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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL424721
Molecular formula	C22H22F3N3O
IUPAC name	N-(4-amino-2-propylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]propanamide
Molecular weight	401.433
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50193624 FCCWHXNZERKPRB-UHFFFAOYSA-N SCHEMBL6202397 N-(4-amino-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide N-(4-amino-2-propylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]propanamide
Inchi Key	FCCWHXNZERKPRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22F3N3O/c1-2-3-16-13-19(26)18-12-17(9-10-20(18)27-16)28-21(29)11-6-14-4-7-15(8-5-14)22(23,24)25/h4-5,7-10,12-13H,2-3,6,11H2,1H3,(H2,26,27)(H,28,29)
PubChem CID	44417823
ChEMBL	CHEMBL424721
IUPHAR	N/A
BindingDB	50193624
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
74796	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
74795	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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