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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL209059
Molecular formula	C30H29F2N3O3
IUPAC name	ethyl 4-[4-(3-cyanophenyl)phenyl]-4-[3-(3,4-difluoroanilino)-3-oxopropyl]piperidine-1-carboxylate
Molecular weight	517.577
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.4
Synonyms	BDBM50186774 4-(3''-cyano-biphenyl-4-yl)-4-[2-(3,4-difluoro-phenylcarbamoyl)-ethyl]-piperidine-1-carboxylic acid ethyl ester
Inchi Key	DKWJUJXHOLOFIS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H29F2N3O3/c1-2-38-29(37)35-16-14-30(15-17-35,13-12-28(36)34-25-10-11-26(31)27(32)19-25)24-8-6-22(7-9-24)23-5-3-4-21(18-23)20-33/h3-11,18-19H,2,12-17H2,1H3,(H,34,36)
PubChem CID	20608996
ChEMBL	CHEMBL209059
IUPHAR	N/A
BindingDB	50186774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62672	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
62673	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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