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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Onapristone
Molecular formula	C29H39NO3
IUPAC name	(8S,11R,13R,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(3-hydroxypropyl)-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Molecular weight	449.635
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.2
Synonyms	11beta-(p-(Dimethylamino)phenyl)-17alpha-hydroxy-17-(3-hydroxypropyl)-13alpha-estra-4,9-dien-3-one CCRIS 6530 Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-, (11-beta,13-alpha,17-alpha)- K740 Onapristonum [Latin] ZK-299 AC1NSKQR D07MON Estra-4,9-dien-3-one,11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(3-hydroxypropyl)-, (11b,13a,17a)- Onapristona [Spanish] Xe 299 ZK98299 (8S,11R,13R,14S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-17-(3-hydroxypropyl)-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one C-22471 DB12637 HY-106389 Onapristone [INN] ZK 98.299 127138-89-0 CHEMBL1908373 Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-, (11beta,13alpha,17alpha)- LS-64722 SCHEMBL8740 ZK-98299 AKOS025311420 D09571 GTPL2882 ZINC3831947 11 beta-(4-dimethylaminophenyl)-17 alpha-hydroxy-17 beta-(3-hydroxypropyl)-13 alpha-methyl-4,9-gonadien-3-one C29H39NO3 DTXSID90242210 IVV-1001 Onapristonum ZK 98299 96346-61-1 CS-0025702 Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-,(11-beta,13-alpha,17-alpha)- Onapristona UNII-H6H7G23O3N ZK299 (8S,11R,13R,14S,17S)-11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-13-methyl-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one BDBM50366558 H6H7G23O3N Onapristone (INN) ZK 299 [ Show all ]
Inchi Key	IEXUMDBQLIVNHZ-YOUGDJEHSA-N
Inchi ID	InChI=1S/C29H39NO3/c1-28-18-25(19-5-8-21(9-6-19)30(2)3)27-23-12-10-22(32)17-20(23)7-11-24(27)26(28)13-15-29(28,33)14-4-16-31/h5-6,8-9,17,24-26,31,33H,4,7,10-16,18H2,1-3H3/t24-,25+,26-,28+,29+/m0/s1
PubChem CID	5311505
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB12637
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
549552	Adhesion G-protein coupled receptor D1	Q6QNK2	ADGRD1	Homo sapiens (Human)	874

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