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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL166875
Molecular formula	C28H30BrN5O6S
IUPAC name	N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-methylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
Molecular weight	644.541
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50107565 N-[2-Methyl-5-(2-methoxyphenoxy)-6-[2-(5-bromo-2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-4-(tert-butyl)benzenesulfonamide N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yl]-4-tert-butyl-benzenesulfonamide
Inchi Key	FPWSONXCLFDXOT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H30BrN5O6S/c1-18-32-25(34-41(35,36)21-12-10-19(11-13-21)28(2,3)4)24(40-23-9-7-6-8-22(23)37-5)26(33-18)38-14-15-39-27-30-16-20(29)17-31-27/h6-13,16-17H,14-15H2,1-5H3,(H,32,33,34)
PubChem CID	44380954
ChEMBL	CHEMBL166875
IUPHAR	N/A
BindingDB	50107565
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84434	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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