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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL196581
Molecular formula	C24H27F3N4O3
IUPAC name	N-[2-[3-(dimethylamino)propylamino]-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
Molecular weight	476.5
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.3
Synonyms	N-[2-(3-Dimethylamino-propylamino)-4-methyl-quinolin-6-yl]-2-(4-trifluoromethoxy-phenoxy)-acetamide SCHEMBL5910660 BDBM50172427
Inchi Key	IRTFNVYFUVVXDO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27F3N4O3/c1-16-13-22(28-11-4-12-31(2)3)30-21-10-5-17(14-20(16)21)29-23(32)15-33-18-6-8-19(9-7-18)34-24(25,26)27/h5-10,13-14H,4,11-12,15H2,1-3H3,(H,28,30)(H,29,32)
PubChem CID	11583744
ChEMBL	CHEMBL196581
IUPHAR	N/A
BindingDB	50172427
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
140342	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
140343	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
140341	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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