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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1222492
Molecular formula	C28H31BrN2O3S
IUPAC name	4-bromo-7-methoxy-1-(2-methoxyethyl)-5-[(2-methylsulfinylphenyl)methyl]-2-(4-propan-2-ylphenyl)benzimidazole
Molecular weight	555.531
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.7
Synonyms	SCHEMBL2503512 4-Bromo-2-(4-isopropyl-phenyl)-5-(2-methanesulfinyl-benzyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole BDBM50325519 DOCSKUXMRHPMRS-UHFFFAOYSA-N 4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-5-(2-(methylsulfinyl)benzyl)-1H-benzo[d]imidazole
Inchi Key	DOCSKUXMRHPMRS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31BrN2O3S/c1-18(2)19-10-12-20(13-11-19)28-30-26-25(29)22(16-21-8-6-7-9-24(21)35(5)32)17-23(34-4)27(26)31(28)14-15-33-3/h6-13,17-18H,14-16H2,1-5H3
PubChem CID	11398805
ChEMBL	CHEMBL1222492
IUPHAR	N/A
BindingDB	50325519
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64896	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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