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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL144678
Molecular formula	C8H10FNO4
IUPAC name	(1S,2R,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	203.169
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.2
Synonyms	(1S,2R,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (1alpha,5alpha)-2-Amino-3alpha-fluorobicyclo[3.1.0]hexane-2beta,6alpha-dicarboxylic acid BDBM50094846
Inchi Key	DIWVNJFXRKZAGI-PQDNFBNRSA-N
Inchi ID	InChI=1S/C8H10FNO4/c9-3-1-2-4(6(11)12)5(2)8(3,10)7(13)14/h2-5H,1,10H2,(H,11,12)(H,13,14)/t2-,3+,4-,5-,8+/m0/s1
PubChem CID	10822010
ChEMBL	CHEMBL144678
IUPHAR	N/A
BindingDB	50094846
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61165	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559172	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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