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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198689
Molecular formula	C29H28Cl2N4O2
IUPAC name	N-[[4-(3-cyanophenyl)phenyl]methyl]-N-[2-(3,5-dichloroanilino)-2-oxoethyl]-3-pyrrolidin-1-ylpropanamide
Molecular weight	535.469
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50174825 N-(3''-cyano-biphenyl-4-ylmethyl)-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-3-pyrrolidin-1-yl-propionamide
Inchi Key	HKUXJPOEEIRZOB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H28Cl2N4O2/c30-25-15-26(31)17-27(16-25)33-28(36)20-35(29(37)10-13-34-11-1-2-12-34)19-21-6-8-23(9-7-21)24-5-3-4-22(14-24)18-32/h3-9,14-17H,1-2,10-13,19-20H2,(H,33,36)
PubChem CID	23573799
ChEMBL	CHEMBL198689
IUPHAR	N/A
BindingDB	50174825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
117536	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
117535	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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