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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ALX-5407
Molecular formula	C24H24FNO3
IUPAC name	2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid
Molecular weight	393.458
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	(R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)propyl)(methyl)amino)acetic acid ALX 5407 D05WWJ ZINC3996003 2-[[3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid BDBM50149871 NCGC00025278-01 571147-18-7 SR-01000597496-1 (R)-NFPS GTPL4618 {[(R)-3-(Biphenyl-4-yloxy)-3-(4-fluoro-phenyl)-propyl]-methyl-amino}-acetic acid 2-{[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl](methyl)amino}acetic acid BRD-K53979406-003-01-0 SCHEMBL1052569 (r)-(n-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl])sarcosine AC1O7H1E CHEMBL180966 Tocris-1757 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid ALX5407 KB-74627 CHEBI:92943 SR-01000597496 [ Show all ]
Inchi Key	FDORQEIHOKEJNX-HSZRJFAPSA-N
Inchi ID	InChI=1S/C24H24FNO3/c1-26(17-24(27)28)16-15-23(20-7-11-21(25)12-8-20)29-22-13-9-19(10-14-22)18-5-3-2-4-6-18/h2-14,23H,15-17H2,1H3,(H,27,28)/t23-/m1/s1
PubChem CID	6604909
ChEMBL	CHEMBL180966
IUPHAR	N/A
BindingDB	50149871
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
75759	Galanin receptor type 1	Q62805	Galr1	Rattus norvegicus (Rat)	346

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