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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1915865
Molecular formula	C29H29ClN2O5
IUPAC name	1-[4-chloro-3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]cyclopropane-1-carboxylic acid
Molecular weight	521.01
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50357620 SCHEMBL730925
Inchi Key	GUWAOSSGBYSTNR-NRFANRHFSA-N
Inchi ID	InChI=1S/C29H29ClN2O5/c1-17-12-20(36-16-21-15-32(3)24-6-4-5-7-25(24)37-21)13-18(2)26(17)27(33)31-23-14-19(8-9-22(23)30)29(10-11-29)28(34)35/h4-9,12-14,21H,10-11,15-16H2,1-3H3,(H,31,33)(H,34,35)/t21-/m0/s1
PubChem CID	57394587
ChEMBL	CHEMBL1915865
IUPHAR	N/A
BindingDB	50357620
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106001	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
106000	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
106002	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359

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