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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL268583
Molecular formula	C165H226N36O55
IUPAC name	(4S)-4-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-1,4-dioxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Molecular weight	3593.82
Hydrogen bond acceptor	60
Hydrogen bond donor	52
XlogP	-15.9
Synonyms	N/A
Inchi Key	IQCZSETUDYFDLT-HMJXBRMFSA-N
Inchi ID	InChI=1S/C165H226N36O55/c1-82(2)60-108(146(236)190-116(68-93-75-172-100-33-19-18-32-98(93)100)154(244)181-107(52-56-130(217)218)145(235)200-135(84(5)6)164(254)195-115(64-89-30-16-11-17-31-89)152(242)193-119(72-132(221)222)156(246)191-117(70-126(170)210)159(249)201-136(86(8)206)165(255)256)183-143(233)105(50-54-128(213)214)179-142(232)104(49-53-127(211)212)175-137(227)85(7)174-139(229)101(34-20-23-57-166)176-140(230)102(35-21-24-58-167)178-160(250)122(77-202)198-157(247)120(73-133(223)224)192-147(237)109(61-83(3)4)184-149(239)113(66-91-39-45-96(208)46-40-91)188-163(253)125(80-205)199-158(248)121(74-134(225)226)194-151(241)114(67-92-41-47-97(209)48-42-92)189-161(251)123(78-203)196-141(231)103(36-22-25-59-168)177-148(238)112(65-90-37-43-95(207)44-38-90)186-150(240)110(62-87-26-12-9-13-27-87)187-162(252)124(79-204)197-153(243)111(63-88-28-14-10-15-29-88)185-144(234)106(51-55-129(215)216)180-155(245)118(71-131(219)220)182-138(228)99(169)69-94-76-171-81-173-94/h9-19,26-33,37-48,75-76,81-86,99,101-125,135-136,172,202-209H,20-25,34-36,49-74,77-80,166-169H2,1-8H3,(H2,170,210)(H,171,173)(H,174,229)(H,175,227)(H,176,230)(H,177,238)(H,178,250)(H,179,232)(H,180,245)(H,181,244)(H,182,228)(H,183,233)(H,184,239)(H,185,234)(H,186,240)(H,187,252)(H,188,253)(H,189,251)(H,190,236)(H,191,246)(H,192,237)(H,193,242)(H,194,241)(H,195,254)(H,196,231)(H,197,243)(H,198,247)(H,199,248)(H,200,235)(H,201,249)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H,223,224)(H,225,226)(H,255,256)/t85-,86+,99-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,135-,136-/m0/s1
PubChem CID	44279575
ChEMBL	CHEMBL268583
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
139156	Glucagon receptor	P30082	Gcgr	Rattus norvegicus (Rat)	485

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