
PubChem CID	91826297
ChEMBL	CHEMBL3703204
IUPHAR	N/A
BindingDB	149713
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
163381	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
460680	Sphingosine 1-phosphate receptor 2	P47752	S1pr2	Rattus norvegicus (Rat)	352

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