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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3931736
Molecular formula	C22H25F4N5O2
IUPAC name	1-[2-(2,2-difluoroethylamino)-3-[4-(2,4-difluorophenoxy)piperidin-1-yl]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
Molecular weight	467.469
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	3.2
Synonyms	US9181249, 91 BDBM190978 GKYXBAFONJCMAT-UHFFFAOYSA-N 1-(2-((2,2-difluoroethyl)amino)-3-(4-(2,4-difluorophenoxy)piperidin-1-yl)-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl)ethanone SCHEMBL16818384
Inchi Key	GKYXBAFONJCMAT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25F4N5O2/c1-13(32)31-9-6-17-18(12-31)29-22(21(28-17)27-11-20(25)26)30-7-4-15(5-8-30)33-19-3-2-14(23)10-16(19)24/h2-3,10,15,20H,4-9,11-12H2,1H3,(H,27,28)
PubChem CID	118159394
ChEMBL	CHEMBL3931736
IUPHAR	N/A
BindingDB	190978
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517842	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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