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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL146557
Molecular formula	C23H24N4O
IUPAC name	3-[1-[(1-phenylpyrrol-3-yl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular weight	372.472
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50048236 1-[1-(1-Phenyl-1H-pyrrol-3-ylmethyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one
Inchi Key	DZKGMYCNIICGIS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24N4O/c28-23-24-21-8-4-5-9-22(21)27(23)20-11-13-25(14-12-20)16-18-10-15-26(17-18)19-6-2-1-3-7-19/h1-10,15,17,20H,11-14,16H2,(H,24,28)
PubChem CID	10761828
ChEMBL	CHEMBL146557
IUPHAR	N/A
BindingDB	50048236
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72747	D(2) dopamine receptor	P52702	DRD2	Chlorocebus aethiops (Green monkey)	443
72748	D(3) dopamine receptor	P52703	DRD3	Chlorocebus aethiops (Green monkey)	400
72749	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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