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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL217575
Molecular formula	C24H24F3N3O
IUPAC name	(E)-N-[4-(dimethylamino)-2-propylquinolin-6-yl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	427.471
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50193611 SCHEMBL6203989 (E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide SCHEMBL6203995
Inchi Key	GNDQGVNJNAVFDD-MDWZMJQESA-N
Inchi ID	InChI=1S/C24H24F3N3O/c1-4-5-18-15-22(30(2)3)20-14-19(11-12-21(20)28-18)29-23(31)13-8-16-6-9-17(10-7-16)24(25,26)27/h6-15H,4-5H2,1-3H3,(H,29,31)/b13-8+
PubChem CID	44417992
ChEMBL	CHEMBL217575
IUPHAR	N/A
BindingDB	50193611
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100469	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
100470	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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