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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1289679
Molecular formula	C24H26ClF3N4O
IUPAC name	(5S,7R)-N-(1-adamantyl)-5-(3-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
Molecular weight	478.944
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.9
Synonyms	N-(1-Adamantyl)-5-(3-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-3-carboxamide BDBM50331952
Inchi Key	CWFQEEBEAWPVIP-JFUWQCHASA-N
Inchi ID	InChI=1S/C24H26ClF3N4O/c25-17-3-1-2-16(7-17)19-8-20(24(26,27)28)32-21(30-19)18(12-29-32)22(33)31-23-9-13-4-14(10-23)6-15(5-13)11-23/h1-3,7,12-15,19-20,30H,4-6,8-11H2,(H,31,33)/t13?,14?,15?,19-,20+,23?/m0/s1
PubChem CID	136032598
ChEMBL	CHEMBL1289679
IUPHAR	N/A
BindingDB	50331952
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558881	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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