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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL208573
Molecular formula	C29H22F4N4O
IUPAC name	3-[4-[(1-acetylpiperidin-4-ylidene)-[5-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]phenyl]benzonitrile
Molecular weight	518.516
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.8
Synonyms	4''-[(1-acetyl-piperidin-4-ylidene)-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-methyl]-biphenyl-3-carbonitrile BDBM50186844
Inchi Key	DQRDAEGIDASIQJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H22F4N4O/c1-17(38)37-11-9-21(10-12-37)27(20-7-5-19(6-8-20)22-4-2-3-18(13-22)16-34)28-35-25-14-23(29(31,32)33)24(30)15-26(25)36-28/h2-8,13-15H,9-12H2,1H3,(H,35,36)
PubChem CID	44413299
ChEMBL	CHEMBL208573
IUPHAR	N/A
BindingDB	50186844
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66559	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353
66561	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
66560	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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