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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL212256
Molecular formula	C28H22F4N4
IUPAC name	3-[4-[2-[5-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]-6-azaspiro[2.5]octan-2-yl]phenyl]benzonitrile
Molecular weight	490.506
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.9
Synonyms	BDBM50186824 SCHEMBL14532585 4''-[1-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-6-aza-spiro[2.5]oct-1-yl]-biphenyl-3-carbonitrile SCHEMBL5383958
Inchi Key	FDLKOSUENWKSCR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H22F4N4/c29-22-14-24-23(13-21(22)28(30,31)32)35-25(36-24)27(16-26(27)8-10-34-11-9-26)20-6-4-18(5-7-20)19-3-1-2-17(12-19)15-33/h1-7,12-14,34H,8-11,16H2,(H,35,36)
PubChem CID	11191034
ChEMBL	CHEMBL212256
IUPHAR	N/A
BindingDB	50186824
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
75680	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
75681	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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