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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CP-154526
Molecular formula	C23H32N4
IUPAC name	N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
Molecular weight	364.537
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	6.2
Synonyms	AKOS032946677 CHEMBL9946 FHQYJZCJRZHINA-UHFFFAOYSA-N N-butyl-N-ethyl-7-mesityl-2,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine BDBM50369802 LS-139512 PDSP2_001283 AB07693 CHEMBL475903 CP154526 N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine ZINC1539133 BCP26372 CP 154,526 GTPL3495 NCGC00378725-02 157286-86-7 butyl-(2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo(2,3-d)pyrimidin-4-yl)ethylamine CP-154526-1 N-BUTYL-N-ETHYL-2,5-DIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE SCHEMBL5707848 AC1NSJWW D02IOC N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[3,2-e]pyrimidin-4-amine BDBM50058163 CP-154,526 KB-76171 PDSP1_001299 Butyl-ethyl-[2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amine CP154,526 N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo(2,3-d)pyrimidin-4-amine UNII-9A549FB00R 9A549FB00R [ Show all ]
Inchi Key	FHQYJZCJRZHINA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3
PubChem CID	5311055
ChEMBL	CHEMBL9946
IUPHAR	3495
BindingDB	50058163, 50369802
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78595	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
78596	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
78597	Corticotropin-releasing factor receptor 2	P47866	Crhr2	Rattus norvegicus (Rat)	411

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