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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3935030
Molecular formula	C25H35FN6O3
IUPAC name	2-[4-(2-fluoro-4-methoxyphenoxy)piperidin-1-yl]-N,N-dimethyl-3-(propan-2-ylamino)-7,8-dihydro-5H-pyrido[3,4-b]pyrazine-6-carboxamide
Molecular weight	486.592
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BDBM190935 HARGAPZWEJDNCT-UHFFFAOYSA-N SCHEMBL16818383 2-(4-(2-fluoro-4-methoxyphenoxy)piperidin-1-yl)-3-(isopropylamino)-N,N-dimethyl-7,8-dihydropyrido[3,4-b]pyrazine-6(5H)-carboxamide US9181249, 46
Inchi Key	HARGAPZWEJDNCT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H35FN6O3/c1-16(2)27-23-24(29-20-10-13-32(15-21(20)28-23)25(33)30(3)4)31-11-8-17(9-12-31)35-22-7-6-18(34-5)14-19(22)26/h6-7,14,16-17H,8-13,15H2,1-5H3,(H,27,28)
PubChem CID	118159393
ChEMBL	CHEMBL3935030
IUPHAR	N/A
BindingDB	190935
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517892	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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