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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL263649
Molecular formula	C21H18F3N5O
IUPAC name	7-(dimethylamino)-4-(3-imidazol-1-ylphenyl)-8-(trifluoromethyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	413.404
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.2
Synonyms	SCHEMBL6163709 7-Dimethylamino-4-(3-imidazol-1-yl-phenyl)-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one BDBM50376482 DDDRVKGHRFVCSK-UHFFFAOYSA-N
Inchi Key	DDDRVKGHRFVCSK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18F3N5O/c1-28(2)19-10-18-17(9-15(19)21(22,23)24)27-20(30)11-16(26-18)13-4-3-5-14(8-13)29-7-6-25-12-29/h3-10,12H,11H2,1-2H3,(H,27,30)
PubChem CID	10201802
ChEMBL	CHEMBL263649
IUPHAR	N/A
BindingDB	50376482
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57002	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559026	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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