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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3940900
Molecular formula	C23H27F4N5O3
IUPAC name	1-[2-(2,2-difluoroethylamino)-3-[4-(2,4-difluorophenoxy)piperidin-1-yl]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]-2-methoxyethanone
Molecular weight	497.495
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BDBM190938 GDLRFXBQKYAJKF-UHFFFAOYSA-N 1-(2-((2,2-difluoroethyl)amino)-3-(4-(2,4-difluorophenoxy)piperidin-1-yl)-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl)-2-methoxyethanone SCHEMBL16818400 US9181249, 50
Inchi Key	GDLRFXBQKYAJKF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27F4N5O3/c1-34-13-21(33)32-9-6-17-18(12-32)30-23(22(29-17)28-11-20(26)27)31-7-4-15(5-8-31)35-19-3-2-14(24)10-16(19)25/h2-3,10,15,20H,4-9,11-13H2,1H3,(H,28,29)
PubChem CID	118159408
ChEMBL	CHEMBL3940900
IUPHAR	N/A
BindingDB	190938
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517815	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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