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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3973483
Molecular formula	C23H29F2N5O2
IUPAC name	1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-(propan-2-ylamino)-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
Molecular weight	445.515
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.2
Synonyms	1-(2-(4-(2,4-difluorophenoxy)piperidin-1-yl)-3-(isopropylamino)-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl)ethanone US9181249, 141 BDBM190936 FSUXDPIOBQLEKO-UHFFFAOYSA-N 1-(2-(4-(2,4-difluorophenoxyl)piperidin-1-yl)-3-(isopropylamino)-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl)ethanone US9181249, 47 SCHEMBL16818199 [ Show all ]
Inchi Key	FSUXDPIOBQLEKO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29F2N5O2/c1-14(2)26-22-23(28-19-8-11-30(15(3)31)13-20(19)27-22)29-9-6-17(7-10-29)32-21-5-4-16(24)12-18(21)25/h4-5,12,14,17H,6-11,13H2,1-3H3,(H,26,27)
PubChem CID	91810771
ChEMBL	CHEMBL3973483
IUPHAR	N/A
BindingDB	190936
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517766	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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