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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ACIFRAN
Molecular formula	C12H10O4
IUPAC name	5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
Molecular weight	218.208
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.7
Synonyms	C-11906 DFDGRKNOFOJBAJ-UHFFFAOYSA-N HMS3268E04 SR-01000597500 (+)-acifran 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (-)- 5-methyl-4-oxo-5-phenyl-furan-2-carboxylic acid Acifranum [INN-Latin] DSSTox_RID_81057 NCGC00025283-01 Tox21_110958_1 (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarbonsaeure 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid 61IZ92GN57 Acifran (USAN/INN) AY 25712 D02753 FT-0641407 Reductol (TN) 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (+)- 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid 77103-92-5 Acifran, (-)- BDBM50208138 CAS-72420-38-3 DSSTox_CID_25685 LS-70167 SR-01000597500-1 (+-)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid 2-Furancarboxylic acid,4,5-dihydro-5-methyl-4-oxo-5-phenyl- 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid Acifran (+)-form [MI] AKOS022652744 CHEMBL278488 DTXSID9045685 NCGC00025283-02 UNII-61IZ92GN57 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYLFURAN-2-CARBOXYLIC ACID 72420-38-3 Acifran [USAN:INN] AY-25,712 BN0050 D0K1HO GTPL1595 SCHEMBL188221 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-, (+-)- 5-methyl-4-oxo-5-phenyl-4,5-dihydrofuran-2-carboxylic acid AC1L1BD7 Acifranum CC-23734 DSSTox_GSID_45685 MolPort-003-666-847 Tox21_110958 (-)-acifran 2-methyl-2-phenyl-3(2H)furanone-5-carboxylic acid Acifran (-)-form [MI] AN-8738 CTK8F7568 FP3LLW01BL Reductol UNII-FP3LLW01BL 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl- 5-methyl-4-oxo-5-phenyl-4,5-dihydro-2-furancarboxylic acid 77103-91-4 Acifran, (+)- AY-25712 [ Show all ]
Inchi Key	DFDGRKNOFOJBAJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
PubChem CID	51576
ChEMBL	CHEMBL278488
IUPHAR	1595
BindingDB	50208138
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58465	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
58466	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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