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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL27155
Molecular formula	C17H20N4O3
IUPAC name	8-(4-hydroxyphenyl)-1,3-dipropyl-7H-purine-2,6-dione
Molecular weight	328.372
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.0
Synonyms	PDSP2_001118 BDBM82010 1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine NPC-205 94781-76-7 SCHEMBL1948455 8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione PDSP1_001134 BDBM50227340 [ Show all ]
Inchi Key	GLDYYZLOHBXJBU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20N4O3/c1-3-9-20-15-13(16(23)21(10-4-2)17(20)24)18-14(19-15)11-5-7-12(22)8-6-11/h5-8,22H,3-4,9-10H2,1-2H3,(H,18,19)
PubChem CID	135433923
ChEMBL	CHEMBL27155
IUPHAR	N/A
BindingDB	82010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
560395	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
560397	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
560394	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
560396	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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