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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377321
Molecular formula	C28H27F2N3O
IUPAC name	4-[4-(3-cyanophenyl)phenyl]-N-(3,4-difluorophenyl)-4-piperidin-4-ylbutanamide
Molecular weight	459.541
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.0
Synonyms	BDBM50186811 4a-(3''-cyano-biphenyl-4-yl)-N-(3,4-difluoro-phenyl)-4-piperidin-4-yl-butyramide
Inchi Key	GIUBHWVMASIGPO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H27F2N3O/c29-26-10-8-24(17-27(26)30)33-28(34)11-9-25(22-12-14-32-15-13-22)21-6-4-20(5-7-21)23-3-1-2-19(16-23)18-31/h1-8,10,16-17,22,25,32H,9,11-15H2,(H,33,34)
PubChem CID	44412852
ChEMBL	CHEMBL377321
IUPHAR	N/A
BindingDB	50186811
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
97561	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
97562	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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