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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3902181
Molecular formula	C23H32FN5O2
IUPAC name	2-[4-(2-fluoro-4-methoxyphenoxy)piperidin-1-yl]-6-methyl-N-propan-2-yl-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-3-amine
Molecular weight	429.54
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.6
Synonyms	2-(4-(2-fluoro-4-methoxyphenoxy)piperidin-1-yl)-N-isopropyl-6-methyl-5,6,7,8-tetrahydropyrido[3,4-b]pyrazin-3-amine US9181249, 74 BDBM190961 DFMRQAQETRMYOT-UHFFFAOYSA-N SCHEMBL16818131
Inchi Key	DFMRQAQETRMYOT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32FN5O2/c1-15(2)25-22-23(27-19-9-10-28(3)14-20(19)26-22)29-11-7-16(8-12-29)31-21-6-5-17(30-4)13-18(21)24/h5-6,13,15-16H,7-12,14H2,1-4H3,(H,25,26)
PubChem CID	118159150
ChEMBL	CHEMBL3902181
IUPHAR	N/A
BindingDB	190961
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517616	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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