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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3647026
Molecular formula	C28H33ClN8O
IUPAC name	6-(4-chloro-5-cyclopropyl-2-methylpyrazol-3-yl)-2-(3,5-dimethyl-2H-indazol-4-yl)-4-[(2S,3R)-3-methoxy-2-methylazetidin-1-yl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine
Molecular weight	533.077
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.4
Synonyms	US8846656, 69-I BDBM134594 SCHEMBL15105085
Inchi Key	DESIJHPAUGYDSK-HRAATJIYSA-N
Inchi ID	InChI=1S/C28H33ClN8O/c1-14-6-9-20-23(15(2)32-33-20)22(14)26-30-19-10-11-36(28-24(29)25(17-7-8-17)34-35(28)4)12-18(19)27(31-26)37-13-21(38-5)16(37)3/h6,9,16-17,21H,7-8,10-13H2,1-5H3,(H,32,33)/t16-,21+/m0/s1
PubChem CID	89685923
ChEMBL	CHEMBL3647026
IUPHAR	N/A
BindingDB	134594
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
470098	C5a anaphylatoxin chemotactic receptor 1	P21730	C5AR1	Homo sapiens (Human)	350

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