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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL379489
Molecular formula	C33H34ClF3N4O
IUPAC name	N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[[4-[4-(3-cyanophenyl)phenyl]-1-cyclopentylpiperidin-4-yl]-methylamino]acetamide
Molecular weight	595.107
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	7.2
Synonyms	BDBM50186788
Inchi Key	GEIBEOSSYAMBAM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H34ClF3N4O/c1-40(22-31(42)39-27-13-14-30(34)29(20-27)33(35,36)37)32(15-17-41(18-16-32)28-7-2-3-8-28)26-11-9-24(10-12-26)25-6-4-5-23(19-25)21-38/h4-6,9-14,19-20,28H,2-3,7-8,15-18,22H2,1H3,(H,39,42)
PubChem CID	10312244
ChEMBL	CHEMBL379489
IUPHAR	N/A
BindingDB	50186788
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
94364	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
94363	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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