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Ligand

NameCHEMBL384547
Molecular formulaC23H20F3N3O
IUPAC name(E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight411.428
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP4.8
SynonymsSCHEMBL6204528
BDBM50193620
SCHEMBL6204521
(E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Inchi KeyDZBRSGDTRPYNOH-IZZDOVSWSA-N
Inchi IDInChI=1S/C23H20F3N3O/c24-23(25,26)16-7-4-14(5-8-16)6-11-22(30)28-17-9-10-20-18(12-17)19(27)13-21(29-20)15-2-1-3-15/h4-13,15H,1-3H2,(H2,27,29)(H,28,30)/b11-6+
PubChem CID44417947
ChEMBLCHEMBL384547
IUPHARN/A
BindingDB50193620
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
72488Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
72489Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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