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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425979
Molecular formula	C26H28F3N3O
IUPAC name	(E)-N-[4-(diethylamino)-2-propylquinolin-6-yl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	455.525
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.4
Synonyms	BDBM50193642 (E)-N-(4-(diethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Inchi Key	FYXAYDYUZPOYEP-XNTDXEJSSA-N
Inchi ID	InChI=1S/C26H28F3N3O/c1-4-7-20-17-24(32(5-2)6-3)22-16-21(13-14-23(22)30-20)31-25(33)15-10-18-8-11-19(12-9-18)26(27,28)29/h8-17H,4-7H2,1-3H3,(H,31,33)/b15-10+
PubChem CID	44417996
ChEMBL	CHEMBL425979
IUPHAR	N/A
BindingDB	50193642
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
90634	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
90635	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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