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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1762268
Molecular formula	C18H28N4O3S
IUPAC name	1-[4-[[(1R,2R,4S)-2-bicyclo[2.2.1]heptanyl]amino]pyridin-3-yl]sulfonyl-3-tert-butyl-1-methylurea
Molecular weight	380.507
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.9
Synonyms	BDBM50340985 (+/-)-4-((exo)-bicyclo[2.2.1]heptan-2-ylamino)-N-(tert-butylcarbamoyl)-N-methylpyridine-3-sulfonamide
Inchi Key	DTNIFHDQESVTDC-GZBFAFLISA-N
Inchi ID	InChI=1S/C18H28N4O3S/c1-18(2,3)21-17(23)22(4)26(24,25)16-11-19-8-7-14(16)20-15-10-12-5-6-13(15)9-12/h7-8,11-13,15H,5-6,9-10H2,1-4H3,(H,19,20)(H,21,23)/t12-,13+,15+/m0/s1
PubChem CID	54583451
ChEMBL	CHEMBL1762268
IUPHAR	N/A
BindingDB	50340985
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68480	Bombesin receptor subtype-3	P32247	BRS3	Homo sapiens (Human)	399
68481	Bombesin receptor subtype-3	O54798	Brs3	Mus musculus (Mouse)	399

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