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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1279273
Molecular formula	C18H21N7O3
IUPAC name	3-[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrazol-4-yl]-1-[(1,5-dimethylpyrazol-3-yl)methyl]imidazolidine-2,4-dione
Molecular weight	383.412
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	0.3
Synonyms	BDBM211280 IGGVWAFAOKGAEF-UHFFFAOYSA-N 1-((1,5-dimethyl-1H-pyrazol-3-yl)methyl)-3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)imidazolidine-2,4-dione 1-((1,5-dimethyl-1H-pyrazol-3-yl) methyl)-3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl) imidazolidine-2,4-dione CHEMBL3895754 1-((1,5-dimethyl-1H-pyrazol-3-yl)methyl)-3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl) imidazolidine-2,4-dione US9247759, 10-28 [ Show all ]
Inchi Key	IGGVWAFAOKGAEF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H21N7O3/c1-11-5-14(20-22(11)4)7-23-10-17(26)25(18(23)27)15-6-19-24(8-15)9-16-12(2)21-28-13(16)3/h5-6,8H,7,9-10H2,1-4H3
PubChem CID	57944916
ChEMBL	CHEMBL3895754
IUPHAR	N/A
BindingDB	211280
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
520261	Taste receptor type 2 member 8	Q9NYW2	TAS2R8	Homo sapiens (Human)	309

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