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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL439358
Molecular formula	C23H22F3N3O
IUPAC name	(E)-N-(4-amino-2-tert-butylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	413.444
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.4
Synonyms	SCHEMBL6204354 BDBM50193637 SCHEMBL6204350 (E)-N-(4-amino-2-tert-butylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Inchi Key	FOZHABDRGZDSMZ-IZZDOVSWSA-N
Inchi ID	InChI=1S/C23H22F3N3O/c1-22(2,3)20-13-18(27)17-12-16(9-10-19(17)29-20)28-21(30)11-6-14-4-7-15(8-5-14)23(24,25)26/h4-13H,1-3H3,(H2,27,29)(H,28,30)/b11-6+
PubChem CID	16049789
ChEMBL	CHEMBL439358
IUPHAR	N/A
BindingDB	50193637
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83775	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
83774	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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